Phenotypic Screen with TSC-Deficient Neurons Reveals Heat-Shock Machinery as a Druggable Pathway for mTORC1 and Reduced Cilia
TSC 缺陷型神经元的表型筛选揭示了热休克机制是 mTORC1 和纤毛减少的可用药物途径
期刊:Cell Reports
影响因子:7.5
doi:10.1016/j.celrep.2020.107780
Alessia Di Nardo, Isadora Lenoël, Kellen D Winden, Alina Rühmkorf, Meera E Modi, Lee Barrett, Ebru Ercan-Herbst, Pooja Venugopal, Robert Behne, Carla A M Lopes, Robin J Kleiman, Mónica Bettencourt-Dias, Mustafa Sahin