日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Atomoxetine Drug Properties for Repurposing as a Candidate Alzheimer’s Disease Therapeutic Agent

阿托莫西汀的药物特性使其有望成为阿尔茨海默病治疗药物的候选药物

Dammer, Eric B; Read, R; Luis Jimenez Macias, J; Oh, S; Hu, Z; Yin, K; Sele, N; Boon, N; Sing, A; Sloan, S; Yordanov, N Y; Maleki, N; Amiruddin, R; Moawad, A W; Gkampenis, A; Fehringer, P; Umeh, F; Chukwurah, C; Pytlarz, M; Ivory, M; Petrovic, B; Albalooshy, B; Schrickel, E; Memon, F; Cramer, J; Krycia, M; Alotaibi, A; Jakovljevic, M; Guelen, M S; Ghonim, M; Ghonim, M; Page, N; Mhana, S; Baid, U; Lohmann, P; Bakas, S; Aboian, M; Babovic-Vuksanovic, D; Moertel, C L; Shuhaiber, H H; Viskochil, D; Sidhu, A; Meade, J; Hirbe, A C; Weintraub, L; Langseth, A J; Weber, M D; Lokku, A; Hajjar, F M; Antony, R; Schiff, D; Raslan, A M; Nevel, K; Gershon, T R; Demsey, Laura L; Burch, Danielle; Lin, Evan; Quach, Diana; Podvin, Sonia; Boyarko, Ben; Levey, Allan I; Weinshenker, David; Edland, Steven; Galasko, Douglas; Jacobs, Heidi; Bang, Anne; Neil, Ashley; Silverman, James; Feldman, Howard H; Hook, Vivian

Activation of Cytosolic Cathepsin B Activity in the Brain by Traumatic Brain Injury and Inhibition by the Neutral pH Selective Inhibitor Probe Z-Arg-Lys-AOMK

创伤性脑损伤激活脑内胞质组织蛋白酶B活性,而中性pH选择性抑制剂探针Z-Arg-Lys-AOMK抑制该活性

Podvin, Sonia; Florio, Jazmin; Spencer, Brian; Mante, Michael; Guzman, Estefani; Arias, Carlos; Mosier, Charles; Phan, Von V; Yoon, Michael C; Almaliti, Jehad; O'Donoghue, Anthony J; Gerwick, William H; Rissman, Robert A; Hook, Vivian

Neutral pH-Selective Inhibition of Cytosolic Cathepsin B: A Novel Drug Targeting Strategy for Traumatic Brain Injury and Alzheimer's Disease

中性pH选择性抑制胞质组织蛋白酶B:一种治疗创伤性脑损伤和阿尔茨海默病的新型药物靶向策略

Hook, Vivian; Podvin, Sonia; Yoon, Michael C; Phan, Von V; Florio, Jazmin; Spencer, Brian; Mosier, Charles; Cheng, Adeline; Ahuett, Sarah; Almaliti, Jehad; Gerwick, William H; Rissman, Robert A; O'Donoghue, Anthony J

Regulation of granin neuropeptide gene expression in human brain during development

发育过程中人脑中颗粒蛋白神经肽基因表达的调控

Demsey, Laura L; Podvin, Sonia; Hook, Vivian

Atomoxetine Drug Properties for Repurposing as a Candidate Alzheimer's Disease Therapeutic Agent

阿托莫西汀的药物特性使其有望成为阿尔茨海默病治疗药物的候选药物

Demsey, Laura L; Burch, Danielle; Lin, Evan; Quach, Diana; Podvin, Sonia; Boyarko, Ben; Levey, Allan I; Weinshenker, David; Edland, Steven; Galasko, Douglas; Jacobs, Heidi; Bang, Anne; Neil, Ashley; Silverman, James; Feldman, Howard H; Hook, Vivian

Dysregulation of huntingtin interacting protein networks in human juvenile Huntington's disease brain

人类青少年亨廷顿病脑中亨廷顿蛋白相互作用蛋白网络的失调

Podvin, Sonia; Rosenthal, Brin; Mosier, Charles; Wei, Enlin; Fisch, Kathleen M; Hook, Vivian

Challenges and Opportunities for Consideration of Efavirenz Drug Repurposing for Alzheimer's Disease Therapeutics

将依非韦伦药物重新用于阿尔茨海默病治疗的挑战与机遇

Boyarko, Ben; Podvin, Sonia; Greenberg, Barry; Arnold, Steven; Juanes, Almudena Maroto; van der Kant, Rik; Goldstein, Lawrence; Momper, Jeremiah D; Bang, Anne; Silverman, James; Feldman, Howard H; Hook, Vivian

Evaluation of bumetanide as a potential therapeutic agent for Alzheimer's disease

评估布美他尼作为阿尔茨海默病潜在治疗药物的疗效

Boyarko, Ben; Podvin, Sonia; Greenberg, Barry; Momper, Jeremiah D; Huang, Yadong; Gerwick, William H; Bang, Anne G; Quinti, Luisa; Griciuc, Ana; Kim, Doo Yeon; Tanzi, Rudolph E; Feldman, Howard H; Hook, Vivian

Emerging evidence for dysregulated proteome cargoes of tau-propagating extracellular vesicles driven by familial mutations of tau and presenilin

越来越多的证据表明,tau蛋白和早老素的家族性突变导致tau蛋白传播的细胞外囊泡的蛋白质组货物失调。

Hook, Vivian; Podvin, Sonia; Mosier, Charles; Boyarko, Ben; Seyffert, Laura; Stringer, Haley; Rissman, Robert A

Mutant Huntingtin Protein Interaction Map Implicates Dysregulation of Multiple Cellular Pathways in Neurodegeneration of Huntington's Disease

突变亨廷顿蛋白相互作用图谱揭示亨廷顿病神经退行性变中多种细胞通路失调的机制

Podvin, Sonia; Rosenthal, Sara Brin; Poon, William; Wei, Enlin; Fisch, Kathleen M; Hook, Vivian