Association of High Tumor Mutation Burden in Non-Small Cell Lung Cancers With Increased Immune Infiltration and Improved Clinical Outcomes of PD-L1 Blockade Across PD-L1 Expression Levels
非小细胞肺癌中高肿瘤突变负荷与免疫浸润增加和PD-L1阻断治疗在不同PD-L1表达水平下的临床疗效改善相关
期刊:Jama Oncology
影响因子:20.1
doi:10.1001/jamaoncol.2022.1981
Ricciuti, Biagio; Wang, Xinan; Alessi, Joao V; Rizvi, Hira; Mahadevan, Navin R; Li, Yvonne Y; Polio, Andrew; Lindsay, James; Umeton, Renato; Sinha, Rileen; Vokes, Natalie I; Recondo, Gonzalo; Lamberti, Giuseppe; Lawrence, Marissa; Vaz, Victor R; Leonardi, Giulia C; Plodkowski, Andrew J; Gupta, Hersh; Cherniack, Andrew D; Tolstorukov, Michael Y; Sharma, Bijaya; Felt, Kristen D; Gainor, Justin F; Ravi, Arvind; Getz, Gad; Schalper, Kurt A; Henick, Brian; Forde, Patrick; Anagnostou, Valsamo; Jänne, Pasi A; Van Allen, Eliezer M; Nishino, Mizuki; Sholl, Lynette M; Christiani, David C; Lin, Xihong; Rodig, Scott J; Hellmann, Matthew D; Awad, Mark M
