The H3 (K36M) oncohistone inhibits NSD2 to activate a SETD2-dependent antiviral-like immune response in KRAS-driven lung cancer
H3 (K36M) 癌组蛋白抑制 NSD2，从而激活 KRAS 驱动的肺癌中 SETD2 依赖的抗病毒样免疫反应。
期刊:
影响因子:
doi:10.1101/2025.05.25.655971
Gladstein, Amy C; Poltorack, Carson D; Solomon, Akino Mercy Charles; Venkatesh, Sharan; Adler, Keren M; Robertson, Maggie R; Stransky, Stephanie; Irizarry-Negron, Valerie M; Ruiz, Dain A; Freeburg, Nelson F; Sidoli, Simone; Asangani, Irfan A; Shaffer, Sydney M; Feldser, David M
微生物学
RAS
免疫/内分泌
SET
NSD2
肺癌
肿瘤
肿瘤免疫
