日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The myeloid SRC family kinase HCK regulates breast cancer growth by activating tumor-associated macrophage-led invasion and inhibiting cytotoxic T cell activity

髓系SRC家族激酶HCK通过激活肿瘤相关巨噬细胞介导的侵袭和抑制细胞毒性T细胞活性来调控乳腺癌的生长。

Murrey, Michael W; Poh, Ashleigh R; Steer, James H; Rinaldi, Catherine; Mouchemore, Kellie A; Dwyer, Amy R; Denisenko, Elena; Kuznetsova, Irina; Yeow, Yen; Jones, Matthew E; Hmon, Khaing P W; Muirí, Dáithí Ó; Liu, Ya-Yu; Lin, Weitao; Forrest, Alistair R R; Ellies, Lesley G; Joyce, David A; Ernst, Matthias; Pixley, Fiona J

The role of macrophage migratory behavior in development, homeostasis and tumor invasion

巨噬细胞迁移行为在发育、体内平衡和肿瘤侵袭中的作用

Murrey, Michael W; Ng, Isaac Trinstern; Pixley, Fiona J

Unravelling the role of macrophages in cardiovascular inflammation through imaging: a state-of-the-art review

通过影像学揭示巨噬细胞在心血管炎症中的作用:最新综述

Parry, Reece; Majeed, Kamran; Pixley, Fiona; Hillis, Graham Scott; Francis, Roslyn Jane; Schultz, Carl Johann

Inhibition of the SRC Kinase HCK Impairs STAT3-Dependent Gastric Tumor Growth in Mice

抑制SRC激酶HCK可损害小鼠STAT3依赖性胃肿瘤的生长

Poh, Ashleigh R; Dwyer, Amy R; Eissmann, Moritz F; Chand, Ashwini L; Baloyan, David; Boon, Louis; Murrey, Michael W; Whitehead, Lachlan; O'Brien, Megan; Lowell, Clifford A; Putoczki, Tracy L; Pixley, Fiona J; O'Donoghue, Robert J J; Ernst, Matthias

Macrophage Depletion in Elderly Mice Improves Response to Tumor Immunotherapy, Increases Anti-tumor T Cell Activity and Reduces Treatment-Induced Cachexia

老年小鼠巨噬细胞耗竭可改善肿瘤免疫疗法的疗效,增强抗肿瘤T细胞活性并减轻治疗引起的恶病质

Duong, Lelinh; Radley-Crabb, Hannah G; Gardner, Joanne K; Tomay, Federica; Dye, Danielle E; Grounds, Miranda D; Pixley, Fiona J; Nelson, Delia J; Jackaman, Connie

Promotion of Tumor Invasion by Tumor-Associated Macrophages: The Role of CSF-1-Activated Phosphatidylinositol 3 Kinase and Src Family Kinase Motility Signaling

肿瘤相关巨噬细胞促进肿瘤侵袭:CSF-1激活的磷脂酰肌醇3激酶和Src家族激酶运动信号的作用

Dwyer, Amy R; Greenland, Eloise L; Pixley, Fiona J

Specific inhibition of PI3K p110δ inhibits CSF-1-induced macrophage spreading and invasive capacity

PI3K p110δ 的特异性抑制可抑制 CSF-1 诱导的巨噬细胞扩散和侵袭能力。

Mouchemore, Kellie A; Sampaio, Natalia G; Murrey, Michael W; Stanley, E Richard; Lannutti, Brian J; Pixley, Fiona J

Macrophage Migration and Its Regulation by CSF-1

巨噬细胞迁移及其受CSF-1调控

Pixley, Fiona J

Phosphorylation of CSF-1R Y721 mediates its association with PI3K to regulate macrophage motility and enhancement of tumor cell invasion

CSF-1R Y721 的磷酸化介导其与 PI3K 的结合,从而调节巨噬细胞的运动并增强肿瘤细胞的侵袭能力。

Sampaio, Natalia G; Yu, Wenfeng; Cox, Dianne; Wyckoff, Jeffrey; Condeelis, John; Stanley, E Richard; Pixley, Fiona J

GLEPP1/protein-tyrosine phosphatase phi inhibitors block chemotaxis in vitro and in vivo and improve murine ulcerative colitis.

GLEPP1/蛋白酪氨酸磷酸酶phi抑制剂在体外和体内均可阻断趋化作用,并改善小鼠溃疡性结肠炎

Gobert Rosanna Pescini, van den Eijnden Monique, Szyndralewiez Cedric, Jorand-Lebrun Catherine, Swinnen Dominique, Chen Linfeng, Gillieron Corine, Pixley Fiona, Juillard Pierre, Gerber Patrick, Johnson-Léger Caroline, Halazy Serge, Camps Montserrat, Bombrun Agnes, Shipp Margaret, Vitte Pierre-Alain, Ardissone Vittoria, Ferrandi Chiara, Perrin Dominique, Rommel Christian, Hooft van Huijsduijnen Rob