日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Oxidized PDI promotes thrombus formation in oxidative stress

氧化型PDI在氧化应激条件下促进血栓形成。

Yang, Moua; Owegie, Osamede Clinton; Patel, Anika; Kennedy, Quinn Patrick; Flaumenhaft, James T; Chinnaraj, Mathivanan; Ponzar, Nathan; Fulcidor, Emmy M; Rico, Mario C; Bhowmik, Amit; Carroll, Kate S; Handy, Diane E; Loscalzo, Joseph; Essex, David W; Pozzi, Nicola; Flaumenhaft, Robert

Molecular determinants of allosteric modulation of protein disulfide isomerase by small-molecule b'-ligands

小分子β'-配体对蛋白质二硫键异构酶变构调节的分子决定因素

Ponzar, Nathan; Pagotto, Anna; Bandyopadhayay, Srija; Meyers, Marvin J; De Filippis, Vincenzo; Flaumenhaft, Robert; Pozzi, Nicola

Mechanistic basis of activation and inhibition of protein disulfide isomerase by allosteric antithrombotic compounds

变构抗血栓化合物激活和抑制蛋白质二硫键异构酶的机制基础

Ponzar, Nathan; Chinnaraj, Mathivanan; Pagotto, Anna; De Filippis, Vincenzo; Flaumenhaft, Robert; Pozzi, Nicola

Sulfenylation links oxidative stress to protein disulfide isomerase oxidase activity and thrombus formation

亚磺酰化将氧化应激与蛋白质二硫键异构酶氧化酶活性和血栓形成联系起来

Yang, Moua; Chiu, Joyce; Scartelli, Christina; Ponzar, Nathan; Patel, Sachin; Patel, Anika; Ferreira, Renan B; Keyes, Robert F; Carroll, Kate S; Pozzi, Nicola; Hogg, Philip J; Smith, Brian C; Flaumenhaft, Robert

Predicted structure of the hepatitis B virus polymerase reveals an ancient conserved protein fold

乙型肝炎病毒聚合酶的预测结构揭示了一种古老的保守蛋白折叠。

Tajwar, Razia; Bradley, Daniel P; Ponzar, Nathan L; Tavis, John E

Effects of Troponoids on Mitochondrial Function and Cytotoxicity

类托品对线粒体功能和细胞毒性的影响

Bradley, Daniel P; O'Dea, Austin T; Woodson, Molly E; Li, Qilan; Ponzar, Nathan L; Knier, Alaina; Rogers, Bruce L; Murelli, Ryan P; Tavis, John E

Alpha-hydroxytropolones are noncompetitive inhibitors of human RNase H1 that bind to the active site and modulate substrate binding

α-羟基卓酚酮是人核糖核酸酶H1的非竞争性抑制剂,它们与活性位点结合并调节底物结合。

Ponzar, Nathan L; Tajwar, Razia; Pozzi, Nicola; Tavis, John E

A mid-throughput HBV replication inhibition assay capable of detecting ribonuclease H inhibitors

能够检测核糖核酸酶 H 抑制剂的中通量 HBV 复制抑制检测

Qilan Li, Tiffany C Edwards, Nathan L Ponzar, John E Tavis

Shedding light on RNaseH: a promising target for hepatitis B virus (HBV)

揭示 RNaseH 的奥秘:乙型肝炎病毒 (HBV) 的一个有前景的靶点

Edwards, Tiffany C; Ponzar, Nathan L; Tavis, John E

Efficacy of hepatitis B virus ribonuclease H inhibitors, a new class of replication antagonists, in FRG human liver chimeric mice

乙型肝炎病毒核糖核酸酶H抑制剂(一类新型复制拮抗剂)在FRG人肝嵌合小鼠中的疗效

Long, Kelly R; Lomonosova, Elena; Li, Qilan; Ponzar, Nathan L; Villa, Juan A; Touchette, Erin; Rapp, Stephen; Liley, R Matt; Murelli, Ryan P; Grigoryan, Alexandre; Buller, R Mark; Wilson, Lisa; Bial, John; Sagartz, John E; Tavis, John E