日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

ARID1A regulates DNA repair through chromatin organization and its deficiency triggers DNA damage-mediated anti-tumor immune response

ARID1A通过染色质组织调控DNA修复,其缺陷会引发DNA损伤介导的抗肿瘤免疫反应。

Ali Bakr ,Giuditta Della Corte ,Olivera Veselinov ,Simge Kelekçi ,Mei-Ju May Chen ,Yu-Yu Lin ,Gianluca Sigismondo ,Marika Iacovone ,Alice Cross ,Rabail Syed ,Yunhee Jeong ,Etienne Sollier ,Chun-Shan Liu ,Pavlo Lutsik ,Jeroen Krijgsveld ,Dieter Weichenhan ,Christoph Plass ,Odilia Popanda ,Peter Schmezer

Selective inhibitors of bromodomain BD1 and BD2 of BET proteins modulate radiation-induced profibrotic fibroblast responses

BET 蛋白溴结构域 BD1 和 BD2 的选择性抑制剂调节放射诱导的促纤维化成纤维细胞反应

Chun-Shan Liu, Inmaculada Rioja, Ali Bakr, Marlon R Veldwijk, Elena Sperk, Carsten Herskind, Dieter Weichenhan, Rab K Prinjha, Christoph Plass, Peter Schmezer, Odilia Popanda

ID3 promotes homologous recombination via non-transcriptional and transcriptional mechanisms and its loss confers sensitivity to PARP inhibition

ID3通过非转录和转录机制促进同源重组,其缺失会导致对PARP抑制剂的敏感性。

Ali Bakr ,Joschka Hey ,Gianluca Sigismondo ,Chun-Shan Liu ,Ahmed Sadik ,Ashish Goyal ,Alice Cross ,Ramya Lakshmana Iyer ,Patrick Müller ,Max Trauernicht ,Kersten Breuer ,Pavlo Lutsik ,Christiane A Opitz ,Jeroen Krijgsveld ,Dieter Weichenhan ,Christoph Plass ,Odilia Popanda ,Peter Schmezer

Epigenetic Modulation of Radiation-Induced Diacylglycerol Kinase Alpha Expression Prevents Pro-Fibrotic Fibroblast Response

辐射诱导的二酰甘油激酶α表达的表观遗传调节可预防促纤维化成纤维细胞反应

Chun-Shan Liu, Reka Toth, Ali Bakr, Ashish Goyal, Md Saiful Islam, Kersten Breuer, Anand Mayakonda, Yu-Yu Lin, Peter Stepper, Tomasz P Jurkowski, Marlon R Veldwijk, Elena Sperk, Carsten Herskind, Pavlo Lutsik, Dieter Weichenhan, Christoph Plass, Peter Schmezer, Odilia Popanda

Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability

胰腺腺泡细胞癌的全基因组遗传和表观遗传分析揭示了基因组稳定性的异常

Cornelia Jäkel, Frank Bergmann, Reka Toth, Yassen Assenov, Daniel van der Duin, Oliver Strobel, Thomas Hank, Günter Klöppel, Craig Dorrell, Markus Grompe, Joshua Moss, Yuval Dor, Peter Schirmacher, Christoph Plass, Odilia Popanda, Peter Schmezer

Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients

个体患者数据荟萃分析显示,ATM rs1801516 SNP 与 5456 例乳腺癌和前列腺癌患者放疗后的毒性反应显著相关。

Andreassen, Christian Nicolaj; Rosenstein, Barry S; Kerns, Sarah L; Ostrer, Harry; De Ruysscher, Dirk; Cesaretti, Jamie A; Barnett, Gillian C; Dunning, Alison M; Dorling, Leila; West, Catharine M L; Burnet, Neil G; Elliott, Rebecca; Coles, Charlotte; Hall, Emma; Fachal, Laura; Vega, Ana; Gómez-Caamaño, Antonio; Talbot, Christopher J; Symonds, R Paul; De Ruyck, Kim; Thierens, Hubert; Ost, Piet; Chang-Claude, Jenny; Seibold, Petra; Popanda, Odilia; Overgaard, Marie; Dearnaley, David; Sydes, Matthew R; Azria, David; Koch, Christine Anne; Parliament, Matthew; Blackshaw, Michael; Sia, Michael; Fuentes-Raspall, Maria J; Ramon Y Cajal, Teresa; Barnadas, Agustin; Vesprini, Danny; Gutiérrez-Enríquez, Sara; Mollà, Meritxell; Díez, Orland; Yarnold, John R; Overgaard, Jens; Bentzen, Søren M; Alsner, Jan

