日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Deciphering the Dialogue between Brain Tumors, Neurons, and Astrocytes

解读脑肿瘤、神经元和星形胶质细胞之间的对话

Westerlund, Leevi H; Bergström, Camilla K; Laakkonen, Pirjo M; Le Joncour, Vadim

Alpha-B-Crystallin overexpression is sufficient to promote tumorigenesis and metastasis in mice

Alpha-B-Crystallin 过表达足以促进小鼠的肿瘤发生和转移

Behnam Rashidieh, Amanda Louise Bain, Simon Manuel Tria, Sowmya Sharma, Cameron Allan Stewart, Jacinta Ley Simmons, Pirjo M Apaja, Pascal H G Duijf, John Finnie, Kum Kum Khanna

Ubr1-induced selective endophagy/autophagy protects against the endosomal and Ca2+-induced proteostasis disease stress

Ubr1 诱导的选择性内吞/自噬可抵御内体和 Ca2+ 诱导的蛋白质稳态疾病应激

Ben B Wang, Haijin Xu, Sandra Isenmann, Cheng Huang, Xabier Elorza-Vidal, Grigori Y Rychkov, Raúl Estévez, Ralf B Schittenhelm, Gergely L Lukacs, Pirjo M Apaja3

Reprogramming endo-lysosomal proteostasis disease stress by UBR1- and arginylation-driven endophagy and autophagy protein quality control

UBR1和精氨酸化驱动的内吞作用和自噬作用对内溶酶体蛋白稳态疾病应激的重编程蛋白质质量控制

Wang, Ben B; Apaja, Pirjo M

Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes

Endofin 是 HD-PTP 和 ESCRT-0 相互依赖的内体泛素化跨膜货物分选所必需的

Jalal M Kazan, Guillaume Desrochers, Claire E Martin, Hyeonju Jeong, Dmitri Kharitidi, Pirjo M Apaja, Ariel Roldan, Nicole St Denis, Anne-Claude Gingras, Gergely L Lukacs, Arnim Pause

Control of membrane protein homeostasis by a chaperone-like glial cell adhesion molecule at multiple subcellular locations

类似分子伴侣的神经胶质细胞粘附分子在多个亚细胞位置控制膜蛋白稳态

Haijin Xu, Sandra Isenmann, Tania López-Hernández, Raúl Estévez, Gergely L Lukacs, Pirjo M Apaja1

Chaperone-Independent Peripheral Quality Control of CFTR by RFFL E3 Ligase

RFFL E3 连接酶对 CFTR 进行不依赖伴侣的外周质量控制

Tsukasa Okiyoneda, Guido Veit, Ryohei Sakai, Misaki Aki, Takeshi Fujihara, Momoko Higashi, Seiko Susuki-Miyata, Masanori Miyata, Norihito Fukuda, Akihiko Yoshida, Haijin Xu, Pirjo M Apaja, Gergely L Lukacs

Chaperones rescue the energetic landscape of mutant CFTR at single molecule and in cell

分子伴侣在单分子和细胞中拯救突变 CFTR 的能量格局

Miklos Bagdany, Guido Veit, Ryosuke Fukuda, Radu G Avramescu, Tsukasa Okiyoneda, Imad Baaklini, Jay Singh, Guy Sovak, Haijin Xu, Pirjo M Apaja, Sara Sattin, Lenore K Beitel, Ariel Roldan, Giorgio Colombo, William Balch, Jason C Young, Gergely L Lukacs

Leukoencephalopathy-causing CLCN2 mutations are associated with impaired Cl- channel function and trafficking

导致白质脑病的 CLCN2 突变与 Cl- 通道功能和运输受损有关

Héctor Gaitán-Peñas, Pirjo M Apaja, Tanit Arnedo, Aida Castellanos, Xabier Elorza-Vidal, David Soto, Xavier Gasull, Gergely L Lukacs, Raúl Estévez

Ribosomal Stalk Protein Silencing Partially Corrects the ΔF508-CFTR Functional Expression Defect

核糖体柄蛋白沉默部分纠正了 ΔF508-CFTR 功能表达缺陷

Guido Veit, Kathryn Oliver, Pirjo M Apaja, Doranda Perdomo, Aurélien Bidaud-Meynard, Sheng-Ting Lin, Jingyu Guo, Mert Icyuz, Eric J Sorscher, John L Hartman IV, Gergely L Lukacs