日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CD40 Induces Unfolded Protein Response, Upregulation of VEGF, and Vascular Leakage in Diabetic Retinopathy

CD40诱导糖尿病视网膜病变中的未折叠蛋白反应、VEGF上调和血管渗漏

Vos, Sarah; Portillo, Jose-Andres C; Hubal, Alyssa; Bapputty, Reena; Pfaff, Amelia; Aaron, Rachel; Weng, Matthew; Sun, Da; Lu, Zheng-Rong; Yu, Jin-Sang; Subauste, Carlos S

Disruption of retinal inflammation and the development of diabetic retinopathy in mice by a CD40-derived peptide or mutation of CD40 in Müller cells

CD40衍生肽或Müller细胞中CD40突变可干扰小鼠视网膜炎症并导致糖尿病视网膜病变的发生

Portillo, Jose-Andres C; Yu, Jin-Sang; Vos, Sarah; Bapputty, Reena; Lopez Corcino, Yalitza; Hubal, Alyssa; Daw, Jad; Arora, Sahil; Sun, Wenyu; Lu, Zheng-Rong; Subauste, Carlos S

CD40 Expressed in Endothelial Cells Promotes Upregulation of ICAM-1 But Not Pro-Inflammatory Cytokines, NOS2 and P2X7 in the Diabetic Retina.

内皮细胞中表达的 CD40 可促进糖尿病视网膜中 ICAM-1 的上调,但不会影响促炎细胞因子、NOS2 和 P2X7 的上调

Yu Jin-Sang, Daw Jad, Portillo Jose-Andres C, Subauste Carlos S

CD40 in Endothelial Cells Restricts Neural Tissue Invasion by Toxoplasma gondii.

内皮细胞中的CD40限制弓形虫对神经组织的侵袭

Portillo Jose-Andres C, Van Grol Jennifer, Saffo Saad, Lopez Corcino Yalitza, Rodriguez Myriam, Fox Barbara A, Bzik David J, Ward Nicole L, Dubyak George R, Rojas Roxana E, Toosi Zahra, Subauste Carlos S

Loss of CD40 attenuates experimental diabetes-induced retinal inflammation but does not protect mice from electroretinogram defects

CD40 的缺失可减轻实验性糖尿病引起的视网膜炎症,但不能保护小鼠免受视网膜电图缺陷的影响。

Samuels, Ivy S; Portillo, Jose-Andres C; Miao, Yanling; Kern, Timothy S; Subauste, Carlos S

Identification of Signaling Pathways by Which CD40 Stimulates Autophagy and Antimicrobial Activity against Toxoplasma gondii in Macrophages

鉴定CD40刺激巨噬细胞自噬和抗弓形虫抗菌活性的信号通路

Liu, Elizabeth; Lopez Corcino, Yalitza; Portillo, Jose-Andres C; Miao, Yanling; Subauste, Carlos S

Blockade of CD40-TRAF2,3 or CD40-TRAF6 is sufficient to inhibit pro-inflammatory responses in non-haematopoietic cells

阻断 CD40-TRAF2、3 或 CD40-TRAF6 足以抑制非造血细胞中的促炎反应。

Portillo, Jose-Andres C; Greene, Jennifer A; Schwartz, Isaac; Subauste, Maria Cecilia; Subauste, Carlos S

CD40 promotes the development of early diabetic retinopathy in mice.

CD40促进小鼠早期糖尿病视网膜病变的发生发展

Portillo Jose-Andres C, Greene Jennifer A, Okenka Genevieve, Miao Yanling, Sheibani Nader, Kern Timothy S, Subauste Carlos S

Proinflammatory responses induced by CD40 in retinal endothelial and Müller cells are inhibited by blocking CD40-Traf2,3 or CD40-Traf6 signaling

阻断 CD40-Traf2,3 或 CD40-Traf6 信号通路可抑制视网膜内皮细胞和 Müller 细胞中 CD40 诱导的促炎反应。

Portillo, Jose-Andres C; Schwartz, Isaac; Zarini, Simona; Bapputty, Reena; Kern, Timothy S; Gubitosi-Klug, Rose A; Murphy, Robert C; Subauste, M Cecilia; Subauste, Carlos S

Toxoplasma gondii-induced activation of EGFR prevents autophagy protein-mediated killing of the parasite

弓形虫诱导的 EGFR 激活可阻止自噬蛋白介导的寄生虫杀灭。

Muniz-Feliciano, Luis; Van Grol, Jennifer; Portillo, Jose-Andres C; Liew, Lloyd; Liu, Bing; Carlin, Cathleen R; Carruthers, Vern B; Matthews, Stephen; Subauste, Carlos S