日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Complete structures of the YenTc holotoxin prepore and pore reveal the evolutionary basis for chitinase incorporation into ABC toxins

YenTc全毒素前孔和孔的完整结构揭示了几丁质酶整合到ABC毒素中的进化基础

Low, Yu Shang; Roche, Solace G; Aleksandrova, Nadezhda A; Foley, Gabriel; Low, Jason Kk; Box, Joseph K; Croll, Tristan I; Chassagnon, Irene R; Lott, J Shaun; Deplazes, Evelyne; Bodén, Mikael; Hurst, Mark Rh; Piper, Sarah J; Landsberg, Michael J

Structural basis of modified ligand selectivity from N-terminal PAC1R alternative splicing

PAC1R N端选择性剪接修饰配体选择性的结构基础

Lu, Jessica J; Deganutti, Giuseppe; Li, Miaomiao; Humphrys, Laura J; Li, Yandi; Nettleton, Theodore J; Venugopal, Hariprasad; Julita, Villy; Christopoulos, George; Reynolds, Christopher A; Sexton, Patrick M; Wootten, Denise; Zhao, Peishen; Piper, Sarah J

Impact of secretin receptor homo-dimerization on natural ligand binding

促胰液素受体同源二聚化对天然配体结合的影响

Harikumar, Kaleeckal G; Piper, Sarah J; Christopoulos, Arthur; Wootten, Denise; Sexton, Patrick M; Miller, Laurence J

New Insights into the Structure and Function of Class B1 GPCRs

B1类GPCR的结构和功能的新见解

Cary, Brian P; Zhang, Xin; Cao, Jianjun; Johnson, Rachel M; Piper, Sarah J; Gerrard, Elliot J; Wootten, Denise; Sexton, Patrick M

Membranes under the Magnetic Lens: A Dive into the Diverse World of Membrane Protein Structures Using Cryo-EM.

磁透镜下的膜:利用冷冻电镜探索膜蛋白结构的多元世界

Piper Sarah J, Johnson Rachel M, Wootten Denise, Sexton Patrick M

Targeting VIP and PACAP Receptor Signaling: New Insights into Designing Drugs for the PACAP Subfamily of Receptors

靶向VIP和PACAP受体信号通路:PACAP受体亚家族药物设计的新见解

Lu, Jessica; Piper, Sarah J; Zhao, Peishen; Miller, Laurence J; Wootten, Denise; Sexton, Patrick M

Secretin Amino-Terminal Structure-Activity Relationships and Complementary Mutagenesis at the Site of Docking to the Secretin Receptor

促胰液素氨基末端结构-活性关系及与促胰液素受体结合位点的互补突变

Milburn, Juliana E; Harikumar, Kaleeckal G; Piper, Sarah J; Raval, Sweta; Christopoulos, Arthur; Wootten, Denise; Sexton, Patrick M; Miller, Laurence J

Desacetyl-α-melanocyte stimulating hormone and α-melanocyte stimulating hormone are required to regulate energy balance

去乙酰化α-促黑素细胞激素和α-促黑素细胞激素是调节能量平衡所必需的。

Mountjoy, Kathleen G; Caron, Alexandre; Hubbard, Kristina; Shome, Avik; Grey, Angus C; Sun, Bo; Bould, Sarah; Middleditch, Martin; Pontré, Beau; McGregor, Ailsa; Harris, Paul W R; Kowalczyk, Renata; Brimble, Margaret A; Botha, Rikus; Tan, Karen M L; Piper, Sarah J; Buchanan, Christina; Lee, Syann; Coll, Anthony P; Elmquist, Joel K

A comparative study of the central effects of specific proopiomelancortin (POMC)-derived melanocortin peptides on food intake and body weight in pomc null mice

对特定促阿片黑素原 (POMC) 衍生的黑素皮质素肽对 pomc 基因敲除小鼠食物摄入量和体重的中枢效应进行比较研究

Tung, Y C Loraine; Piper, Sarah J; Yeung, Debra; O'Rahilly, Stephen; Coll, Anthony P