日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mutant prion protein enhances NMDA receptor activity, activates PKC, and triggers rapid excitotoxicity in mice

突变朊病毒蛋白增强NMDA受体活性,激活蛋白激酶C (PKC),并在小鼠中引发快速兴奋性毒性。

Lin, Joie; Callender, Julia A; Mayfield, Joshua E; McClatchy, Daniel B; Ojeda-Juárez, Daniel; Pourhamzeh, Mahsa; Soldau, Katrin; Kurt, Timothy D; Danque, Garrett A; Khuu, Helen; Ronson, Josephina E; Pizzo, Donald P; Du, Yixing; Gruber, Maxwell A; Sevillano, Alejandro M; Wang, Jin; Orrú, Christina D; Chen, Joy; Funk, Gail; Aguilar-Calvo, Patricia; Aulston, Brent D; Roy, Subhojit; Rho, Jong M; Bui, Jack D; Newton, Alexandra C; Lipton, Stuart A; Caughey, Byron; Patrick, Gentry N; Doré, Kim; Yates, John R 3rd; Sigurdson, Christina J

Multi-omic analysis of meningeal cerebral amyloid angiopathy reveals enrichment of unsubstituted glucosamine and extracellular proteins.

脑膜淀粉样血管病的多组学分析显示未取代的葡萄糖胺和细胞外蛋白富集

Mayfield Joshua E, Rajic Alexander J, Aguilar-Calvo Patricia, Soldau Katrin, Flores Samantha, Lawrence Roger, Choudhury Biwsa, Ghassemian Majid, Pizzo Donald P, Wagner Steven L, Danque Garrett A, Sumowski Paige, Hansen Lawrence A, Goodwill Vanessa, Esko Jeffery D, Sigurdson Christina J

Reliability and modeling of digital histological measurements in Alzheimer's disease neuropathologic change and Lewy body disease.

阿尔茨海默病神经病理学变化和路易体病数字组织学测量的可靠性和建模

Kim Yongya, Andreasson Thea, Vishupad Namitha, Benegal Avani, Pizzo Donald, Hansen Lawrence, Hiniker Annie, Coughlin David

The cryo-EM-delineated mechanism underlying mimicry of CXCR4 agonism enables widespread stem cell neuroprotection in a mouse model of ALS.

冷冻电镜揭示的 CXCR4 激动剂模拟机制能够在 ALS 小鼠模型中实现广泛的干细胞神经保护

Sang Xiaohong, Jiao Haizhan, Meng Qian, Fang Xiong, Sundaram Kartik S, Zhou Jiao, Xu Yan, Alvarado Asuka I W, Nuryyev Ruslan L, Ourenik Jitka, Ourednik Vaclav, Huang Iris S, Liu Xiang, Mei Yuheng, Qian Tingli, Ciechanover Aaron, Pizzo Donald P, Lane Michael A, Zholudeva Lyandysha V, An Jing, Snyder Evan Y, Hu Hongli, Huang Ziwei

Identification of HTRA4 as a Transcriptional Target of p63 in Trophoblast.

鉴定 HTRA4 为滋养层中 p63 的转录靶标

Donohoe Mary E, Morey Robert, Li Yingchun, Pizzo Donald, Kallol Sampada, Cho Hee-Young, Soncin Francesca, Parast Mana M

TDP43 pathology in chronic traumatic encephalopathy retinas.

慢性创伤性脑病视网膜中的TDP43病理

Phansalkar Ragini, Goodwill Vanessa S, Nirschl Jeffrey J, De Lillo Chiara, Choi Jihee, Spurlock Elizabeth, Coughlin David G, Pizzo Donald, Sigurdson Christina J, Hiniker Annie, Alvarez Victor E, Mckee Ann C, Lin Jonathan H

High placental expression of FLT1, LEP, PHYHIP and IL3RA - In persons of African ancestry with severe preeclampsia

非洲裔重度子痫前期患者胎盘中FLT1、LEP、PHYHIP和IL3RA的高表达

Aisagbonhi, Omonigho; Bui, Tony; Nasamran, Chanond A; St Louis, Hailee; Pizzo, Donald; Meads, Morgan; Mulholland, Megan; Magallanes, Celestine; Lamale-Smith, Leah; Laurent, Louise C; Morey, Robert; Jacobs, Marni B; Fisch, Kathleen M; Horii, Mariko

Activation of the Interferon Pathway in Trophoblast Cells Productively Infected with SARS-CoV-2

SARS-CoV-2 感染滋养层细胞后干扰素通路被激活

Kallol, Sampada; Martin-Sancho, Laura; Morey, Robert; Aisagbonhi, Omonigho; Pizzo, Donald; Meads, Morgan; Chanda, Sumit K; Soncin, Francesca

Association of Neurofibrillary Tangle Distribution With Age at Onset-Related Clinical Heterogeneity in Alzheimer Disease: An Autopsy Study.

神经原纤维缠结分布与阿尔茨海默病发病年龄相关临床异质性的关联:一项尸检研究

Smirnov Denis S, Salmon David P, Galasko Douglas, Goodwill Vanessa S, Hansen Lawrence A, Zhao Yu, Edland Steven D, Léger Gabriel C, Peavy Guerry M, Jacobs Diane M, Rissman Robert, Pizzo Donald P, Hiniker Annie

TDP-43 Pathology Exacerbates Cognitive Decline in Primary Age-Related Tauopathy.

TDP-43 病理加剧原发性年龄相关性 Tau 蛋白病患者的认知能力下降

Smirnov Denis S, Salmon David P, Galasko Douglas, Edland Steven D, Pizzo Donald P, Goodwill Vanessa, Hiniker Annie