日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Precision analysis of mutant U2AF1 activity reveals deployment of stress granules in myeloid malignancies

对突变型 U2AF1 活性的精确分析揭示了髓系恶性肿瘤中应激颗粒的部署

Giulia Biancon ,Poorval Joshi ,Joshua T Zimmer ,Torben Hunck ,Yimeng Gao ,Mark D Lessard ,Edward Courchaine ,Andrew E S Barentine ,Martin Machyna ,Valentina Botti ,Ashley Qin ,Rana Gbyli ,Amisha Patel ,Yuanbin Song ,Lea Kiefer ,Gabriella Viero ,Nils Neuenkirchen ,Haifan Lin ,Joerg Bewersdorf ,Matthew D Simon ,Karla M Neugebauer ,Toma Tebaldi ,Stephanie Halene

Deconvolution of in vivo protein-RNA contacts using fractionated eCLIP-seq

利用分级eCLIP-seq对体内蛋白质-RNA相互作用进行解卷积

Giulia Biancon ,Emma Busarello ,Poorval Joshi ,Bluma J Lesch ,Stephanie Halene ,Toma Tebaldi

m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development

m6A修饰可阻止造血发育过程中内源性双链RNA的形成和有害的先天免疫反应。

Yimeng Gao ,Radovan Vasic ,Yuanbin Song ,Rhea Teng ,Chengyang Liu ,Rana Gbyli ,Giulia Biancon ,Raman Nelakanti ,Kirsten Lobben ,Eriko Kudo ,Wei Liu ,Anastasia Ardasheva ,Xiaoying Fu ,Xiaman Wang ,Poorval Joshi ,Veronica Lee ,Burak Dura ,Gabriella Viero ,Akiko Iwasaki ,Rong Fan ,Andrew Xiao ,Richard A Flavell ,Hua-Bing Li ,Toma Tebaldi ,Stephanie Halene

SRSF2 mutations drive oncogenesis by activating a global program of aberrant alternative splicing in hematopoietic cells

SRSF2 突变通过激活造血细胞中异常选择性剪接的全局程序来驱动肿瘤发生。

Liang, Yang; Tebaldi, Toma; Rejeski, Kai; Joshi, Poorval; Stefani, Giovanni; Taylor, Ashley; Song, Yuanbin; Vasic, Radovan; Maziarz, Jamie; Balasubramanian, Kunthavai; Ardasheva, Anastasia; Ding, Alicia; Quattrone, Alessandro; Halene, Stephanie

Incorporation of the Kaposi's sarcoma-associated herpesvirus capsid vertex-specific component (CVSC) into self-assembled capsids

将卡波西肉瘤相关疱疹病毒衣壳顶点特异性成分(CVSC)整合到自组装衣壳中

Grzesik, Peter; MacMath, Derek; Henson, Brandon; Prasad, Sanjana; Joshi, Poorval; Desai, Prashant J

Visualization of herpes simplex virus type 1 virions using fluorescent colors

利用荧光染料可视化1型单纯疱疹病毒颗粒

Etienne, Lyns; Joshi, Poorval; Dingle, Laura; Huang, Eugene; Grzesik, Peter; Desai, Prashant J

Ovarian cancer-associated mutations disable catalytic activity of CDK12, a kinase that promotes homologous recombination repair and resistance to cisplatin and poly(ADP-ribose) polymerase inhibitors

卵巢癌相关突变使 CDK12 的催化活性丧失,CDK12 是一种促进同源重组修复和对顺铂和聚(ADP-核糖)聚合酶抑制剂产生耐药性的激酶

Poorval M Joshi, Shari L Sutor, Catherine J Huntoon, Larry M Karnitz