日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

AMPK agonism optimizes the in vivo activation and antileukemic efficacy of chimeric antigen receptor T cells.

AMPK激动剂可优化嵌合抗原受体T细胞的体内激活和抗白血病功效。

Braverman Erica, Qin Mengtao, Ampudia-Mesias Elisabet, Schuler Herbert Tres, Brown Harrison, Murdych Lukas, Titus Ann, MacLean Allison, Kanagala Bhavya, Wittmann Christopher, Ramgopal Archana, Kemp Felicia, Mullet Steven J, Yang Aaron, Poholek Amanda C, Gelhaus Stacy, Byersdorfer Craig

IL-9 and Blimp-1 protects the transcriptional identity of group 2 innate lymphocytes in allergic asthma.

IL-9 和 Blimp-1 保护过敏性哮喘中 2 组固有淋巴细胞的转录特性

Zheng Yibo, Zhang Jinyi, Yang Aaron, He Kun, Creech Arianna, Schwartz Daniella M, Gottschalk Rachel A, Bouladoux Nicolas, Belkaid Yasmine, Poholek Amanda C

A unified network systems approach uncovers a core novel program underlying T follicular helper cell differentiation.

统一的网络系统方法揭示了 T 滤泡辅助细胞分化背后的核心新程序

Omelchenko Alisa A, Rahman Syed A, Viswanadham Vinayak V, Yuen Grace J, Del Rio Estrada Perla M, D'Onofrio Valentino, Chen Yijia, Sun Na, Mattoo Hamid, Varma Chinmay G, Salgado Gonzalo, Nava Maribel S, Ruiz Lady C, Rivera Dafne D, Rios Santiago A, Kasturi Sudhir P, Ribeiro Susan P, Shlomchik Mark J, Poholek Amanda C, Pillai Shiv S, Elsner Rebecca A, Mahajan Vinay S, Das Jishnu

SLIDE: Significant Latent Factor Interaction Discovery and Exploration across biological domains

幻灯片:跨生物学领域的重要潜在因素交互作用的发现与探索

Rahimikollu, Javad; Xiao, Hanxi; Rosengart, AnnaElaine; Rosen, Aaron B I; Tabib, Tracy; Zdinak, Paul M; He, Kun; Bing, Xin; Bunea, Florentina; Wegkamp, Marten; Poholek, Amanda C; Joglekar, Alok V; Lafyatis, Robert A; Das, Jishnu

Spatial microniches of IL-2 combine with IL-10 to drive lung migratory T(H)2 cells in response to inhaled allergen.

IL-2 的空间微环境与 IL-10 结合,驱动肺部迁移性 T(H)2 细胞响应吸入的过敏原

He Kun, Xiao Hanxi, MacDonald William A, Mehta Isha, Kishore Akash, Vincent Augusta, Xu Zhongli, Ray Anuradha, Chen Wei, Weaver Casey T, Lambrecht Bart N, Das Jishnu, Poholek Amanda C

Innovative super-resolution in spatial transcriptomics: a transformer model exploiting histology images and spatial gene expression

空间转录组学中的创新超分辨率技术:利用组织学图像和空间基因表达的Transformer模型

Zhao, Chongyue; Xu, Zhongli; Wang, Xinjun; Tao, Shiyue; MacDonald, William A; He, Kun; Poholek, Amanda C; Chen, Kong; Huang, Heng; Chen, Wei

Systems immunology approaches to study T cells in health and disease

利用系统免疫学方法研究健康和疾病状态下的T细胞

Yang, Aaron; Poholek, Amanda C

Regulation and Immunotherapeutic Targeting of the Epigenome in Exhausted CD8 T Cell Responses

耗竭CD8 T细胞反应中表观基因组的调控和免疫治疗靶向

Ford, B Rhodes; Poholek, Amanda C

Tissue-Specific Contributions to Control of T Cell Immunity

组织特异性对T细胞免疫控制的贡献

Poholek, Amanda C

Blimp-1 is essential for allergen-induced asthma and Th2 cell development in the lung

Blimp-1对于过敏原诱发的哮喘和肺部Th2细胞的发育至关重要

He, Kun; Hettinga, Angela; Kale, Sagar Laxman; Hu, Sanmei; Xie, Markus M; Dent, Alexander L; Ray, Anuradha; Poholek, Amanda C