日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Multiple intramolecular triggers converge to preferential G protein coupling in the CB(2)R

多种分子内触发因素汇聚于CB(2)受体中G蛋白的优先偶联。

Morales-Pastor, Adrian; Miljuš, Tamara; Dieguez-Eceolaza, Miguel; Stępniewski, Tomasz Maciej; Ledesma-Martin, Vicente; Heydenreich, Franziska M; Flock, Tilman; Plouffe, Bianca; Le Gouill, Christian; Duchaine, Jean; Sykes, David A; Nicholson, Colin; Koers, Eline J; Guba, Wolfgang; Rufer, Arne C; Grether, Uwe; Bouvier, Michel; Veprintsev, Dmitry B; Selent, Jana

Endosomal chemokine receptor signalosomes regulate central mechanisms underlying cell migration.

内体趋化因子受体信号体调节细胞迁移的核心机制

Hahn Hyunggu, Daly Carole, Little John 4th, Perry-Hauser Nicole A, Flores-Espinoza Emmanuel, Inoue Asuka, Plouffe Bianca, Thomsen Alex R B

Identification of a novel GREMLIN1 uptake pathway in epithelial cells that requires BMP binding.

鉴定出上皮细胞中一种新的 GREMLIN1 摄取途径,该途径需要 BMP 结合。

Gao Zhichun, Gao Yuhan, Dutton Louise R, Suner Melibea Berzosa, Todd Grace, Gipson Gregory R, Brown Connor, Kerr Emma M, Daly Carole, Plouffe Bianca, Dunne Philip D, Malinova Dessislava, Brazil Derek P

Plasma membrane rather than endosomal Gq signaling drives transcriptional activity by the viral chemokine receptor US28 in glioblastoma

在胶质母细胞瘤中,病毒趋化因子受体US28的转录活性是由质膜而非内体Gq信号传导驱动的。

Daly, Carole; Wright, Adam; Heukers, Raimond; McKee, Chloe M; Coll, Rebecca C; Evergren, Emma; Smit, Martine J; Thomsen, Alex R B; Plouffe, Bianca

Exploring an Intracellular Allosteric Site of CC-Chemokine Receptor 4 from 3D Models, Probe Simulations, and Mutagenesis

利用三维模型、探针模拟和诱变技术探索CC趋化因子受体4的细胞内变构位点

Ding, Tianyi; Guseinov, Abdul-Akim; Milligan, Graeme; Plouffe, Bianca; Tikhonova, Irina G

β-Arrestin-dependent and -independent endosomal G protein activation by the vasopressin type 2 receptor

血管加压素2型受体介导的β-arrestin依赖性和非依赖性内体G蛋白激活

Daly, Carole; Guseinov, Akim Abdul; Hahn, Hyunggu; Wright, Adam; Tikhonova, Irina G; Thomsen, Alex Rojas Bie; Plouffe, Bianca

Structural Elements Directing G Proteins and β-Arrestin Interactions with the Human Melatonin Type 2 Receptor Revealed by Natural Variants

天然变异体揭示了指导 G 蛋白和 β-arrestin 与人类褪黑素 2 型受体相互作用的结构元件

Plouffe, Bianca; Karamitri, Angeliki; Flock, Tilman; Gallion, Jonathan M; Houston, Shane; Daly, Carole A; Bonnefond, Amélie; Guillaume, Jean-Luc; Le Gouill, Christian; Froguel, Phillipe; Lichtarge, Olivier; Deupi, Xavier; Jockers, Ralf; Bouvier, Michel

The constitutive activity of the viral-encoded G protein-coupled receptor US28 supports a complex signalling network contributing to cancer development

病毒编码的G蛋白偶联受体US28的组成性活性支持着一个复杂的信号网络,该网络有助于癌症的发生发展。

Daly, Carole A; Smit, Martine J; Plouffe, Bianca

Emerging Role of Compartmentalized G Protein-Coupled Receptor Signaling in the Cardiovascular Field

区室化G蛋白偶联受体信号传导在心血管领域的新兴作用

Plouffe, Bianca; Thomsen, Alex R B; Irannejad, Roshanak

Translating biased signaling in the ghrelin receptor system into differential in vivo functions

将生长素释放肽受体系统中的偏向性信号传导转化为体内差异性功能

Mende, Franziska; Hundahl, Cecilie; Plouffe, Bianca; Skov, Louise Julie; Sivertsen, Bjørn; Madsen, Andreas Nygaard; Lückmann, Michael; Diep, Thi Ai; Offermanns, Stefan; Frimurer, Thomas Michael; Bouvier, Michel; Holst, Birgitte