Polyak Stephen J相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Combinations of approved oral nucleoside analogues confer potent suppression of alphaviruses in vitro and in vivo

已获批准的口服核苷类似物组合可在体外和体内有效抑制甲病毒。

doi:10.1101/2025.01.24.633564

Verwimp, Sam; Wagoner, Jessica; Arenas, Elijah Gabriela; De Coninck, Lander; Abdelnabi, Rana; Hyde, Jennifer L; Schiffer, Joshua T; White, Judith M; Matthijnssens, Jelle; Neyts, Johan; Polyak, Stephen J; Delang, Leen

发表日期：2025

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A unifying model to explain frequent SARS-CoV-2 rebound after nirmatrelvir treatment and limited prophylactic efficacy

一个统一的模型可以解释尼尔马特雷韦治疗后SARS-CoV-2感染频繁反弹以及预防效果有限的现象。

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-024-49458-9

Esmaeili, Shadisadat; Owens, Katherine; Wagoner, Jessica; Polyak, Stephen J; White, Judith M; Schiffer, Joshua T

发表日期：2024

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Two-way pharmacodynamic modeling of drug combinations and its application to pairs of repurposed Ebola and SARS-CoV-2 agents

药物组合的双向药效学模型及其在埃博拉病毒和SARS-CoV-2再利用药物组合中的应用

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.5

doi:10.1128/aac.01015-23

Xu, Shuang; Esmaeili, Shadisadat; Cardozo-Ojeda, E Fabian; Goyal, Ashish; White, Judith M; Polyak, Stephen J; Schiffer, Joshua T

发表日期：2024

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A unifying model to explain high nirmatrelvir therapeutic efficacy against SARS-CoV-2, despite low post-exposure prophylaxis efficacy and frequent viral rebound

尽管暴露后预防效果低且病毒反弹频繁，但尼尔马特雷韦对SARS-CoV-2仍具有很高的治疗效果，这一现象可以通过统一模型来解释。

doi:10.1101/2023.08.23.23294505

Esmaeili, Shadisadat; Owens, Katherine; Wagoner, Jessica; Polyak, Stephen J; White, Judith M; Schiffer, Joshua T

发表日期：2024

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Latent tuberculosis is associated with heightened levels of pro-and anti-inflammatory cytokines among Kenyan men and women living with HIV on long-term antiretroviral therapy

长期接受抗逆转录病毒治疗的肯尼亚艾滋病毒感染者（包括男性和女性）体内潜伏性结核病与促炎和抗炎细胞因子水平升高有关。

影响因子:3.1

doi:10.1097/QAD.0000000000003523

Temu, Tecla M; Polyak, Stephen J; Wanjalla, Celestine N; Mandela, Nelson Aringo; Dabee, Smritee; Mogaka, Jerusha N; Masyuko, Sarah; Longernecker, Chris; Shakil, Saate; Chohan, Bhavna; Page, Stephanie T; Lacourse, Sylvia M; Gitura, Bernard; Crothers, Kristina; Oyugi, Julius; Jaspan, Heather; Farquhar, Carey; Zifodya, Jerry S

细胞生物学

免疫/内分泌

发表日期：2023

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Combinations of Host- and Virus-Targeting Antiviral Drugs Confer Synergistic Suppression of SARS-CoV-2

宿主靶向抗病毒药物与病毒靶向抗病毒药物联合使用可协同抑制SARS-CoV-2病毒。

期刊:Microbiology Spectrum

影响因子:3.8

doi:10.1128/spectrum.03331-22

Wagoner, Jessica; Herring, Shawn; Hsiang, Tien-Ying; Ianevski, Aleksandr; Biering, Scott B; Xu, Shuang; Hoffmann, Markus; Pöhlmann, Stefan; Gale, Michael Jr; Aittokallio, Tero; Schiffer, Joshua T; White, Judith M; Polyak, Stephen J

发表日期：2022

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Targeting clinical epigenetic reprogramming for chemoprevention of metabolic and viral hepatocellular carcinoma

靶向临床表观遗传重编程以化学预防代谢性和病毒性肝细胞癌

影响因子:25.8

doi:10.1136/gutjnl-2019-318918

Jühling, Frank; Hamdane, Nourdine; Crouchet, Emilie; Li, Shen; El Saghire, Houssein; Mukherji, Atish; Fujiwara, Naoto; Oudot, Marine A; Thumann, Christine; Saviano, Antonio; Roca Suarez, Armando Andres; Goto, Kaku; Masia, Ricard; Sojoodi, Mozhdeh; Arora, Gunisha; Aikata, Hiroshi; Ono, Atsushi; Tabrizian, Parissa; Schwartz, Myron; Polyak, Stephen J; Davidson, Irwin; Schmidl, Christian; Bock, Christoph; Schuster, Catherine; Chayama, Kazuaki; Pessaux, Patrick; Tanabe, Kenneth K; Hoshida, Yujin; Zeisel, Mirjam B; Duong, François Ht; Fuchs, Bryan C; Baumert, Thomas F

细胞生物学

发表日期：2021

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Human Immunodeficiency Virus Is Associated With Higher Levels of Systemic Inflammation Among Kenyan Adults Despite Viral Suppression

尽管病毒受到抑制，但肯尼亚成年人中人类免疫缺陷病毒感染仍与较高的全身炎症水平相关。

期刊:Clinical Infectious Diseases

影响因子:7.3

doi:10.1093/cid/ciaa1650

Masyuko, Sarah J; Page, Stephanie T; Polyak, Stephen J; Kinuthia, John; Osoti, Alfred O; Otieno, Fredrick C; Kibachio, Joseph M; Mogaka, Jerusha N; Macharia, Paul M; Chohan, Bhavna H; Wogner, Jessica; O'Connor, Aidan; Temu, Tecla M; Zifodya, Jerry S; Otedo, Amos; Nakanjako, Damalie; Hughes, James P; Farquhar, Carey

Immunology/Inflammation

免疫/内分泌

发表日期：2021

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Drug Combinations as a First Line of Defense against Coronaviruses and Other Emerging Viruses

药物组合作为对抗冠状病毒和其他新发病毒的第一道防线

影响因子:4.7

doi:10.1128/mbio.03347-21

White, Judith M; Schiffer, Joshua T; Bender Ignacio, Rachel A; Xu, Shuang; Kainov, Denis; Ianevski, Aleksandr; Aittokallio, Tero; Frieman, Matthew; Olinger, Gene G; Polyak, Stephen J

发表日期：2021

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Erratum for Herring et al., "Inhibition of Arenaviruses by Combinations of Orally Available Approved Drugs"

勘误表 Herring 等人，“口服批准药物组合对沙粒病毒的抑制”

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.5

doi:10.1128/AAC.00653-21

Herring, Shawn; Oda, Jessica M; Wagoner, Jessica; Kirchmeier, Delaney; O'Connor, Aidan; Nelson, Elizabeth A; Huang, Qinfeng; Liang, Yuying; DeWald, Lisa Evans; Johansen, Lisa M; Glass, Pamela J; Olinger, Gene G; Ianevski, Aleksandr; Aittokallio, Tero; Paine, Mary F; Fink, Susan L; White, Judith M; Polyak, Stephen J

发表日期：2021

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