日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A comprehensive spatio-cellular map of the human hypothalamus.

人类下丘脑的综合空间细胞图谱

Tadross John A, Steuernagel Lukas, Dowsett Georgina K C, Kentistou Katherine A, Lundh Sofia, Porniece Marta, Klemm Paul, Rainbow Kara, Hvid Henning, Kania Katarzyna, Polex-Wolf Joseph, Knudsen Lotte Bjerre, Pyke Charles, Perry John R B, Lam Brian Y H, Brüning Jens C, Yeo Giles S H

Glp1r-Lepr coexpressing neurons modulate the suppression of food intake and body weight by a GLP-1/leptin dual agonist

共表达 Glp1r-Lepr 的神经元通过 GLP-1/瘦素双重激动剂调节食物摄入和体重的抑制。

Polex-Wolf, Joseph; Deibler, Kristine; Hogendorf, Wouter Frederik Johan; Bau, Sarah; Glendorf, Tine; Stidsen, Carsten Enggaard; Tornøe, Christian Wenzel; Tiantang, Dong; Lundh, Sofia; Pyke, Charles; Tomlinson, Abigail J; Kernodle, Stace; Magrisso, Irwin Jack; Conde-Frieboes, Kilian W; Myers, Martin G Jr; Knudsen, Lotte Bjerre; Seeley, Randy J

Liraglutide Impacts Iron Homeostasis in a Murine Model of Hereditary Hemochromatosis

利拉鲁肽对遗传性血色素沉着症小鼠模型中的铁稳态有影响

Bozadjieva-Kramer, Nadejda; Shin, Jae Hoon; Blok, Neil B; Jain, Chesta; Das, Nupur K; Polex-Wolf, Joseph; Knudsen, Lotte Bjerre; Shah, Yatrik M; Seeley, Randy J

Suppression of food intake by Glp1r/Lepr-coexpressing neurons prevents obesity in mouse models

通过 Glp1r/Lepr 共表达神经元抑制食物摄入可预防小鼠模型中的肥胖

Alan C Rupp, Abigail J Tomlinson, Alison H Affinati, Warren T Yacawych, Allison M Duensing, Cadence True, Sarah R Lindsley, Melissa A Kirigiti, Alexander MacKenzie, Joseph Polex-Wolf, Chien Li, Lotte Bjerre Knudsen, Randy J Seeley, David P Olson, Paul Kievit, Martin G Myers Jr

Semaglutide lowers body weight in rodents via distributed neural pathways

司美格鲁肽通过分散的神经通路降低啮齿动物的体重

Gabery, Sanaz; Salinas, Casper G; Paulsen, Sarah J; Ahnfelt-Rønne, Jonas; Alanentalo, Tomas; Baquero, Arian F; Buckley, Stephen T; Farkas, Erzsébet; Fekete, Csaba; Frederiksen, Klaus S; Helms, Hans Christian C; Jeppesen, Jacob F; John, Linu M; Pyke, Charles; Nøhr, Jane; Lu, Tess T; Polex-Wolf, Joseph; Prevot, Vincent; Raun, Kirsten; Simonsen, Lotte; Sun, Gao; Szilvásy-Szabó, Anett; Willenbrock, Hanni; Secher, Anna; Knudsen, Lotte Bjerre; Hogendorf, Wouter Frederik Johan

Glucose-Dependent Insulinotropic Polypeptide Receptor-Expressing Cells in the Hypothalamus Regulate Food Intake

下丘脑中表达葡萄糖依赖性胰岛素促泌多肽受体的细胞调节食物摄入

Alice E Adriaenssens ,Emma K Biggs ,Tamana Darwish ,John Tadross ,Tanmay Sukthankar ,Milind Girish ,Joseph Polex-Wolf ,Brain Y Lam ,Ilona Zvetkova ,Warren Pan ,Davide Chiarugi ,Giles S H Yeo ,Clemence Blouet ,Fiona M Gribble ,Frank Reimann

Hypothalamic loss of Snord116 recapitulates the hyperphagia of Prader-Willi syndrome

下丘脑Snord116缺失可重现普拉德-威利综合征的过度进食症状。

Polex-Wolf, Joseph; Lam, Brian Yh; Larder, Rachel; Tadross, John; Rimmington, Debra; Bosch, Fàtima; Cenzano, Verónica Jiménez; Ayuso, Eduard; Ma, Marcella Kl; Rainbow, Kara; Coll, Anthony P; O'Rahilly, Stephen; Yeo, Giles Sh

The GLP-1 Analogs Liraglutide and Semaglutide Reduce Atherosclerosis in ApoE-/- and LDLr-/- Mice by a Mechanism That Includes Inflammatory Pathways

GLP-1 类似物利拉鲁肽和索马鲁肽通过包括炎症通路在内的机制减轻 ApoE-/- 和 LDLr-/- 小鼠的动脉粥样硬化

Günaj Rakipovski, Bidda Rolin, Jane Nøhr, Ib Klewe, Klaus S Frederiksen, Robert Augustin, Jacob Hecksher-Sørensen, Camilla Ingvorsen, Joseph Polex-Wolf, Lotte Bjerre Knudsen

Impaired prohormone processing: a grand unified theory for features of Prader-Willi syndrome?

前激素加工障碍:普拉德-威利综合征特征的统一理论?

Polex-Wolf, Joseph; Yeo, Giles S H; O'Rahilly, Stephen

Obesity-associated gene TMEM18 has a role in the central control of appetite and body weight regulation

与肥胖相关的基因TMEM18在中枢神经系统对食欲和体重的调控中发挥作用

Larder, Rachel; Sim, M F Michelle; Gulati, Pawan; Antrobus, Robin; Tung, Y C Loraine; Rimmington, Debra; Ayuso, Eduard; Polex-Wolf, Joseph; Lam, Brian Y H; Dias, Cristina; Logan, Darren W; Virtue, Sam; Bosch, Fatima; Yeo, Giles S H; Saudek, Vladimir; O'Rahilly, Stephen; Coll, Anthony P