日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Ucenprubart is an agonistic antibody to CD200R with the potential to treat inflammatory skin disease: preclinical development and a phase 1 clinical study

Ucenprubart 是一种 CD200R 激动性抗体，具有治疗炎症性皮肤病的潜力：临床前开发和 I 期临床研究

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-025-59147-w
Anja Koester ，Derrick R Witcher ，Mark Lee ，Stephen J Demarest ，Scott Potter ，Katie Werle ，Scott Bauer ，Diana Ruiz ，Laurent Malherbe ，Josh Poorbaugh ，Andrew Glasebrook ，Christoph Preuss ，Gourab Datta ，Ziqiao Wang ，Jack Knorr ，David Manner ，Dipak Patel ，Carsten Schmitz ，Paul Klekotka ，Ajay Nirula
炎症/感染
炎症
CD20
CD200
CD2
发表日期：2025
文献求助 收藏

Serum IL-6 and PTX3 predict severe outcome from COVID-19 in ambulatory subjects: Impact for future therapeutic decisions

血清IL-6和PTX3水平可预测门诊COVID-19患者的重症预后：对未来治疗决策的影响

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0324242
Poorbaugh, Josh; Sims, Jonathan T; Zhang, Lin; Chang, Ching-Yun; Higgs, Richard E; Nirula, Ajay; Benschop, Robert J
IL-6
发表日期：2025
文献求助 收藏

Evaluation of plasma IL-21 as a potential biomarker for type 1 diabetes progression

评估血浆IL-21作为1型糖尿病进展潜在生物标志物的价值

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2023.1157265
Schroderus, Anna-Mari; Poorbaugh, Josh; McElyea, Samantha; Beasley, Stephanie; Zhang, Lin; Näntö-Salonen, Kirsti; Rintamäki, Reeta; Pihlajamäki, Jussi; Knip, Mikael; Veijola, Riitta; Toppari, Jorma; Ilonen, Jorma; Benschop, Robert J; Kinnunen, Tuure
糖尿病
IL-21
IL-2
代谢
发表日期：2023
文献求助 收藏

The anti-SARS-CoV-2 monoclonal antibody bamlanivimab minimally affects the endogenous immune response to COVID-19 vaccination

抗SARS-CoV-2单克隆抗体bamlanivimab对COVID-19疫苗的内源性免疫反应影响甚微。

期刊:Science Translational Medicine
影响因子:15.8
doi:10.1126/scitranslmed.abn3041
Robert J Benschop ,Jay L Tuttle ,Lin Zhang ,Josh Poorbaugh ,Nicole L Kallewaard ,Peter Vaillancourt ,Melissa Crisp ,Thi Ngoc Vy Trinh ,Joshua J Freitas ,Stephanie Beasley ,Montanea Daniels ,Natalie Haustrup ,Richard E Higgs ,Ajay Nirula ,Myron S Cohen ,Mary Marovich
SARS-CoV-2
免疫/内分泌
单克隆抗体
发表日期：2022
文献求助 收藏

Longitudinal assessment of systemic steroid therapy on hyperinflammatory endothelial biomarker profiles and serology responses of COVID-19 patients

对 COVID-19 患者进行全身性类固醇治疗后，其高炎症内皮生物标志物谱和血清学反应的纵向评估

期刊:Journal of Translational Medicine
影响因子:7.5
doi:10.1186/s12967-022-03583-5
Sims, Jonathan T; Chang, Ching-Yun; Poorbaugh, Josh; Daniels, Montanea; Beasley, Stephanie L; Zhang, Lin; Rodgers, George H; Lena, Fabio; Lacerenza, Leonardo G; Sposato, Bruno; Dupont, Annabelle; Susen, Sophie; Casalini, Giacomo; Corbellino, Mario; Stebbing, Justin; Krishnan, Venkatesh
炎症/感染
炎症
发表日期：2022
文献求助 收藏

Relationship between gene expression patterns from nasopharyngeal swabs and serum biomarkers in patients hospitalized with COVID-19, following treatment with the neutralizing monoclonal antibody bamlanivimab

接受中和单克隆抗体 bamlanivimab 治疗后，住院 COVID-19 患者鼻咽拭子基因表达模式与血清生物标志物之间的关系

期刊:Journal of Translational Medicine
影响因子:6.1
doi:10.1186/s12967-022-03345-3
Jonathan T Sims, Josh Poorbaugh, Ching-Yun Chang, Timothy R Holzer, Lin Zhang, Sarah M Engle, Stephanie Beasley, Thompson N Doman, Lynn Naughton, Richard E Higgs, Nicole Kallewaard, Robert J Benschop
代谢
免疫
心血管
新冠
Donkey
IgM
发表日期：2022
文献求助 收藏

COVID-19 symptom relationship to antibody response and ACE2 neutralization in recovered health systems employees before and after mRNA BNT162b2 COVID-19 vaccine

新冠肺炎症状与康复医疗系统员工接种mRNA BNT162b2新冠疫苗前后抗体反应和ACE2中和作用的关系

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0273323
Huhn, Gregory; Poorbaugh, Josh; Zhang, Lin; Beasley, Stephanie; Nirula, Ajay; Brothers, Jennifer; Welbel, Sharon; Wilson, James; Gillani, Sheena; Weber, Kathleen M; Morack, Ralph; Keckler, Kody; Benschop, Robert J
肺炎
新冠
炎症
炎症/感染
微生物学
ACE2
发表日期：2022
文献求助 收藏

Endogenous Antibody Responses to SARS-CoV-2 in Patients With Mild or Moderate COVID-19 Who Received Bamlanivimab Alone or Bamlanivimab and Etesevimab Together

接受巴姆拉尼维单抗单药治疗或巴姆拉尼维单抗联合依替塞维单抗治疗的轻度或中度 COVID-19 患者体内针对 SARS-CoV-2 的内源性抗体反应

期刊:Frontiers in Immunology
影响因子:5.7
doi:10.3389/fimmu.2021.790469
Lin Zhang ,Josh Poorbaugh ,Michael Dougan ,Peter Chen ,Robert L Gottlieb ,Gregory Huhn ,Stephanie Beasley ,Montanea Daniels ,Thi Ngoc Vy Trinh ,Melissa Crisp ,Joshua Joaquin Freitas ,Peter Vaillancourt ,Dipak R Patel ,Ajay Nirula ,Nicole L Kallewaard ,Richard E Higgs ,Robert J Benschop
SARS-CoV-2
发表日期：2021
文献求助 收藏

First-in-Human Study of Bamlanivimab in a Randomized Trial of Hospitalized Patients With COVID-19

巴姆拉尼维单抗在新冠肺炎住院患者中的首次人体随机试验

期刊:Clinical Pharmacology & Therapeutics
影响因子:5.5
doi:10.1002/cpt.2405
Chen, Peter; Datta, Gourab; Grace Li, Ying; Chien, Jenny; Price, Karen; Chigutsa, Emmanuel; Brown-Augsburger, Patricia; Poorbaugh, Josh; Fill, Jeffrey; Benschop, Robert J; Rouphael, Nadine; Kay, Ariel; Mulligan, Mark J; Saxena, Amit; Fischer, William A; Dougan, Michael; Klekotka, Paul; Nirula, Ajay; Benson, Charles
肺炎
新冠
Human
微生物学
发表日期：2021
文献求助 收藏