日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Anticodon-edited transfer RNAs (ACE-tRNAs) encoded as therapeutic nonviral minimal DNA vectors

反密码子编辑的转移RNA(ACE-tRNA)编码为治疗性非病毒最小DNA载体

Porter, Joseph J; Ko, Wooree; Sorensen, Emily G; Cheung, Zachary; Thrasher, Kari; Couch, Tyler; Gabell, Jeffrey T; Shwe, Victoria; Hyatt, Julia; Licata, Jennasea B; Peterson, Luke K; Dean, David A; Lueck, John D

G(z)ESTY as an optimized cell-based assay for initial steps in GPCR deorphanization.

G(z)ESTY 是一种优化的基于细胞的检测方法,用于 GPCR 去孤儿化的初始步骤

Franchini Luca, Porter Joseph J, Lueck John D, Orlandi Cesare

ACE-tRNAs are a platform technology for suppressing nonsense mutations that cause cystic fibrosis.

ACE-tRNA 是一种用于抑制导致囊性纤维化的无义突变的平台技术

Ko Wooree, Porter Joseph J, Spelier Sacha, Sorensen Emily G, Bhatt Priyanka, Gabell Jeffrey T, van der Windt Isabelle, Couch Tyler, Coote Kevin, Mense Martin, Beekman Jeffrey M, Lueck John D

Subnuclear organization and mislocalization of plasmids reduce transgene expression

质粒的亚核组织结构异常和定位错误会降低转基因表达

Gu, Ningyang; Baliga, Uday K; Porter, Joseph J; Lueck, John D; Dean, David A

Optimization of ACE-tRNAs function in translation for suppression of nonsense mutations

优化ACE-tRNA在翻译中的功能以抑制无义突变

Porter, Joseph J; Ko, Wooree; Sorensen, Emily G; Lueck, John D

A cystic fibrosis gene editing approach that is on target

一种靶向囊性纤维化的基因编辑方法

Porter, Joseph J; Lueck, John D

Engineered tRNAs efficiently suppress CDKL5 premature termination codons

工程改造的tRNA能有效抑制CDKL5提前终止密码子

Pezzini, Stefano; Mustaccia, Aurora; Aboa, Pierre; Faustini, Giorgia; Branchini, Alessio; Pinotti, Mirko; Frasca, Angelisa; Porter, Joseph J; Lueck, John D; Landsberger, Nicoletta

Therapeutic promise of engineered nonsense suppressor tRNAs

工程化无义抑制tRNA的治疗前景

Porter, Joseph J; Heil, Christina S; Lueck, John D

Dissecting Optical Response and Molecular Structure of Fluorescent Proteins With Non-canonical Chromophores

解析具有非典型发色团的荧光蛋白的光学响应和分子结构

Oscar, Breland G; Zhu, Liangdong; Wolfendeen, Hayati; Rozanov, Nikita D; Chang, Alvin; Stout, Kenneth T; Sandwisch, Jason W; Porter, Joseph J; Mehl, Ryan A; Fang, Chong

Structural insights into a thermostable variant of human carbonic anhydrase II

人类碳酸酐酶II热稳定变体的结构解析

Kean, Kelsey M; Porter, Joseph J; Mehl, Ryan A; Karplus, P Andrew