Bromodomain inhibitor i-BET858 triggers a unique transcriptional response coupled to enhanced DNA damage, cell cycle arrest and apoptosis in high-grade ovarian carcinoma cells
溴结构域抑制剂 i-BET858 可触发独特的转录反应，并伴有高级别卵巢癌细胞中 DNA 损伤增强、细胞周期停滞和细胞凋亡
期刊:Clinical Epigenetics
影响因子:
doi:10.1186/s13148-023-01477-x
Marcos Quintela, David W James, Agne Pociute, Lydia Powell, Kadie Edwards, Zoe Coombes, Jetzabel Garcia, Neil Garton, Nagindra Das, Kerryn Lutchman-Singh, Lavinia Margarit, Amy L Beynon, Inmaculada Rioja, Rab K Prinjha, Nicola R Harker, Deyarina Gonzalez, R Steven Conlan, Lewis W Francis
信号转导
细胞生物学
肿瘤
卵巢癌
肿瘤细胞
ChIP
Apoptosis
Human
G3P
