日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Population Pharmacokinetic/Pharmacodynamic and Exposure-Response Modeling of Garadacimab in Healthy Volunteers and Patients With Hereditary Angioedema

在健康志愿者和遗传性血管性水肿患者中开展加拉达西单抗的群体药代动力学/药效学和暴露-反应模型研究

Garcia, Ramon; Cheng, Shen; Glassman, Fiona; Sharma, Ankur; De Miguel-Lillo, Bernardo; Wiens, Matthew; Johnston, Curtis; Lawo, John-Philip; Pragst, Ingo; French, Jonathan; Polhamus, Dan; Nandy, Partha

Exposure-safety Markov modeling of ocular adverse events in patient populations treated with tisotumab vedotin

接受tisotumab vedotin治疗的患者群体中眼部不良事件的暴露-安全性马尔可夫模型

Feng, Summer; Gunawan, Rudy; Passey, Chaitali; Voellinger, Jenna; Polhamus, Daniel; Gerritsen, Arnout; O'Day, Christine; Carret, Anne-Sophie; Soumaoro, Ibrahima; Gupta, Manish; Hanley, William D

A Phase I, Open-Label, Fixed Sequence Study to Investigate the Effect of Cytochrome P450 2D6 Inhibition on the Pharmacokinetics of Ulotaront in Healthy Subjects

一项 I 期、开放标签、固定顺序研究,旨在探讨细胞色素 P450 2D6 抑制对健康受试者中 Ulotaront 药代动力学的影响

Tsukada, Hironobu; Chen, Yu-Luan; Xiao, Guangqing; Lennek, Lisa; Milanovic, Snezana M; Worden, MaryAlice; Polhamus, Daniel G; Chiu, Yu-Yuan; Hopkins, Seth C; Galluppi, Gerald R

Population pharmacokinetic analysis of ulotaront in subjects with schizophrenia

乌洛他隆在精神分裂症患者中的群体药代动力学分析

Galluppi, Gerald R; Polhamus, Daniel G; Fisher, Jeannine M; Hopkins, Seth C; Koblan, Kenneth S

Exposure-response analysis of efficacy and safety for pexidartinib in patients with tenosynovial giant cell tumor

pexidartinib治疗腱鞘巨细胞瘤患者的疗效和安全性暴露-反应分析

Yin, Ophelia; Zahir, Hamim; French, Jonathan; Polhamus, Daniel; Wang, Xiaoning; van de Sande, Michiel; Tap, William D; Gelderblom, Hans; Wagner, Andrew J; Healey, John H; Greenberg, Jonathan; Shuster, Dale; Stacchiotti, Silvia

A novel model-based meta-analysis to indirectly estimate the comparative efficacy of two medications: an example using DPP-4 inhibitors, sitagliptin and linagliptin, in treatment of type 2 diabetes mellitus

一种基于模型的新型荟萃分析方法,用于间接评估两种药物的相对疗效:以DPP-4抑制剂西格列汀和利格列汀治疗2型糖尿病为例

Gross, Jorge Luiz; Rogers, James; Polhamus, Daniel; Gillespie, William; Friedrich, Christian; Gong, Yan; Monz, Brigitta Ursula; Patel, Sanjay; Staab, Alexander; Retlich, Silke

Physician practices related to use of BMI-for-age and counseling for childhood obesity prevention: a cross-sectional study

医生在儿童肥胖预防中使用年龄别体重指数和咨询方面的实践:一项横断面研究

Wethington, Holly R; Sherry, Bettylou; Polhamus, Barbara