日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Flecainide sensitizes conduction to hyponatremia through an ephaptic mechanism

氟卡尼通过突触机制增强低钠血症对神经传导的敏感性。

Adams, William P; Hoeker, Gregory S; Poelzing, Steven

Dissecting Gap Junctional and Ephaptic Contributions to Electrical Conduction in a Novel Cardiomyocyte Pair Model

利用新型心肌细胞对模型解析间隙连接和电突触对电传导的贡献

Wu, Xiaobo; Swanger, Sharon A; Meier, Linnea Elisabeth Bornkast; Dennison, Clare L; Weinberg, Seth H; Poelzing, Steven; Gourdie, Robert G

Age-Associated Perinexal Narrowing Masks Consequences of Sodium Channel Gain of Function in Guinea Pig Hearts

年龄相关性心包狭窄掩盖了豚鼠心脏钠通道功能获得性改变的后果

Wu, Xiaobo; King, David Ryan; Hoeker, Gregory S; Wan, Xiaoping; Deschenes, Isabelle; Johnstone, Scott R; Gourdie, Robert G; Weinberg, Seth H; Poelzing, Steven

Sequence-Dependent Repolarization Is Modulated by Endogenous Action Potential Duration Gradients Rather Than Electrical Coupling in Ventricular Myocardium

心室肌中序列依赖性复极化受内源性动作电位时程梯度而非电耦合调节

Blair, Grace A; Depman, Madeline; Adams, William P; Maisonneuve, Rowan O; Hoeker, Gregory S; Weinberg, Seth H; Poelzing, Steve

Age-dependent remodeling of the sciatic proteome in 5xFAD mice can be attenuated by exercise or donepezil treatment to maintain neuromuscular function

在5xFAD小鼠中,坐骨神经蛋白质组的年龄依赖性重塑可通过运动或多奈哌齐治疗来减轻,从而维持神经肌肉功能。

Brisendine, Matthew H; Nieves-Esparcia, Dijanira Q; Willoughby, Orion S; Brown, John R; Braxton, Daniel S; Henry, Shelby N; McCoin, Collin; Thyfault, John P; Morris, Jill K; Poelzing, Steven; Grange, Robert W; Najt, Charles P; Drake, Joshua C

Hypernatremia Enhances Transient Outward Potassium and Late Sodium Currents in a Mouse Model of Long QT Syndrome Type 3

高钠血症增强长QT综合征3型小鼠模型中的瞬时外向钾电流和晚期钠电流

Wu, Xiaobo; Swanger, Sharon A; Hoeker, Gregory S; Maisonneuve, Rowan; Carmeliet, Peter; Gourdie, Robert G; Weinberg, Seth H; Poelzing, Steven

Acute Adenoviral Infection Elicits an Arrhythmogenic Substrate Prior to Myocarditis

急性腺病毒感染在心肌炎发生前即可诱发心律失常。

Padget, Rachel L; Zeitz, Michael J; Blair, Grace A; Wu, Xiaobo; North, Michael D; Tanenbaum, Mira T; Stanley, Kari E; Phillips, Chelsea M; King, D Ryan; Lamouille, Samy; Gourdie, Robert G; Hoeker, Gregory S; Swanger, Sharon A; Poelzing, Steven; Smyth, James W

Development and characterization of the mode-of-action of inhibitory and agonist peptides targeting the voltage-gated sodium channel SCN1B beta-subunit

开发和表征靶向电压门控钠通道SCN1B β亚基的抑制肽和激动肽的作用机制

Williams, Zachary J; Alvarez-Laviada, Anita; Hoagland, Daniel; Jourdan, L Jane; Poelzing, Steven; Gorelik, Julia; Gourdie, Robert G

Mannitol and hyponatremia regulate cardiac ventricular conduction in the context of sodium channel loss of function

甘露醇和低钠血症在钠通道功能丧失的情况下调节心室传导

Grace A Blair, Xiaobo Wu, Chandra Bain, Mark Warren, Gregory S Hoeker, Steven Poelzing

Neuromuscular Dysfunction Precedes Cognitive Impairment in a Mouse Model of Alzheimer's Disease

在阿尔茨海默病小鼠模型中,神经肌肉功能障碍先于认知障碍出现

Brisendine, Matthew H; Nichenko, Anna S; Bandara, Aloka B; Willoughby, Orion S; Amiri, Niloufar; Weingrad, Zach; Specht, Kalyn S; Bond, Jacob M; Addington, Adele; Jones, Ronald G 3rd; Murach, Kevin A; Poelzing, Steven; Craige, Siobhan M; Grange, Robert W; Drake, Joshua C