Podust Larissa相关文献与解析，生知库 | 链接生命科学的每一步

Sharma, Vandna; Madia, Valentina Noemi; Tudino, Valeria; Nguyen, Jennifer V; Debnath, Anjan; Messore, Antonella; Ialongo, Davide; Patacchini, Elisa; Palenca, Irene; Basili Franzin, Silvia; Seguella, Luisa; Esposito, Giuseppe; Petrucci, Rita; Di Matteo, Paola; Bortolami, Martina; Saccoliti, Francesco; Di Santo, Roberto; Scipione, Luigi; Costi, Roberta; Podust, Larissa M

发表日期：2023

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Essential Role of Loop Dynamics in Type II NRPS Biomolecular Recognition

环动力学在II型NRPS生物分子识别中的关键作用

期刊:ACS Chemical Biology

影响因子:3.8

doi:10.1021/acschembio.2c00523

Corpuz, Joshua C; Patel, Ashay; Davis, Tony D; Podust, Larissa M; McCammon, J Andrew; Burkart, Michael D

发表日期：2022

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The Antifungal Drug Isavuconazole Is both Amebicidal and Cysticidal against Acanthamoeba castellanii

抗真菌药物伊沙康唑对棘阿米巴既有杀阿米巴原虫作用，也有杀囊肿作用。

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.5

doi:10.1128/AAC.02223-19

Shing, Brian; Singh, Seema; Podust, Larissa M; McKerrow, James H; Debnath, Anjan

微生物学

发表日期：2020

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Short-lived neutral FMN and FAD semiquinones are transient intermediates in cryo-reduced yeast NADPH-cytochrome P450 reductase

短寿命的中性FMN和FAD半醌是低温还原酵母NADPH-细胞色素P450还原酶中的瞬态中间体。

期刊:Archives of Biochemistry and Biophysics

影响因子:3

doi:10.1016/j.abb.2019.108080

Davydov, Roman M; Jennings, Gareth; Hoffman, Brian M; Podust, Larissa M

细胞生物学

发表日期：2019

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Rapid Chagas Disease Drug Target Discovery Using Directed Evolution in Drug-Sensitive Yeast

利用药物敏感酵母的定向进化快速发现恰加斯病药物靶点

期刊:ACS Chemical Biology

影响因子:3.8

doi:10.1021/acschembio.6b01037

Ottilie, Sabine; Goldgof, Gregory M; Calvet, Claudia Magalhaes; Jennings, Gareth K; LaMonte, Greg; Schenken, Jake; Vigil, Edgar; Kumar, Prianka; McCall, Laura-Isobel; Lopes, Eduardo Soares Constantino; Gunawan, Felicia; Yang, Jennifer; Suzuki, Yo; Siqueira-Neto, Jair L; McKerrow, James H; Amaro, Rommie E; Podust, Larissa M; Durrant, Jacob D; Winzeler, Elizabeth A

Yeast

发表日期：2017

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4-aminopyridyl-based lead compounds targeting CYP51 prevent spontaneous parasite relapse in a chronic model and improve cardiac pathology in an acute model of Trypanosoma cruzi infection

靶向CYP51的4-氨基吡啶类先导化合物可预防慢性模型中的寄生虫自发复发，并改善克氏锥虫感染急性模型中的心脏病理。

期刊:PLoS Neglected Tropical Diseases

影响因子:3.4

doi:10.1371/journal.pntd.0006132

Calvet, Claudia Magalhaes; Choi, Jun Yong; Thomas, Diane; Suzuki, Brian; Hirata, Ken; Lostracco-Johnson, Sharon; de Mesquita, Liliane Batista; Nogueira, Alanderson; Meuser-Batista, Marcelo; Silva, Tatiana Araujo; Siqueira-Neto, Jair Lage; Roush, William R; de Souza Pereira, Mirian Claudia; McKerrow, James H; Podust, Larissa M

Phenotypic, chemical and functional characterization of cyclic nucleotide phosphodiesterase 4 (PDE4) as a potential anthelmintic drug target.

