日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Immunogenicity risk assessment for tailored mitigation and monitoring of biotherapeutics during development: recommendations from the European Immunogenicity Platform

针对生物治疗药物研发过程中的免疫原性风险评估,制定个性化缓解措施并进行监测:欧洲免疫原性平台的建议

Grudzinska-Goebel, Joanna; Benstein, Karin; Bloem, Karien; Cowan, Kyra J; Gorovits, Boris; Jadhav, Maria; Janssen, Melody; Jawa, Vibha; Kiessling, Andrea; Kramer, Daniel; Kromminga, Arno; van der Linden, Marcel; Liu, Susana; Lotz, Gregor P; Luo, Linlin; Malisauskas, Mantas; Marban-Doran, Céline; Mytych, Daniel T; Oquendo Cifuentes, Elisa; Pippig, Susanne; Ribes, Sandra; Rouwette, Myrthe; Shao, Weiping; Tourdot, Sophie; Weldingh, Karin Nana; Snoeck, Veerle

Picomolar inhibition of SARS-CoV-2 variants of concern by an engineered ACE2-IgG4-Fc fusion protein

工程化的 ACE2-IgG4-Fc 融合蛋白对令人担忧的 SARS-CoV-2 变体具有皮摩尔级抑制作用

Hristo L Svilenov, Julia Sacherl, Alwin Reiter, Lisa S Wolff, Cho-Chin Cheng, Marcel Stern, Vincent Grass, Martin Feuerherd, Frank-Peter Wachs, Nicole Simonavicius, Susanne Pippig, Florian Wolschin, Oliver T Keppler, Johannes Buchner, Carsten Brockmeyer, Ulrike Protzer

Different Vinculin Binding Sites Use the Same Mechanism to Regulate Directional Force Transduction

不同的黏着斑蛋白结合位点利用相同的机制来调节定向力传递。

Kluger, Carleen; Braun, Lukas; Sedlak, Steffen M; Pippig, Diana A; Bauer, Magnus S; Miller, Ken; Milles, Lukas F; Gaub, Hermann E; Vogel, Viola

Direction Matters: Monovalent Streptavidin/Biotin Complex under Load

方向很重要:负载下的单价链霉亲和素/生物素复合物

Sedlak, Steffen M; Schendel, Leonard C; Melo, Marcelo C R; Pippig, Diana A; Luthey-Schulten, Zaida; Gaub, Hermann E; Bernardi, Rafael C

Structural and mechanistic insights into mechanoactivation of focal adhesion kinase

对黏着斑激酶机械激活的结构和机制的深入了解

Bauer, Magnus Sebastian; Baumann, Fabian; Daday, Csaba; Redondo, Pilar; Durner, Ellis; Jobst, Markus Andreas; Milles, Lukas Frederik; Mercadante, Davide; Pippig, Diana Angela; Gaub, Hermann Eduard; Gräter, Frauke; Lietha, Daniel

Functional Polymers and Polymeric Materials From Renewable Alpha-Unsaturated Gamma-Butyrolactones

由可再生α-不饱和γ-丁内酯制备的功能性聚合物和聚合物材料

Kollár, Jozef; Danko, Martin; Pippig, Falko; Mosnáček, Jaroslav

High-Temperature Wear Behaviour of Spark Plasma Sintered AlCoCrFeNiTi(0.5) High-Entropy Alloy

火花等离子烧结AlCoCrFeNiTi(0.5)高熵合金的高温磨损行为

Löbel, Martin; Lindner, Thomas; Pippig, Robert; Lampke, Thomas

Increasing evidence of mechanical force as a functional regulator in smooth muscle myosin light chain kinase

越来越多的证据表明机械力是平滑肌肌球蛋白轻链激酶的功能调节因子

Baumann, Fabian; Bauer, Magnus Sebastian; Rees, Martin; Alexandrovich, Alexander; Gautel, Mathias; Pippig, Diana Angela; Gaub, Hermann Eduard

Monodisperse measurement of the biotin-streptavidin interaction strength in a well-defined pulling geometry

在明确的拉伸几何结构中,对生物素-链霉亲和素相互作用强度进行单分散测量。

Sedlak, Steffen M; Bauer, Magnus S; Kluger, Carleen; Schendel, Leonard C; Milles, Lukas F; Pippig, Diana A; Gaub, Hermann E

Force sensing by the vascular protein von Willebrand factor is tuned by a strong intermonomer interaction

血管蛋白血管性血友病因子对力的感知是通过强烈的单体间相互作用来调节的。

Müller, Jochen P; Mielke, Salomé; Löf, Achim; Obser, Tobias; Beer, Christof; Bruetzel, Linda K; Pippig, Diana A; Vanderlinden, Willem; Lipfert, Jan; Schneppenheim, Reinhard; Benoit, Martin