日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Integration of palladium-catalyzed C-N coupling into self-encoded libraries for accelerated hit discovery

将钯催化CN偶联反应整合到自编码化合物库中，以加速先导化合物的发现。

期刊:RSC Chemical Biology
影响因子:3.1
doi:10.1039/d5cb00303b
van der Nol, Edith; Luo, Zhenshuo; Gao, Qing Qing; Haupt, Nils Alexander; Böcker, Sebastian; Pomplun, Sebastian
发表日期：2026
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Validation of Digital Cytology for Primary Diagnosis Across a Range of Specimen Types

数字细胞学在多种标本类型中作为初诊手段的验证

期刊:Cytopathology
影响因子:1.1
doi:10.1111/cyt.70063
Mistry, Talisa; Hunter, Harriet; Oukrif, Dahmane; Pomplun, Sabine; Khiroya, Reena; Falzon, Mary; Alan, Tanya; Rodriguez-Justo, Manuel; Levine, Adam P
细胞生物学
发表日期：2026
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ReCHEMbinant stapling enhances intracellular delivery and bioactivity of engineered protein inhibitors

ReCHEMbinant 交联技术可增强工程化蛋白抑制剂的细胞内递送和生物活性。

期刊:
影响因子:
doi:10.1016/j.chempr.2025.102839
Kahler, Jan Pascal; Ellenbroek, Brecht D; van der Noord, Vera E; van de Water, Bob; Pomplun, Sebastian J
细胞生物学
发表日期：2026
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Development of DuoMYC: a synthetic cell penetrant miniprotein that efficiently inhibits the oncogenic transcription factor MYC

DuoMYC的研发：一种能有效抑制致癌转录因子MYC的合成细胞穿透性小蛋白

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.202416082
Ellenbroek, Brecht D; Kahler, Jan Pascal; Arella, Damiano; Lin, Cherina; Jespers, Willem; Züger, Eliane Ann-Katrin; Drukker, Micha; Pomplun, Sebastian J
细胞生物学
肿瘤
肿瘤免疫
MYC
发表日期：2025
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Barcode-free hit discovery from massive libraries enabled by automated small molecule structure annotation

借助自动化小分子结构注释，实现从海量化合物库中无需条形码的先导化合物发现。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-65282-1
van der Nol, Edith; Haupt, Nils Alexander; Gao, Qing Qing; Smit, Benthe A M; Hoffmann, Martin Andre; Engler-Lukajewski, Martin; Ludwig, Marcus; McKenna, Sean; Mata, J Miguel; Béquignon, Olivier J M; van Westen, Gerard; Wendel, Tiemen J; Noordermeer, Sylvie M; Böcker, Sebastian; Pomplun, Sebastian
发表日期：2025
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Clonal evolution and the risk of secondary myeloid neoplasia following chimeric antigen receptor T-cell therapy

嵌合抗原受体T细胞疗法后克隆演变和继发性髓系肿瘤的风险

期刊:Haematologica
影响因子:7.9
doi:10.3324/haematol.2025.287341
Sillito, Francesca; Rampotas, Alexandros; Cheok, Kathleen; Pomplun, Sabine; Baker, Robert; Marafioti, Teresa; O'Reilly, Maeve; Gupta, Rajeev; Kirkwood, Amy A; Roddie, Claire
肿瘤
T细胞
肿瘤免疫
信号转导
T细胞
细胞生物学
免疫/内分泌
发表日期：2025
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Dissecting CD47 expression in lymphoid neoplasms to inform precision immunotherapy with anti-CD47 phagocytic checkpoint blockade.

通过分析淋巴瘤中 CD47 的表达，指导采用抗 CD47 吞噬检查点阻断进行精准免疫治疗

期刊:Haematologica
影响因子:7.9
doi:10.3324/haematol.2024.286864
Marra Andrea, Ramsay Alan, Chamberlain-Keene Samuel, Soares Gabriela, Ponzoni Maurilio, Padmasri Sugerdana, Rodriguez-Justo Manuel, Pomplun Sabine, Proctor Ian, Childerhouse Anna, Muntasser Alsharabati, Cioce Mario, Fazio Vito Michele, Ott German, Piris Miguel, Falini Brunangelo, Marafioti Teresa
免疫/内分泌
CD4
发表日期：2025
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Evaluating BindCraft for Generative Design of High-Affinity Peptides

评估 BindCraft 在高亲和力肽生成设计中的应用

期刊:ACS Chemical Biology
影响因子:3.8
doi:10.1021/acschembio.5c00774
Filius, Mike; Patsos, Thanasis; Minnee, Hugo; Turco, Gianluca; Chong, Henrick E; Liu, Jingming; Gnatzy, Monika; Rooth, Ramon S M; Liu, Andy C H; Ta, Rosa D T; Rijk, Isa H A; Ziani, Safiya; Boxman, Femke J; Pomplun, Sebastian J
发表日期：2025
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AlphaFold-Guided Discovery of an Overlapping MYC/Miz-1 Interface Enables Peptidomimetic Disruption of MYC/MAX

AlphaFold引导发现重叠的MYC/Miz-1界面，从而实现肽模拟物对MYC/MAX的破坏

期刊:ChemMedChem
影响因子:3.4
doi:10.1002/cmdc.202500740
Ellenbroek, Brecht D; Tirtosentono, Amardhiko S S; Pomplun, Sebastian J
MYC
发表日期：2025
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Automated Flow Peptide Synthesis Enables Engineering of Proteins with Stabilized Transient Binding Pockets

自动化流动肽合成技术能够构建具有稳定瞬时结合口袋的蛋白质

期刊:ACS Central Science
影响因子:10.4
doi:10.1021/acscentsci.3c01283
Charalampidou, Anna; Nehls, Thomas; Meyners, Christian; Gandhesiri, Satish; Pomplun, Sebastian; Pentelute, Bradley L; Lermyte, Frederik; Hausch, Felix
发表日期：2024
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