日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Endogenous retroelements in hematological malignancies: From epigenetic dysregulation to therapeutic targeting

血液系统恶性肿瘤中的内源性逆转录元件:从表观遗传失调到治疗靶向

Chour, Mohamed; Porteu, Françoise; Depil, Stéphane; Alcazer, Vincent

Revisiting Clonal Evolution Through the Light of Retrotransposons

从逆转录转座子的角度重新审视克隆进化

Lamoureux, Anaïs; Elvira-Matelot, Emilie; Porteu, Françoise; Laplane, Lucie

CXCL8 secreted by immature granulocytes inhibits WT hematopoiesis in chronic myelomonocytic leukemia

未成熟粒细胞分泌的CXCL8抑制慢性粒单核细胞白血病中的野生型造血作用

Deschamps, Paul; Wacheux, Margaux; Gosseye, Axel; Morabito, Margot; Pagès, Arnaud; Lyne, Anne-Marie; Alfaro, Alexia; Rameau, Philippe; Imanci, Aygun; Chelbi, Rabie; Marchand, Valentine; Renneville, Aline; Patnaik, Mrinal M; Lapierre, Valerie; Badaoui, Bouchra; Wagner-Ballon, Orianne; Berthon, Céline; Braun, Thorsten; Willekens, Christophe; Itzykson, Raphael; Fenaux, Pierre; Thépot, Sylvain; Etienne, Gabriel; Elvira-Matelot, Emilie; Porteu, Francoise; Droin, Nathalie; Perié, Leïla; Laplane, Lucie; Solary, Eric; Selimoglu-Buet, Dorothée

The localization, origin, and impact of platelets in the tumor microenvironment are tumor type-dependent

血小板在肿瘤微环境中的定位、来源和作用取决于肿瘤类型。

Le Chapelain, Ophélie; Jadoui, Soumaya; Gros, Angèle; Barbaria, Samir; Benmeziane, Keltouma; Ollivier, Véronique; Dupont, Sébastien; Solo Nomenjanahary, Mialitiana; Mavouna, Sabrina; Rogozarski, Jasmina; Mawhin, Marie-Anne; Caligiuri, Giuseppina; Delbosc, Sandrine; Porteu, Françoise; Nieswandt, Bernhard; Mangin, Pierre H; Boulaftali, Yacine; Ho-Tin-Noé, Benoit

Monocytes generated by interleukin-6-treated human hematopoietic stem and progenitor cells secrete calprotectin that inhibits erythropoiesis

由白细胞介素-6处理的人类造血干细胞和祖细胞生成的单核细胞分泌钙卫蛋白,从而抑制红细胞生成。

Valentine Marchand ,Lucie Laplane ,Louis Valensi ,Isabelle Plo ,Marine Aglave ,Aymeric Silvin ,Florence Pasquier ,Françoise Porteu ,William Vainchenker ,Dorothée Selimoglu-Buet ,Nathalie Droin ,Hana Raslova ,Virginie Marcel ,Jean-Jacques Diaz ,Michaela Fontenay ,Eric Solary

NF-κB signaling controls H3K9me3 levels at intronic LINE-1 and hematopoietic stem cell genes in cis

NF-κB 信号控制内含子 LINE-1 和顺式造血干细胞基因的 H3K9me3 水平

Yanis Pelinski, Donia Hidaoui #, Anne Stolz #, François Hermetet, Rabie Chelbi, M'boyba Khadija Diop, Amir M Chioukh, Françoise Porteu #, Emilie Elvira-Matelot #

Macrophage migration inhibitory factor is overproduced through EGR1 in TET2low resting monocytes

巨噬细胞移动抑制因子在 TET2low 静息单核细胞中通过 EGR1 过量产生

Elodie Pronier #, Aygun Imanci #, Dorothée Selimoglu-Buet, Bouchra Badaoui, Raphael Itzykson, Thierry Roger, Chloé Jego, Audrey Naimo, Maëla Francillette, Marie Breckler, Orianne Wagner-Ballon, Maria E Figueroa, Marine Aglave, Daniel Gautheret, Françoise Porteu, Olivier A Bernard, William Vainchenke

Gene correction for SCID-X1 in long-term hematopoietic stem cells

长期造血干细胞中 SCID-X1 的基因校正

Mara Pavel-Dinu, Volker Wiebking, Beruh T Dejene, Waracharee Srifa, Sruthi Mantri, Carmencita E Nicolas, Ciaran Lee, Gang Bao, Eric J Kildebeck, Niraj Punjya, Camille Sindhu, Matthew A Inlay, Nivedita Saxena, Suk See DeRavin, Harry Malech, Maria Grazia Roncarolo, Kenneth I Weinberg, Matthew H Porteu

Age-Associated Decrease of the Histone Methyltransferase SUV39H1 in HSC Perturbs Heterochromatin and B Lymphoid Differentiation

造血干细胞中组蛋白甲基转移酶SUV39H1的年龄相关性下降会扰乱异染色质和B淋巴细胞分化

Djeghloul, Dounia; Kuranda, Klaudia; Kuzniak, Isabelle; Barbieri, Daniela; Naguibneva, Irina; Choisy, Caroline; Bories, Jean-Christophe; Dosquet, Christine; Pla, Marika; Vanneaux, Valérie; Socié, Gérard; Porteu, Françoise; Garrick, David; Goodhardt, Michele

Thrombopoietin promotes NHEJ DNA repair in hematopoietic stem cells through specific activation of Erk and NF-κB pathways and their target, IEX-1

血小板生成素通过特异性激活 Erk 和 NF-κB 通路及其靶标 IEX-1 促进造血干细胞中的 NHEJ DNA 修复

Bérengère de Laval, Patrycja Pawlikowska, Daniela Barbieri, Corinne Besnard-Guerin, Alba Cico, Rajiv Kumar, Murielle Gaudry, Véronique Baud, Françoise Porteu