日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Intraventricular mass in a 49-year-old male

一名49岁男性脑室内肿块

Zuraski, Connor R; Pizzo, Donald P; Schulte, Jessica D; Goodwill, Vanessa S

Mutant prion protein enhances NMDA receptor activity, activates PKC, and triggers rapid excitotoxicity in mice

突变朊病毒蛋白增强NMDA受体活性,激活蛋白激酶C (PKC),并在小鼠中引发快速兴奋性毒性。

Lin, Joie; Callender, Julia A; Mayfield, Joshua E; McClatchy, Daniel B; Ojeda-Juárez, Daniel; Pourhamzeh, Mahsa; Soldau, Katrin; Kurt, Timothy D; Danque, Garrett A; Khuu, Helen; Ronson, Josephina E; Pizzo, Donald P; Du, Yixing; Gruber, Maxwell A; Sevillano, Alejandro M; Wang, Jin; Orrú, Christina D; Chen, Joy; Funk, Gail; Aguilar-Calvo, Patricia; Aulston, Brent D; Roy, Subhojit; Rho, Jong M; Bui, Jack D; Newton, Alexandra C; Lipton, Stuart A; Caughey, Byron; Patrick, Gentry N; Doré, Kim; Yates, John R 3rd; Sigurdson, Christina J

BRD2 Bromodomain-Mediated Regulation of Cell State Plasticity Modulates Therapy Response in Glioblastoma

BRD2溴结构域介导的细胞状态可塑性调控调节胶质母细胞瘤的治疗反应

Vadla, Raghavendra; Taylor, Brett; Miyake, Yohei; Lin, Benjamin; Kawauchi, Daisuke; Miki, Shunichiro; Nathwani, Nidhi; Jones, Brandon M; Kaur, Yashpreet; Banerjee, Abhinaba; Pham, Philip; Tsang, Jonathan; Baldwin, Albert; Nathanson, David A; Pizzo, Donald P; Miller, C Ryan; Furnari, Frank B

Multi-omic analysis of meningeal cerebral amyloid angiopathy reveals enrichment of unsubstituted glucosamine and extracellular proteins.

脑膜淀粉样血管病的多组学分析显示未取代的葡萄糖胺和细胞外蛋白富集

Mayfield Joshua E, Rajic Alexander J, Aguilar-Calvo Patricia, Soldau Katrin, Flores Samantha, Lawrence Roger, Choudhury Biwsa, Ghassemian Majid, Pizzo Donald P, Wagner Steven L, Danque Garrett A, Sumowski Paige, Hansen Lawrence A, Goodwill Vanessa, Esko Jeffery D, Sigurdson Christina J

The cryo-EM-delineated mechanism underlying mimicry of CXCR4 agonism enables widespread stem cell neuroprotection in a mouse model of ALS.

冷冻电镜揭示的 CXCR4 激动剂模拟机制能够在 ALS 小鼠模型中实现广泛的干细胞神经保护

Sang Xiaohong, Jiao Haizhan, Meng Qian, Fang Xiong, Sundaram Kartik S, Zhou Jiao, Xu Yan, Alvarado Asuka I W, Nuryyev Ruslan L, Ourenik Jitka, Ourednik Vaclav, Huang Iris S, Liu Xiang, Mei Yuheng, Qian Tingli, Ciechanover Aaron, Pizzo Donald P, Lane Michael A, Zholudeva Lyandysha V, An Jing, Snyder Evan Y, Hu Hongli, Huang Ziwei

Prevalence of Frontotemporal Dementia in Females of 5 Hispanic Families With R159H VCP Multisystem Proteinopathy

5个患有R159H VCP多系统蛋白病的西班牙裔家庭中女性额颞叶痴呆的患病率

Shmara, Alyaa; Gibbs, Liliane; Mahoney, Ryan Patrick; Hurth, Kyle; Goodwill, Vanessa S; Cuber, Alicia; Im, Regina; Pizzo, Donald P; Brown, Jerry; Laukaitis, Christina; Mahajan, Shalini; Kimonis, Virginia

Selective tau seeding assays and isoform-specific antibodies define neuroanatomic distribution of progressive supranuclear palsy pathology arising in Alzheimer's disease

选择性tau蛋白播散试验和亚型特异性抗体可确定阿尔茨海默病中出现的进行性核上性麻痹病理的神经解剖分布

Coughlin, David G; Goodwill, Vanessa S; Standke, Heidi G; Kim, Yongya; Coley, Nicolas; Pizzo, Donald P; Galasko, Douglas; Kraus, Allison; Hiniker, Annie

Association of Neurofibrillary Tangle Distribution With Age at Onset-Related Clinical Heterogeneity in Alzheimer Disease: An Autopsy Study.

神经原纤维缠结分布与阿尔茨海默病发病年龄相关临床异质性的关联:一项尸检研究

Smirnov Denis S, Salmon David P, Galasko Douglas, Goodwill Vanessa S, Hansen Lawrence A, Zhao Yu, Edland Steven D, Léger Gabriel C, Peavy Guerry M, Jacobs Diane M, Rissman Robert, Pizzo Donald P, Hiniker Annie

TDP-43 Pathology Exacerbates Cognitive Decline in Primary Age-Related Tauopathy.

TDP-43 病理加剧原发性年龄相关性 Tau 蛋白病患者的认知能力下降

Smirnov Denis S, Salmon David P, Galasko Douglas, Edland Steven D, Pizzo Donald P, Goodwill Vanessa, Hiniker Annie

Long-standing multiple system atrophy-Parkinsonism with limbic and FTLD-type α-synuclein pathology.

长期多系统萎缩-帕金森综合征伴边缘系统和FTLD型α-突触核蛋白病理

Coughlin David G, Dryden Ian, Goodwill Vanessa S, Pizzo Donald P, Wright Brenton, Lessig Stephanie, Galasko Douglas, MacKenzie Ian R, Hiniker Annie