环核苷酸磷酸二酯酶 4 (PDE4) 作为潜在驱虫药物靶点的表型、化学和功能表征

期刊:PLoS Neglected Tropical Diseases

影响因子:3.4

doi:10.1371/journal.pntd.0005680

Long Thavy, Rojo-Arreola Liliana, Shi Da, El-Sakkary Nelly, Jarnagin Kurt, Rock Fernando, Meewan Maliwan, RascÃ³n Alberto A Jr, Lin Lin, Cunningham Katherine A, Lemieux George A, Podust Larissa, Abagyan Ruben, Ashrafi Kaveh, McKerrow James H, Caffrey Conor R

Biochemical and Structural Characterization of MycCI, a Versatile P450 Biocatalyst from the Mycinamicin Biosynthetic Pathway

MycCI（一种来自霉素生物合成途径的多功能P450生物催化剂）的生化和结构表征

期刊:ACS Chemical Biology

影响因子:3.8

doi:10.1021/acschembio.6b00479

DeMars, Matthew D 2nd; Sheng, Fang; Park, Sung Ryeol; Lowell, Andrew N; Podust, Larissa M; Sherman, David H

发表日期：2016

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Correction: The Schistosoma mansoni Cytochrome P450 (CYP3050A1) Is Essential for Worm Survival and Egg Development

更正：曼氏血吸虫细胞色素P450（CYP3050A1）对虫体存活和卵发育至关重要

期刊:PLoS Neglected Tropical Diseases

影响因子:3.4

doi:10.1371/journal.pntd.0004439

Ziniel, Peter D; Karumudi, Bhargava; Barnard, Andrew H; Fisher, Ethan M S; Thatcher, Gregory R J; Podust, Larissa M; Williams, David L

Enzymatic hydroxylation of an unactivated methylene C-H bond guided by molecular dynamics simulations

分子动力学模拟指导下未活化亚甲基CH键的酶促羟基化

期刊:Nature Chemistry

影响因子:20.2

doi:10.1038/nchem.2285

Narayan, Alison R H; Jiménez-Osés, Gonzalo; Liu, Peng; Negretti, Solymar; Zhao, Wanxiang; Gilbert, Michael M; Ramabhadran, Raghunath O; Yang, Yun-Fang; Furan, Lawrence R; Li, Zhe; Podust, Larissa M; Montgomery, John; Houk, K N; Sherman, David H

发表日期：2015

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Miconazole-like Scaffold is a Promising Lead for Naegleria fowleri-Specific CYP51 Inhibitors

咪康唑类骨架是针对福氏耐格里阿米巴原虫的CYP51特异性抑制剂的有前景的先导化合物

Essential Role of Loop Dynamics in Type II NRPS Biomolecular Recognition

环动力学在II型NRPS生物分子识别中的关键作用

The Antifungal Drug Isavuconazole Is both Amebicidal and Cysticidal against Acanthamoeba castellanii

抗真菌药物伊沙康唑对棘阿米巴既有杀阿米巴原虫作用，也有杀囊肿作用。

Short-lived neutral FMN and FAD semiquinones are transient intermediates in cryo-reduced yeast NADPH-cytochrome P450 reductase

短寿命的中性FMN和FAD半醌是低温还原酵母NADPH-细胞色素P450还原酶中的瞬态中间体。

Rapid Chagas Disease Drug Target Discovery Using Directed Evolution in Drug-Sensitive Yeast

利用药物敏感酵母的定向进化快速发现恰加斯病药物靶点

4-aminopyridyl-based lead compounds targeting CYP51 prevent spontaneous parasite relapse in a chronic model and improve cardiac pathology in an acute model of Trypanosoma cruzi infection

靶向CYP51的4-氨基吡啶类先导化合物可预防慢性模型中的寄生虫自发复发，并改善克氏锥虫感染急性模型中的心脏病理。

Phenotypic, chemical and functional characterization of cyclic nucleotide phosphodiesterase 4 (PDE4) as a potential anthelmintic drug target.

环核苷酸磷酸二酯酶 4 (PDE4) 作为潜在驱虫药物靶点的表型、化学和功能表征

Biochemical and Structural Characterization of MycCI, a Versatile P450 Biocatalyst from the Mycinamicin Biosynthetic Pathway

MycCI（一种来自霉素生物合成途径的多功能P450生物催化剂）的生化和结构表征

Correction: The Schistosoma mansoni Cytochrome P450 (CYP3050A1) Is Essential for Worm Survival and Egg Development

更正：曼氏血吸虫细胞色素P450（CYP3050A1）对虫体存活和卵发育至关重要

Enzymatic hydroxylation of an unactivated methylene C-H bond guided by molecular dynamics simulations

分子动力学模拟指导下未活化亚甲基CH键的酶促羟基化