日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Proteomic profiling of brain organoids and extracellular vesicles identifies early Alzheimer's disease biomarkers and drug response heterogeneity

脑类器官和细胞外囊泡的蛋白质组学分析可识别早期阿尔茨海默病生物标志物和药物反应异质性

期刊:Alzheimers & Dementia
影响因子:11.1
doi:10.1002/alz.71273
Boyd, Rachel J; Dong, Daiyun; Sagar, Ram; Iliuk, Anton; Ahmed, Waqar; Androni, Xenia; Porsteinsson, Anton P; Rosenberg, Paul B; Lyketsos, Constantine G; Witwer, Kenneth W; Mahairaki, Vasiliki
阿尔茨海默症
神经科学
3D/类器官
囊泡
细胞生物学
发表日期：2026
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Phase 3 randomized clinical trials of simufilam in mild-to-moderate Alzheimer's disease

西莫菲拉姆治疗轻度至中度阿尔茨海默病的3期随机临床试验

期刊:Jpad-Journal of Prevention of Alzheimers Disease
影响因子:7.8
doi:10.1016/j.tjpad.2025.100469
Kupiec, James W; Porsteinsson, Anton P; Turner, Raymond S; Hendrix, Suzanne; Mallinckrodt, Craig; Khan, Arifulla; Cohen, Ian; Liss, Jonathan; Clarnette, Roger; Park, Kee Hyung; Hernandez, Antonio M; Burns, Lindsay H
阿尔茨海默症
发表日期：2026
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Hippocampal Atrophy on Magnetic Resonance Imaging as a Surrogate Marker for Clinical Benefit and Neurodegeneration in Early Symptomatic Alzheimer's Disease: Synthesis of Evidence from Observational and Interventional Trials

磁共振成像中海马萎缩作为早期症状性阿尔茨海默病临床获益和神经退行性变的替代标志物：观察性和干预性试验证据的综合分析

期刊:CNS Drugs
影响因子:7.4
doi:10.1007/s40263-025-01251-y
Abushakra, Susan; Doraiswamy, P Murali; Hey, John A; Tosun, Duygu; Barkhof, Frederik; Barakos, Jerome; Petrella, Jeffrey; Kesslak, J Patrick; Power, Aidan; Sabbagh, Marwan; Porsteinsson, Anton; Cohen, Sharon; Gauthier, Serge; Ritchie, Craig; Watson, David; McSweeney, Emer; Boada, Merce; Liang, Earvin; Bracoud, Luc; McLaine, Rosalind; Flint, Susan; Schaefer, Jean F; Yu, Jeremy; Bray, Margaret; Hendrix, Suzanne; Dickson, Sam; Durrant, Abe; Albayrak, Adem; Tolar, Martin
阿尔茨海默症
Hippo
神经科学
发表日期：2026
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Blood biomarkers for Alzheimer's disease are correlated with measures of agitation and cognition in a randomized trial assessing the effects of escitalopram on agitation

在一项评估艾司西酞普兰对躁动影响的随机试验中，阿尔茨海默病的血液生物标志物与躁动和认知指标相关。

期刊:Alzheimer's and Dementia: Translational Research and Clinical Interventions
影响因子:6.8
doi:10.1002/trc2.70203
Barnwal, Maansi; Baksh, Sheriza; Ismail, Zahinoor; Shade, David M; Moghekar, Abhay; Ho, Sara G; Rosenberg, Paul B; Porsteinsson, Anton P; Lyketsos, Constantine G
阿尔茨海默症
神经科学
发表日期：2026
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Peripheral biomarkers associated with apathy and predicting response to methylphenidate: Secondary analysis of the Apathy in Dementia Methylphenidate Trial 2 (ADMET2) study

与冷漠相关的外周生物标志物及对哌甲酯疗效的预测：痴呆症冷漠哌甲酯试验2 (ADMET2) 研究的二次分析

期刊:International Psychogeriatrics
影响因子:4.3
doi:10.1016/j.inpsyc.2025.100181
Sankhe, Krushnaa; Ruthirakuhan, Myuri; Andreazza, Ana C; Brawman-Mintzer, Olga; Craft, Suzanne; Herrmann, Nathan; Ismail, Zahinoor; Lerner, Alan J; Levey, Allan I; Mintzer, Jacobo; Padala, Prasad R; Perin, Jamie; Porsteinsson, Anton P; Rosenberg, Paul B; Shade, David; Tumati, Shankar; van Dyck, Christopher H; Lanctôt, Krista L
MET
发表日期：2026
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Smartwatch- and smartphone-based remote assessment of brain health and detection of mild cognitive impairment

