日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Efficacy of an XPO1 inhibitor in combination with irinotecan in a preclinical colorectal cancer model

XPO1抑制剂联合伊立替康在临床前结直肠癌模型中的疗效

Lentz, Robert W; Dominguez, Adrian T A; Balmaceda, Nicole Baranda; Arcaroli, John J; Bagby, Stacey M; Binns, Cameron A; Smoots, Stephen G; Jackson, Marilyn M; Macbeth, Morgan; Holmstoen, Tessa; Banerjee, Tapahsama; Whitty, Phaedra A; Yi, S Stephen; Lieu, Christopher H; Messersmith, Wells A; Pitts, Todd M

Pathological findings of immunotherapy-induced nephrotoxicity in a humanized immune system mouse model

人源化免疫系统小鼠模型中免疫疗法诱导肾毒性的病理学发现

Asby, Sarah C; Thompson, Lauren E; Goedken, Michael; Lucia, Scott M; Dominguez, Adrian T; Kar, Adwitiya; Pitts, Todd M; Kiseljak-Vassiliades, Katja; Lang, Julie; Aleksunes, Lauren M; Joy, Melanie S

Phase II Clinical Trial and Preclinical Evaluation of a Novel CD47 Blockade Combination in Refractory Microsatellite-Stable Metastatic Colorectal Cancer

新型CD47阻断联合疗法治疗难治性微卫星稳定型转移性结直肠癌的II期临床试验和临床前评估

Lentz, Robert W; Lang, Julie; Pitts, Todd M; Blatchford, Patrick; Hu, Junxiao; Jordan, Kimberly R; Van Bokhoven, Adrie; Bagby, Stacey M; Dominguez, Adrian T A; Binns, Cameron A; Robinson, Hannah R; Balmaceda, Nicole; Baiyee, Emily; Leal, Alexis D; Kim, Sunnie S; Davis, S Lindsey; Lieu, Christopher H; Wadlow, Raymond C; Spencer, Kristen; Scott, Aaron J; Boland, Patrick M; Hochster, Howard S; Messersmith, Wells A

Potentiating doxorubicin activity through BCL-2 inhibition in p53 wild-type and mutated triple-negative breast cancer.

通过抑制 BCL-2 增强阿霉素在 p53 野生型和突变型三阴性乳腺癌中的活性

Schreiber Anna R, Smoots Stephen G, Jackson Marilyn M, Bagby Stacey M, Dus Evan D, Dominguez Adrian T A, Binns Cameron A, Pitts Todd M, Diamond Jennifer R

Decitabine reverses innate immune gene suppression in rare melanomas

地西他滨可逆转罕见黑色素瘤中的先天免疫基因抑制

MacBeth, Morgan L; Bagby, Stacey M; Borgers, Jessica S W; Turner, Jacqueline A; Anderson, Kelsey C; Whitty, Phaedra A; Hartman, Sarah; Yacob, Beteleham; Rebecca, Vito W; Davila, Eduardo; Pitts, Todd M; Medina, Theresa M; Patel, Sapna P; McCarter, Martin D; Robinson, William A; Tobin, Richard P; Couts, Kasey L

Population-level comparisons of gene regulatory networks modeled on high-throughput single-cell transcriptomics data

基于高通量单细胞转录组学数据构建的基因调控网络群体水平比较

Osorio, Daniel; Capasso, Anna; Eckhardt, S Gail; Giri, Uma; Somma, Alexander; Pitts, Todd M; Lieu, Christopher H; Messersmith, Wells A; Bagby, Stacey M; Singh, Harinder; Das, Jishnu; Sahni, Nidhi; Yi, S Stephen; Kuijjer, Marieke L

A Phase II Study of Potentiation of Pembrolizumab with Binimetinib and Bevacizumab in Refractory Microsatellite-Stable Colorectal Cancer

一项评估帕博利珠单抗联合比美替尼和贝伐珠单抗增强治疗难治性微卫星稳定型结直肠癌的II期研究

Lentz, Robert W; Friedrich, Tyler J; Blatchford, Patrick J; Jordan, Kimberly R; Pitts, Todd M; Robinson, Hannah R; Davis, S Lindsey; Kim, Sunnie S; Leal, Alexis D; Lee, Mathew R; Waring, Meredith R N; Martin, Anne C; Dominguez, Adrian T A; Bagby, Stacey M; Hartman, Sarah J; Eckhardt, S Gail; Messersmith, Wells A; Lieu, Christopher H

Expanding the landscape of oncogenic drivers and treatment options in acral and mucosal melanomas by targeted genomic profiling

通过靶向基因组分析拓展肢端和黏膜黑色素瘤致癌驱动因素和治疗选择的范围

Turner, Jacqueline A; Van Gulick, Robert J; Robinson, William A; Mughal, Tariq; Tobin, Richard P; MacBeth, Morgan L; Holman, Blair; Classon, Anthony; Bagby, Stacey M; Yacob, Betelehem W; Hartman, Sarah J; Silverman, Ian; Vorwald, Victoria M; Gorden, Nicholas; Gonzalez, Rita; Gay, Laurie M; Ali, Siraj M; Benson, Adam; Miller, Vincent A; Ross, Jeffrey S; Pitts, Todd M; Rioth, Matthew J; Lewis, Karl D; Medina, Theresa; McCarter, Martin D; Gonzalez, Rene; Couts, Kasey L

Examination of Wnt signaling as a therapeutic target for pancreatic ductal adenocarcinoma (PDAC) using a pancreatic tumor organoid library (PTOL).

利用胰腺肿瘤类器官库(PTOL)研究Wnt信号通路作为胰腺导管腺癌(PDAC)治疗靶点的作用

Hawkins Hayley J, Yacob Betelehem W, Brown Monica E, Goldstein Brandon R, Arcaroli John J, Bagby Stacey M, Hartman Sarah J, Macbeth Morgan, Goodspeed Andrew, Danhorn Thomas, Lentz Robert W, Lieu Christopher H, Leal Alexis D, Messersmith Wells A, Dempsey Peter J, Pitts Todd M

Pancreatic Ductal Adenocarcinoma Cells Regulate NLRP3 Activation to Generate a Tolerogenic Microenvironment.

胰腺导管腺癌细胞通过调节 NLRP3 激活来产生耐受性微环境

Amo-Aparicio Jesus, Dominguez Adrian, Atif Shaikh M, Dinarello Alberto, Azam Tania, Alula Kibrom M, Piper Miles, Lieu Christopher H, Lentz Robert W, Leal Alexis D, Bagby Stacey M, Messersmith Wells A, Karam Sana D, Dinarello Charles A, Pitts Todd M, Marchetti Carlo