Aspirin Reduces Plasma Concentrations of the Oncometabolite 2-Hydroxyglutarate: Results of a Randomized, Double-Blind, Crossover Trial

阿司匹林降低肿瘤代谢物2-羟基戊二酸的血浆浓度:一项随机、双盲、交叉试验的结果

Liesenfeld, David B; Botma, Akke; Habermann, Nina; Toth, Reka; Weigel, Christoph; Popanda, Odilia; Klika, Karel D; Potter, John D; Lampe, Johanna W; Ulrich, Cornelia M

MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma

MYCN和HDAC5转录抑制CD9,从而引发神经母细胞瘤的侵袭和转移。

Fabian, Johannes; Opitz, Desirée; Althoff, Kristina; Lodrini, Marco; Hero, Barbara; Volland, Ruth; Beckers, Anneleen; de Preter, Katleen; Decock, Anneleen; Patil, Nitin; Abba, Mohammed; Kopp-Schneider, Annette; Astrahantseff, Kathy; Wünschel, Jasmin; Pfeil, Sebastian; Ercu, Maria; Künkele, Annette; Hu, Jamie; Thole, Theresa; Schweizer, Leonille; Mechtersheimer, Gunhild; Carter, Daniel; Cheung, Belamy B; Popanda, Odilia; von Deimling, Andreas; Koster, Jan; Versteeg, Rogier; Schwab, Manfred; Marshall, Glenn M; Speleman, Frank; Erb, Ulrike; Zoeller, Margot; Allgayer, Heike; Simon, Thorsten; Fischer, Matthias; Kulozik, Andreas E; Eggert, Angelika; Witt, Olaf; Schulte, Johannes H; Deubzer, Hedwig E

A polymorphism in the base excision repair gene PARP2 is associated with differential prognosis by chemotherapy among postmenopausal breast cancer patients

碱基切除修复基因PARP2的多态性与绝经后乳腺癌患者化疗后的预后差异相关

Seibold, Petra; Schmezer, Peter; Behrens, Sabine; Michailidou, Kyriaki; Bolla, Manjeet K; Wang, Qin; Flesch-Janys, Dieter; Nevanlinna, Heli; Fagerholm, Rainer; Aittomäki, Kristiina; Blomqvist, Carl; Margolin, Sara; Mannermaa, Arto; Kataja, Vesa; Kosma, Veli-Matti; Hartikainen, Jaana M; Lambrechts, Diether; Wildiers, Hans; Kristensen, Vessela; Alnæs, Grethe Grenaker; Nord, Silje; Borresen-Dale, Anne-Lise; Hooning, Maartje J; Hollestelle, Antoinette; Jager, Agnes; Seynaeve, Caroline; Li, Jingmei; Liu, Jianjun; Humphreys, Keith; Dunning, Alison M; Rhenius, Valerie; Shah, Mitul; Kabisch, Maria; Torres, Diana; Ulmer, Hans-Ulrich; Hamann, Ute; Schildkraut, Joellen M; Purrington, Kristen S; Couch, Fergus J; Hall, Per; Pharoah, Paul; Easton, Doug F; Schmidt, Marjanka K; Chang-Claude, Jenny; Popanda, Odilia

Genetic polymorphisms in DNA repair and damage response genes and late normal tissue complications of radiotherapy for breast cancer

DNA修复和损伤反应基因的遗传多态性与乳腺癌放射治疗的晚期正常组织并发症

Chang-Claude, J; Ambrosone, C B; Lilla, C; Kropp, S; Helmbold, I; von Fournier, D; Haase, W; Sautter-Bihl, M-L; Wenz, F; Schmezer, P; Popanda, O