From Serendipity to Rational Identification of the 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3- d]pyrimidin-4(3 H)-one Core as a New Chemotype of AKT1 Inhibitors for Acute Myeloid Leukemia
从偶然发现到合理鉴定 5,6,7,8-四氢苯并[4,5]噻吩并[2,3- d]嘧啶-4(3 H)-酮核心为治疗急性髓系白血病的 AKT1 抑制剂新化学型
期刊:Pharmaceutics
影响因子:4.9
doi:10.3390/pharmaceutics14112295
Andrea Astolfi, Francesca Milano, Deborah Palazzotti, Jose Brea, Maria Chiara Pismataro, Mariangela Morlando, Oriana Tabarrini, Maria Isabel Loza, Serena Massari, Maria Paola Martelli, Maria Letizia Barreca