基于智能手表和智能手机的远程脑健康评估和轻度认知障碍检测

期刊:Nature Medicine
影响因子:50
doi:10.1038/s41591-024-03475-9
Butler, Paul Monroe; Yang, Jenny; Brown, Roland; Hobbs, Matt; Becker, Andrew; Penalver-Andres, Joaquin; Syz, Philippe; Muller, Sofia; Cosne, Gautier; Juraver, Adrien; Song, Han Hee; Saha-Chaudhuri, Paramita; Roggen, Daniel; Scotland, Alf; Silveira, Natalia; Demircioglu, Gizem; Gabelle, Audrey; Hughes, Richard; Erkkinen, Michael G; Langbaum, Jessica B; Lingler, Jennifer H; Price, Pamela; Quiroz, Yakeel T; Sha, Sharon J; Sliwinski, Marty; Porsteinsson, Anton P; Au, Rhoda; Bianchi, Matt T; Lenyoun, Hanson; Pham, Hung; Patel, Mithun; Belachew, Shibeshih
神经科学
发表日期：2025
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Escitalopram for agitation in Alzheimer's dementia: a randomized controlled phase 3 trial

艾司西酞普兰治疗阿尔茨海默病痴呆症躁动：一项随机对照3期试验

期刊:Nature Medicine
影响因子:50
doi:10.1038/s41591-025-03569-y
Rajji, Tarek K; Baksh, Sheriza N; Shade, David M; Ismail, Zahinoor; Burhan, Amer M; Okhravi, Hamid R; Padala, Prasad R; Rosenberg, Paul B; Schneider, Lon S; Porsteinsson, Anton P; Lyketsos, Constantine G
阿尔茨海默症
发表日期：2025
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Clinical Efficacy, Safety and Imaging Effects of Oral Valiltramiprosate in APOEε4/ε4 Homozygotes with Early Alzheimer's Disease: Results of the Phase III, Randomized, Double-Blind, Placebo-Controlled, 78-Week APOLLOE4 Trial

口服缬氨曲普罗酯治疗APOEε4/ε4纯合子早期阿尔茨海默病患者的临床疗效、安全性和影像学效应：III期随机、双盲、安慰剂对照、78周APOLLOE4试验结果

期刊:Drugs
影响因子:14.4
doi:10.1007/s40265-025-02250-5
Abushakra, Susan; Power, Aidan; Watson, David; Porsteinsson, Anton; Sabbagh, Marwan; MacSweeney, Emer; Cohen, Sharon; Boada Rovira, Mercè; Doraiswamy, P Murali; Liang, Earvin; Flint, Susan; Kesslak, J Patrick; McLaine, Rosalind; Albayrak, Adem; Schaefer, Jean; Yu, Jeremy; Tolar, Luke; Dickson, Sam; Hey, John A; Tolar, Martin
阿尔茨海默症
APOE
发表日期：2025
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Sleep variables in the S‐CitAD RCT of escitalopram for agitation in Alzheimer's disease

S-CitAD RCT 中艾司西酞普兰治疗阿尔茨海默病躁动的睡眠变量

期刊:Brain
影响因子:11.7
doi:10.1093/brain/awz113
Lysen, Thom S; Darweesh, Sirwan K L; Ikram, M Kamran; Luik, Annemarie I; Ikram, M Arfan; Rosenberg, Paul B; Manning, Carol A; Porsteinsson, Anton P; Lyketsos, Kostas G; Baksh, Sheriza; Spira, Adam P; Wanigatunga, Sarah K; Burhan, Amer M
阿尔茨海默症
发表日期：2025
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Evaluation of cognitive, functional, and behavioral effects observed in EMERGE, a phase 3 trial of aducanumab in people with early Alzheimer's disease

对 EMERGE 研究中观察到的认知、功能和行为效应进行评估，EMERGE 是一项针对早期阿尔茨海默病患者的 aducanumab 三期临床试验。

期刊:Alzheimers & Dementia
影响因子:11.1
doi:10.1002/alz.70224
Cummings, Jeffrey; Cohen, Sharon; Murphy, Jennifer; Brothers, Holly M; Nejati, Mina; Forrestal, Fiona; de Moor, Carl; O'Gorman, John; Harrison, John; Jaeger, Judith; Mummery, Catherine Jane; Porsteinsson, Anton P; Potashman, Michele; Tian, Ying; Yang, Lili; He, Ping; Haeberlein, Samantha Budd
ERG
阿尔茨海默症
神经科学
发表日期：2025
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