日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Preclinical Evaluation of the Efficacy of the Cyclin-Dependent Kinase Inhibitor Ribociclib in Combination with Letrozole against Patient-Derived Glioblastoma Cells.

细胞周期蛋白依赖性激酶抑制剂瑞博西尼联合来曲唑治疗患者来源的胶质母细胞瘤细胞的临床前疗效评价。

Gadgil Sidharth N, Karve Aniruddha S, Gudelsky Gary A, Gabani Bhavesh B, Kulkarni Shravani P, Phoenix Timothy N, Medvedovic Mario, Plas David R, Wise-Draper Trisha M, Sengupta Soma, DasGupta Biplab, Yogendran Lalanthica, Desai Pankaj B

BRUCE liver-KO enhances MASLD/MASH development in the steatotic PTEN-KO background by impairing mitochondrial metabolism and activating STAT3.

BRUCE liver-KO 通过损害线粒体代谢和激活 STAT3 来增强脂肪肝 PTEN-KO 背景下的 MASLD/MASH 发展。

Che Lixiao, Stevenson Camille K, Plas David R, Wang Jiang, Du Chunying

CPI203, a BET inhibitor, down-regulates a consistent set of DNA synthesis genes across a wide array of glioblastoma lines

CPI203 是一种 BET 抑制剂,它能下调多种胶质母细胞瘤细胞系中一组一致的 DNA 合成基因。

Garrett, Matthew C; Carnwath, Troy; Albano, Rebecca; Zhuang, Yonghua; Behrmann, Catherine A; Pemberton, Merissa; Barakat, Farah; Lober, Robert; Hoeprich, Mark; Paravati, Anthony; Reed, Marilyn; Spry, Hailey; Woo, Daniel; O'Brien, Eric; VanCauwenbergh, Brett; Perentesis, John; Nasser, Rani; Medvedovic, Mario; Plas, David R

A Review of Approaches to Potentiate the Activity of Temozolomide against Glioblastoma to Overcome Resistance

增强替莫唑胺抗胶质母细胞瘤活性以克服耐药性的方法综述

Karve, Aniruddha S; Desai, Janki M; Gadgil, Sidharth N; Dave, Nimita; Wise-Draper, Trisha M; Gudelsky, Gary A; Phoenix, Timothy N; DasGupta, Biplab; Yogendran, Lalanthica; Sengupta, Soma; Plas, David R; Desai, Pankaj B

Coordinated Targeting of S6K1/2 and AXL Disrupts Pyrimidine Biosynthesis in PTEN-Deficient Glioblastoma

协同靶向 S6K1/2 和 AXL 可破坏 PTEN 缺陷型胶质母细胞瘤中的嘧啶生物合成

Behrmann, Catherine A; Ennis, Kelli N; Sarma, Pranjal; Wetzel, Collin; Clark, Nicholas A; Von Handorf, Kate M; Vallabhapurapu, Subrahmanya; Andreani, Cristina; Reigle, James; Scaglioni, Pier Paolo; Meller, Jarek; Czyzyk-Krzeska, Maria F; Kendler, Ady; Qi, Xiaoyang; Sarkaria, Jann N; Medvedovic, Mario; Sengupta, Soma; Dasgupta, Biplab; Plas, David R

Chromatin structure predicts survival in glioma patients

染色质结构可预测胶质瘤患者的生存期

Garrett, Matthew C; Albano, Rebecca; Carnwath, Troy; Shah, Sanjit; Woo, Daniel; Lamba, Michael; Plas, David R; Paranjpe, Aditi; Roskin, Krishna; Zhao, Chuntao; Lu, Richard

Tobacco smoking induces metabolic reprogramming of renal cell carcinoma

吸烟会诱导肾细胞癌的代谢重编程

Reigle, James; Secic, Dina; Biesiada, Jacek; Wetzel, Collin; Shamsaei, Behrouz; Chu, Johnson; Zang, Yuanwei; Zhang, Xiang; Talbot, Nicholas J; Bischoff, Megan E; Zhang, Yongzhen; Thakar, Charuhas V; Gaitonde, Krishnanath; Sidana, Abhinav; Bui, Hai; Cunningham, John T; Zhang, Qing; Schmidt, Laura S; Linehan, W Marston; Medvedovic, Mario; Plas, David R; Figueroa, Julio A Landero; Meller, Jarek; Czyzyk-Krzeska, Maria F

Molecular and Metabolic Subtypes in Sporadic and Inherited Clear Cell Renal Cell Carcinoma

散发性和遗传性透明细胞肾细胞癌的分子和代谢亚型

Czyzyk-Krzeska, Maria F; Landero Figueroa, Julio A; Gulati, Shuchi; Cunningham, John T; Meller, Jarek; ShamsaeI, Behrouz; Vemuri, Bhargav; Plas, David R

Metabolic subtypes of clear cell renal cell carcinoma defined by tobacco smoking

吸烟导致的透明细胞肾细胞癌代谢亚型

Czyzyk-Krzeska, Maria F; Meller, Jarek; Landero Figueroa, Julio A; Plas, David R; Cunningham, John T

Choreography of methylation: KDM4C histone demethylation enables ALKBH5 m6A RNA demethylation to sustain AML stem cells

甲基化调控:KDM4C组蛋白去甲基化促进ALKBH5 m6A RNA去甲基化,从而维持AML干细胞。

Sarma, Pranjal; Plas, David R