日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Epimaps of the SARS-CoV-2 Receptor-Binding Domain Mutational Landscape: Insights into Protein Stability, Epitope Prediction, and Antibody Binding

SARS-CoV-2受体结合域突变图谱:蛋白质稳定性、表位预测和抗体结合的见解

Pitsillou, Eleni; El-Osta, Assam; Hung, Andrew; Karagiannis, Tom C

Set7 Methyltransferase and Phenotypic Switch in Diabetic Glomerular Endothelial Cells.

Set7甲基转移酶与糖尿病肾小球内皮细胞的表型转换

Maxwell Scott, Okabe Jun, Kaipananickal Harikrishnan, Rodriguez Hanah, Khurana Ishant, Al-Hasani Keith, Chow Bryna S M, Pitsillou Eleni, Karagiannis Tom C, Jandeleit-Dahm Karin, Ma Ronald C W, Huang Yu, Chan Juliana C N, Cooper Mark E, El-Osta Assam

An In Silico Investigation of the Pathogenic G151R G Protein-Gated Inwardly Rectifying K(+) Channel 4 Variant to Identify Small Molecule Modulators

利用计算机模拟研究致病性 G151R G 蛋白门控内向整流钾离子通道 4 变体,以鉴定小分子调节剂

Pitsillou, Eleni; Liang, Julia J; Kino, Noa; Lockwood, Jessica L; Hung, Andrew; El-Osta, Assam; AbuMaziad, Asmaa S; Karagiannis, Tom C

Identification of Potential Modulators of a Pathogenic G Protein-Gated Inwardly Rectifying K(+) Channel 4 Mutant: In Silico Investigation in the Context of Drug Discovery for Hypertension

致病性G蛋白门控内向整流钾离子通道4突变体的潜在调节剂的鉴定:高血压药物研发背景下的计算机模拟研究

Pitsillou, Eleni; Logothetis, Alexander N O; Liang, Julia J; El-Osta, Assam; Hung, Andrew; AbuMaziad, Asmaa S; Karagiannis, Tom C

Sulforaphane prevents and reverses allergic airways disease in mice via anti-inflammatory, antioxidant, and epigenetic mechanisms

萝卜硫素通过抗炎、抗氧化和表观遗传机制预防和逆转小鼠过敏性气道疾病。

Royce, Simon G; Licciardi, Paul V; Beh, Raymond C; Bourke, Jane E; Donovan, Chantal; Hung, Andrew; Khurana, Ishant; Liang, Julia J; Maxwell, Scott; Mazarakis, Nadia; Pitsillou, Eleni; Siow, Ya Yun; Snibson, Kenneth J; Tobin, Mark J; Ververis, Katherine; Vongsvivut, Jitraporn; Ziemann, Mark; Samuel, Chrishan S; Tang, Mimi L K; El-Osta, Assam; Karagiannis, Tom C

Investigation of small molecule inhibitors of the SARS-CoV-2 papain-like protease by all-atom microsecond modelling, PELE Monte Carlo simulations, and in vitro activity inhibition

利用全原子微秒建模、PELE蒙特卡罗模拟和体外活性抑制研究SARS-CoV-2木瓜蛋白酶样蛋白酶的小分子抑制剂

Liang, Julia J; Pitsillou, Eleni; Ververis, Katherine; Guallar, Victor; Hung, Andrew; Karagiannis, Tom C

Small molecule interactions with the SARS-CoV-2 main protease: In silico all-atom microsecond MD simulations, PELE Monte Carlo simulations, and determination of in vitro activity inhibition

小分子与SARS-CoV-2主蛋白酶的相互作用:计算机全原子微秒级分子动力学模拟、PELE蒙特卡罗模拟以及体外活性抑制的测定

Liang, Julia; Pitsillou, Eleni; Ververis, Katherine; Guallar, Victor; Hung, Andrew; Karagiannis, Tom C

The SARS-CoV-2 helicase as a target for antiviral therapy: Identification of potential small molecule inhibitors by in silico modelling

SARS-CoV-2解旋酶作为抗病毒治疗靶点:通过计算机模拟鉴定潜在的小分子抑制剂

Pitsillou, Eleni; Liang, Julia; Hung, Andrew; Karagiannis, Tom C

Inhibition of interferon-stimulated gene 15 and lysine 48-linked ubiquitin binding to the SARS-CoV-2 papain-like protease by small molecules: In silico studies

小分子抑制干扰素刺激基因15和赖氨酸48连接的泛素与SARS-CoV-2木瓜蛋白酶样蛋白酶的结合:计算机模拟研究

Pitsillou, Eleni; Liang, Julia; Hung, Andrew; Karagiannis, Tom C

In silico investigation of potential small molecule inhibitors of the SARS-CoV-2 nsp10-nsp16 methyltransferase complex

利用计算机模拟方法研究SARS-CoV-2 nsp10-nsp16甲基转移酶复合物的潜在小分子抑制剂

Liang, Julia; Pitsillou, Eleni; Burbury, Lucy; Hung, Andrew; Karagiannis, Tom C