日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Androgen receptor splice variant 7 expression levels distinguish AR-mutated from nonmutated metastatic castration-resistant prostate cancers

雄激素受体剪接变体7的表达水平可以区分AR突变型和非突变型转移性去势抵抗性前列腺癌。

Paschalis, Alec; Figueiredo, Ines; Bogdan, Denisa; Lundberg, Arian; Santos, Rita; Gurel, Bora; Taha, Tarek; Longoria, Ossian; Ferreira, Ana; Bertan, Claudia; Brittain, Nicholas; Nelson, Ryan; Walker, Laura; Neeb, Antje; Welti, Jonathan; Yuan, Wei; Mitsopoulos, Costas; Plymate, Stephen R; Haffner, Michael C; Sowalsky, Adam G; Carreira, Suzanne; Sharp, Adam; Gaughan, Luke; de Bono, Johann

Suppression of de novo lipogenesis and dietary PUFA supplementation inhibit prostate cancer progression

抑制从头脂肪生成和补充膳食多不饱和脂肪酸可抑制前列腺癌进展。

Rodrigues, Silvia D; Fidalgo Ribeiro, Caroline; Fanelli, Giuseppe N; Ferreira Teixeira, Isadora; Pakula, Hubert; Nuzzo, Pier Vitale; Pederzoli, Filippo; Socciarelli, Fabio; Bleve, Sara; Jiang, Jeanne; Dehairs, Jonas; Tamarindo, Guilherme Henrique; Zadra, Giorgia; Butler, Lisa M; Plymate, Stephen R; Goodrich, David W; Swinnen, Johannes V; Nanus, David M; Loda, Massimo

A Compound that Inhibits Glycolysis in Prostate Cancer Controls Growth of Advanced Prostate Cancer

一种抑制前列腺癌糖酵解的化合物可控制晚期前列腺癌的生长

Uo, Takuma; Ojo, Kayode K; Sprenger, Cynthia C; Epilepsia, Kathryn Soriano; Perera, B Gayani K; Damodarasamy, Mamatha; Sun, Shihua; Kim, Soojin; Hogan, Hannah H; Hulverson, Matthew A; Choi, Ryan; Whitman, Grant R; Barrett, Lynn K; Michaels, Samantha A; Xu, Linda H; Sun, Vicky L; Arnold, Samuel L M; Pang, Haley J; Nguyen, Matthew M; Vigil, Anna-Lena B G; Kamat, Varun; Sullivan, Lucas B; Sweet, Ian R; Vidadala, Ram; Maly, Dustin J; Van Voorhis, Wesley C; Plymate, Stephen R

Starving lethal prostate cancer by targeting heat shock proteins and glycolytic enzymes

通过靶向热休克蛋白和糖酵解酶来抑制致命的前列腺癌细胞

Plymate, Stephen R; Sprenger, Cynthia; Haffner, Michael C

Druggable Metabolic Vulnerabilities Are Exposed and Masked during Progression to Castration Resistant Prostate Cancer

在去势抵抗性前列腺癌的进展过程中,可药物靶向的代谢脆弱性会暴露出来,但同时也会被掩盖。

Choi, Stephen Y C; Ribeiro, Caroline Fidalgo; Wang, Yuzhuo; Loda, Massimo; Plymate, Stephen R; Uo, Takuma

Selective androgen receptor modulators activate the canonical prostate cancer androgen receptor program and repress cancer growth

选择性雄激素受体调节剂激活经典的前列腺癌雄激素受体程序并抑制癌细胞生长。

Nyquist, Michael D; Ang, Lisa S; Corella, Alexandra; Coleman, Ilsa M; Meers, Michael P; Christiani, Anthony J; Pierce, Cordell; Janssens, Derek H; Meade, Hannah E; Bose, Arnab; Brady, Lauren; Howard, Timothy; De Sarkar, Navonil; Frank, Sander B; Dumpit, Ruth F; Dalton, James T; Corey, Eva; Plymate, Stephen R; Haffner, Michael C; Mostaghel, Elahe A; Nelson, Peter S

AR-V7 biomarker testing for primary prostate cancer: The ongoing challenge of analytical validation and clinical qualification

AR-V7生物标志物检测在原发性前列腺癌中的应用:分析验证和临床验证面临的持续挑战

Sowalsky, Adam G; Sharp, Adam; Trostel, Shana Y; de Bono, Johann S; Plymate, Stephen R

Antitumor Activity of the IGF-1/IGF-2-Neutralizing Antibody Xentuzumab (BI 836845) in Combination with Enzalutamide in Prostate Cancer Models

IGF-1/IGF-2中和抗体Xentuzumab(BI 836845)联合恩扎卢胺在前列腺癌模型中的抗肿瘤活性

Weyer-Czernilofsky, Ulrike; Hofmann, Marco H; Friedbichler, Katrin; Baumgartinger, Rosa; Adam, Paul J; Solca, Flavio; Kraut, Norbert; Nguyen, Holly M; Corey, Eva; Liu, Gang; Sprenger, Cynthia C; Plymate, Stephen R; Bogenrieder, Thomas

Androgen Receptor Signaling and Metabolic and Cellular Plasticity During Progression to Castration Resistant Prostate Cancer

去势抵抗性前列腺癌进展过程中雄激素受体信号传导、代谢和细胞可塑性

Uo, Takuma; Sprenger, Cynthia C; Plymate, Stephen R

The androgen receptor regulates a druggable translational regulon in advanced prostate cancer

雄激素受体调控晚期前列腺癌中一个可药物靶向的翻译调控子

Liu, Yuzhen; Horn, Jessie L; Banda, Kalyan; Goodman, Asha Z; Lim, Yiting; Jana, Sujata; Arora, Sonali; Germanos, Alexandre A; Wen, Lexiaochuan; Hardin, William R; Yang, Yu C; Coleman, Ilsa M; Tharakan, Robin G; Cai, Elise Y; Uo, Takuma; Pillai, Smitha P S; Corey, Eva; Morrissey, Colm; Chen, Yu; Carver, Brett S; Plymate, Stephen R; Beronja, Slobodan; Nelson, Peter S; Hsieh, Andrew C