Porro Antonio相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

USP7 deubiquitinase stabilizes FAN1 to support DNA crosslink repair and suppress CAG repeat expansion

USP7 去泛素化酶稳定 FAN1，从而支持 DNA 交联修复并抑制 CAG 重复序列扩增

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-026-70051-9

Collotta, Giulio; Gatti, Marco; Ungureanu, Irina-Maria; van Ackeren, Vanessa; Rannou, Emilie; Vivalda, Francesca; Gomez Vieito, Diego; Fishwick, Keri M; von Aesch, Christine; Porro, Antonio; Ungerleider, Kyra; Heidari, Ailin; Guérois, Raphaël; Harding, Rachel J; Bischof, Sylvain; Balmus, Gabriel; Sartori, Alessandro A

发表日期：2026

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The PIN1-p38-CtIP signalling axis protects stalled replication forks from deleterious degradation

PIN1-p38-CtIP信号通路保护停滞的复制叉免受有害降解。

期刊:Nucleic Acids Research

影响因子:13.1

doi:10.1093/nar/gkaf278

Vivalda, Francesca; Gatti, Marco; Manfredi, Letizia; Dogan, Hülya; Porro, Antonio; Collotta, Giulio; Ceppi, Ilaria; von Aesch, Christine; van Ackeren, Vanessa; Wild, Sebastian; Steger, Martin; Canovas, Begoña; Cubillos-Rojas, Monica; Riera, Antoni; Cejka, Petr; Nebreda, Angel R; Dibitetto, Diego; Rottenberg, Sven; Sartori, Alessandro A

发表日期：2025

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Disruption of protein-protein interaction hotspots in the C-terminal domain of MLH1 confers mismatch repair deficiency

MLH1 C端结构域中蛋白质-蛋白质相互作用热点的破坏会导致错配修复缺陷。

期刊:NAR Cancer

影响因子:3.2

doi:10.1093/narcan/zcaf055

Fishwick, Keri M; Gomez Vieito, Diego; Greco, Giada; Collotta, Giulio; Gatti, Marco; Kulik, Anastasija A; Guérois, Raphaël; Corbeski, Ivan; Phadte, Ashutosh S; Senoussi, Issam; Cejka, Petr; Pluciennik, Anna; Porro, Antonio; Sartori, Alessandro A

发表日期：2025

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RNAi Screening Uncovers a Synthetic Sick Interaction between CtIP and the BARD1 Tumor Suppressor

RNAi筛选揭示CtIP与BARD1肿瘤抑制因子之间的合成致病相互作用

影响因子:5.2

doi:10.3390/cells11040643

Bolck, Hella A; Przetocka, Sara; Meier, Roger; von Aesch, Christine; Zurfluh, Christina; Hänggi, Kay; Spegg, Vincent; Altmeyer, Matthias; Stebler, Michael; Nørrelykke, Simon F; Horvath, Peter; Sartori, Alessandro A; Porro, Antonio

发表日期：2022

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FAN1, a DNA Repair Nuclease, as a Modifier of Repeat Expansion Disorders

FAN1，一种DNA修复核酸酶，作为重复序列扩增疾病的修饰因子

期刊:Journal of Huntingtons Disease

影响因子:3.1

doi:10.3233/JHD-200448

Deshmukh, Amit L; Porro, Antonio; Mohiuddin, Mohiuddin; Lanni, Stella; Panigrahi, Gagan B; Caron, Marie-Christine; Masson, Jean-Yves; Sartori, Alessandro A; Pearson, Christopher E

发表日期：2021

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A Single-Stranded DNA-Encoded Chemical Library Based on a Stereoisomeric Scaffold Enables Ligand Discovery by Modular Assembly of Building Blocks

基于立体异构骨架的单链DNA编码化学库可通过模块化组装构建模块实现配体发现

期刊:Advanced Science

影响因子:14.1

doi:10.1002/advs.202001970

Bassi, Gabriele; Favalli, Nicholas; Vuk, Miriam; Catalano, Marco; Martinelli, Adriano; Trenner, Anika; Porro, Antonio; Yang, Su; Tham, Chuin Lean; Moroglu, Mustafa; Yue, Wyatt W; Conway, Stuart J; Vogt, Peter K; Sartori, Alessandro A; Scheuermann, Jörg; Neri, Dario

发表日期：2020

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Author Correction: FAN1 interaction with ubiquitylated PCNA alleviates replication stress and preserves genomic integrity independently of BRCA2

作者更正：FAN1 与泛素化 PCNA 的相互作用可缓解复制压力并维持基因组完整性，且该作用独立于 BRCA2。

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-017-02130-x

Porro, Antonio; Berti, Matteo; Pizzolato, Julia; Bologna, Serena; Kaden, Svenja; Saxer, Anja; Ma, Yue; Nagasawa, Kazuo; Sartori, Alessandro A; Jiricny, Josef

发表日期：2017

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Editorial: Grappling with the Multifaceted World of the DNA Damage Response

社论：应对DNA损伤反应的多面性

期刊:Frontiers in Genetics

影响因子:2.8

doi:10.3389/fgene.2016.00091

发表日期：2016

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ABCC multidrug transporters in childhood neuroblastoma: clinical and biological effects independent of cytotoxic drug efflux.

儿童神经母细胞瘤中的 ABCC 多药转运体：与细胞毒性药物外排无关的临床和生物学效应

期刊:Jnci-Journal of the National Cancer Institute

影响因子:7.2

doi:10.1093/jnci/djr256

Henderson Michelle J, Haber Michelle, Porro Antonio, Munoz Marcia A, Iraci Nunzio, Xue Chengyuan, Murray Jayne, Flemming Claudia L, Smith Janice, Fletcher Jamie I, Gherardi Samuele, Kwek Chin-Kiat, Russell Amanda J, Valli Emanuele, London Wendy B, Buxton Allen B, Ashton Lesley J, Sartorelli Alan C, Cohn Susan L, Schwab Manfred, Marshall Glenn M, Perini Giovanni, Norris Murray D

细胞生物学

发表日期：2011

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Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis

通过抑制组蛋白去乙酰化酶激活组织转谷氨酰胺酶转录，作为治疗Myc致癌作用的一种策略

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.0705524104

Liu, Tao; Tee, Andrew E L; Porro, Antonio; Smith, Stewart A; Dwarte, Tanya; Liu, Pei Yan; Iraci, Nunzio; Sekyere, Eric; Haber, Michelle; Norris, Murray D; Diolaiti, Daniel; Della Valle, Giuliano; Perini, Giovanni; Marshall, Glenn M

发表日期：2007

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