IRS1 is highly expressed in localized breast tumors and regulates the sensitivity of breast cancer cells to chemotherapy, while IRS2 is highly expressed in invasive breast tumors.
IRS1 在局限性乳腺肿瘤中高表达,并调节乳腺癌细胞对化疗的敏感性,而 IRS2 在浸润性乳腺肿瘤中高表达
期刊:Cancer Letters
影响因子:10.1
doi:10.1016/j.canlet.2013.03.030
Porter Holly A, Perry Anthony, Kingsley Chris, Tran Nhan L, Keegan Achsah D