日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Safety and Pharmacokinetics of LHF-535, a Potential Treatment for Lassa Fever, in Healthy Adults

LHF-535(一种潜在的拉沙热治疗药物)在健康成人中的安全性和药代动力学研究

Amberg, Sean M; Snyder, Benjamin; Vliet-Gregg, Portia A; Tarcha, Eric J; Posakony, Jeff; Bedard, Kristin M; Heald, Alison E

Lassa antiviral LHF-535 protects guinea pigs from lethal challenge

拉沙病毒抗病毒药物LHF-535可保护豚鼠免受致命攻击

Cashman, Kathleen A; Wilkinson, Eric R; Posakony, Jeffrey; Madu, Ikenna G; Tarcha, Eric J; Lustig, Kurt H; Korth, Marcus J; Bedard, Kristin M; Amberg, Sean M

Disparate expression specificities coded by a shared Hox-C enhancer

由共享的 Hox-C 增强子编码的不同表达特异性

Steve W Miller, James W Posakony

Evolutionary emergence of Hairless as a novel component of the Notch signaling pathway.

Hairless 的进化出现是 Notch 信号通路的一个新组成部分

Miller Steven W, Movsesyan Artem, Zhang Sui, Fernández Rosa, Posakony James W

Lateral inhibition: Two modes of non-autonomous negative autoregulation by neuralized

侧抑制:神经化非自主负向自身调节的两种模式

Miller, Steven W; Posakony, James W

Targeting Innate Immunity for Antiviral Therapy through Small Molecule Agonists of the RLR Pathway

利用RLR通路小分子激动剂靶向先天免疫进行抗病毒治疗

Pattabhi, Sowmya; Wilkins, Courtney R; Dong, Ran; Knoll, Megan L; Posakony, Jeffrey; Kaiser, Shari; Mire, Chad E; Wang, Myra L; Ireton, Renee C; Geisbert, Thomas W; Bedard, Kristin M; Iadonato, Shawn P; Loo, Yueh-Ming; Gale, Michael Jr

An enhancer composed of interlocking submodules controls transcriptional autoregulation of suppressor of hairless

由相互连接的子模块组成的增强子控制着无毛抑制因子的转录自调控。

Liu, Feng; Posakony, James W

Role of architecture in the function and specificity of two Notch-regulated transcriptional enhancer modules

结构在两个Notch调控的转录增强子模块的功能和特异性中的作用

Liu, Feng; Posakony, James W

Ancestral and conserved cis-regulatory architectures in developmental control genes

发育控制基因中祖先的和保守的顺式调控结构

Rebeiz, Mark; Castro, Brian; Liu, Feng; Yue, Feng; Posakony, James W

A cis-regulatory map of the Drosophila genome

果蝇基因组的顺式调控图谱

Nègre, Nicolas; Brown, Christopher D; Ma, Lijia; Bristow, Christopher Aaron; Miller, Steven W; Wagner, Ulrich; Kheradpour, Pouya; Eaton, Matthew L; Loriaux, Paul; Sealfon, Rachel; Li, Zirong; Ishii, Haruhiko; Spokony, Rebecca F; Chen, Jia; Hwang, Lindsay; Cheng, Chao; Auburn, Richard P; Davis, Melissa B; Domanus, Marc; Shah, Parantu K; Morrison, Carolyn A; Zieba, Jennifer; Suchy, Sarah; Senderowicz, Lionel; Victorsen, Alec; Bild, Nicholas A; Grundstad, A Jason; Hanley, David; MacAlpine, David M; Mannervik, Mattias; Venken, Koen; Bellen, Hugo; White, Robert; Gerstein, Mark; Russell, Steven; Grossman, Robert L; Ren, Bing; Posakony, James W; Kellis, Manolis; White, Kevin P