日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cryo-EM structures and binding of mouse and human ACE2 to SARS-CoV-2 variants of concern indicate that mutations enabling immune escape could expand host range

冷冻电镜结构分析表明,小鼠和人ACE2与SARS-CoV-2相关变种的结合情况表明,能够使病毒免疫逃逸的突变可能会扩大其宿主范围。

Ni, Dongchun; Turelli, Priscilla; Beckert, Bertrand; Nazarov, Sergey; Uchikawa, Emiko; Myasnikov, Alexander; Pojer, Florence; Trono, Didier; Stahlberg, Henning; Lau, Kelvin

Author Correction: Internalization and vacuolar targeting of the brassinosteroid hormone receptor BRI1 are regulated by ubiquitination

作者更正:油菜素甾醇激素受体BRI1的内化和液泡靶向受泛素化调控

Martins, Sara; Dohmann, Esther M N; Cayrel, Anne; Johnson, Alexander; Fischer, Wolfgang; Pojer, Florence; Satiat-Jeunemaître, Béatrice; Jaillais, Yvon; Chory, Joanne; Geldner, Niko; Vert, Grégory

Changes in SARS-CoV-2 Spike versus Nucleoprotein Antibody Responses Impact the Estimates of Infections in Population-Based Seroprevalence Studies

SARS-CoV-2刺突蛋白与核蛋白抗体反应的变化会影响基于人群血清流行病学研究中感染人数的估计

Fenwick, Craig; Croxatto, Antony; Coste, Alix T; Pojer, Florence; André, Cyril; Pellaton, Céline; Farina, Alex; Campos, Jérémy; Hacker, David; Lau, Kelvin; Bosch, Berend-Jan; Gonseth Nussle, Semira; Bochud, Murielle; D'Acremont, Valerie; Trono, Didier; Greub, Gilbert; Pantaleo, Giuseppe

High resolution CryoEM structure of the ring-shaped virulence factor EspB from Mycobacterium tuberculosis

结核分枝杆菌环状毒力因子 EspB 的高分辨率冷冻电镜结构

Piton, Jérémie; Pojer, Florence; Wakatsuki, Soichi; Gati, Cornelius; Cole, Stewart T

Structure of EspB, a secreted substrate of the ESX-1 secretion system of Mycobacterium tuberculosis

结核分枝杆菌ESX-1分泌系统分泌底物EspB的结构

Korotkova, Natalia; Piton, Jérémie; Wagner, Jonathan M; Boy-Röttger, Stefanie; Japaridze, Aleksandre; Evans, Timothy J; Cole, Stewart T; Pojer, Florence; Korotkov, Konstantin V

Towards a new combination therapy for tuberculosis with next generation benzothiazinones

探索利用新一代苯并噻嗪类药物治疗结核病的新型联合疗法

Makarov, Vadim; Lechartier, Benoit; Zhang, Ming; Neres, João; van der Sar, Astrid M; Raadsen, Susanne A; Hartkoorn, Ruben C; Ryabova, Olga B; Vocat, Anthony; Decosterd, Laurent A; Widmer, Nicolas; Buclin, Thierry; Bitter, Wilbert; Andries, Koen; Pojer, Florence; Dyson, Paul J; Cole, Stewart T

Functional dissection of intersubunit interactions in the EspR virulence regulator of Mycobacterium tuberculosis

结核分枝杆菌毒力调节因子EspR亚基间相互作用的功能解析

Blasco, Benjamin; Japaridze, Aleksandre; Stenta, Marco; Wicky, Basile I M; Dietler, Giovanni; Dal Peraro, Matteo; Pojer, Florence; Cole, Stewart T

Phenotypic profiling of Mycobacterium tuberculosis EspA point mutants reveals that blockage of ESAT-6 and CFP-10 secretion in vitro does not always correlate with attenuation of virulence

结核分枝杆菌EspA点突变体的表型分析表明,体外ESAT-6和CFP-10分泌的阻断并不总是与毒力减弱相关。

Chen, Jeffrey M; Zhang, Ming; Rybniker, Jan; Basterra, Laetitia; Dhar, Neeraj; Tischler, Anna D; Pojer, Florence; Cole, Stewart T

Evolution of the chalcone-isomerase fold from fatty-acid binding to stereospecific catalysis

查尔酮异构酶折叠的演化:从脂肪酸结合到立体特异性催化

Ngaki, Micheline N; Louie, Gordon V; Philippe, Ryan N; Manning, Gerard; Pojer, Florence; Bowman, Marianne E; Li, Ling; Larsen, Elise; Wurtele, Eve Syrkin; Noel, Joseph P

Towards a new tuberculosis drug: pyridomycin - nature's isoniazid.

迈向新型结核病药物:吡啶霉素——天然异烟肼

Hartkoorn Ruben C, Sala Claudia, Neres João, Pojer Florence, Magnet Sophie, Mukherjee Raju, Uplekar Swapna, Boy-Röttger Stefanie, Altmann Karl-Heinz, Cole Stewart T