日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Comprehensive DSRCT multi-omics analyses unveil CACNA2D2 as a diagnostic hallmark and super-enhancer-driven EWSR1::WT1 signature gene

全面的DSRCT多组学分析揭示CACNA2D2是诊断标志物,也是由超级增强子驱动的EWSR1::WT1特征基因。

Geyer, Florian Henning; Ritter, Alina; Kinn-Gurzo, Seneca; Faehling, Tobias; Li, Jing; Jarosch, Armin; Ngo, Carine; Vinca, Endrit; Aljakouch, Karim; Orynbek, Azhar; Ohmura, Shunya; Kirchner, Thomas; Imle, Roland; Romero-Pérez, Laura; Díaz-Martín, Juan; Bertram, Stefanie; de Álava, Enrique; Henon, Clémence; Postel-Vilnay, Sophie; Banito, Ana; Sill, Martin; Versleijen-Jonkers, Yvonne; Mayer, Benjamin Friedrich Berthold; Ebinger, Martin; Sparber-Sauer, Monika; Stegmaier, Sabine; Baumhoer, Daniel; Hartmann, Wolfgang; Krijgsveld, Jeroen; Horst, David; Delattre, Olivier; Grohar, Patrick Joseph; Grünewald, Thomas Georg Phillip; Cidre-Aranaz, Florencia

Multi-omics profiling identified two epithelioid sarcoma molecular subtypes with distinct signaling and immune characteristics

多组学分析鉴定出两种具有不同信号传导和免疫特征的上皮样肉瘤分子亚型。

Ngo, Carine; Colmet-Daage, Léo; Vibert, Julien; Hénon, Clémence; Pissaloux, Daniel; Valent, Alexander; Xiang Jin, Jia; Brillet, Riwan; Masliah-Planchon, Julien; Pierron, Gaëlle; Lacroix, Ludovic; Rouleau, Etienne; Roussel-Simonin, Cyril; Lecorgne, Lilian; Astier, Clémence; Garrido, Marlène; Bahleda, Rastislav; Verret, Benjamin; Cesne, Axel Le; Honore, Charles; Faron, Matthieu; Herman Fridman, Wolf; Sautès-Fridman, Catherine; Coindre, Jean-Michel; Scoazec, Jean-Yves; Waterfall, Joshua J; Bourdeaut, Franck; Grünewald, Thomas G P; Blay, Jean-Yves; Tirode, Franck; Postel-Vinay, Sophie

MAT2A inhibitor AG-270/S095033 in patients with advanced malignancies: a phase I trial

MAT2A抑制剂AG-270/S095033治疗晚期恶性肿瘤患者:一项I期试验

Gounder, Mrinal; Johnson, Melissa; Heist, Rebecca S; Shapiro, Geoffrey I; Postel-Vinay, Sophie; Wilson, Frederick H; Garralda, Elena; Wulf, Gerburg; Almon, Caroline; Nabhan, Salah; Aguado-Fraile, Elia; He, Peng; Romagnoli, Mathilde; Hossain, Mohammad; Narayanaswamy, Rohini; Sadou-Dubourgnoux, Amel; Cooper, Michael; Askoxylakis, Vasileios; Burris, Howard A; Tabernero, Josep

Autocrine interferon poisoning mediates ADAR1-dependent synthetic lethality in BRCA1/2-mutant cancers

自分泌干扰素中毒介导 BRCA1/2 突变癌症中 ADAR1 依赖性合成致死

Roman M Chabanon ,Liudmila Shcherbakova ,Magali Lacroix-Triki ,Marine Aglave ,Jean Zeghondy ,Victor Kriaa ,Antoine Gougé ,Marlène Garrido ,Elodie Edmond ,Ludovic Bigot ,Dragomir B Krastev ,Rachel Brough ,Stephen J Pettitt ,Thibault Thomas-Bonafos ,Robert Samstein ,Christophe Massard ,Marc Deloger ,Andrew Nj Tutt ,Fabrice Barlesi ,Yohann Loriot ,Suzette Delaloge ,Marcel Tawk ,Cindy Degerny ,Yea-Lih Lin ,Barbara Pistilli ,Philippe Pasero ,Christopher J Lord ,Sophie Postel-Vinay

Plasticity of human resilience mechanisms

人类韧性机制的可塑性

Leone, Giovanni; Casanave, Hannah; Postel, Charlotte; Fraisse, Florence; Vallée, Thomas; de La Sayette, Vincent; Dayan, Jacques; Peschanski, Denis; Eustache, Francis; Gagnepain, Pierre

Genome instability and crosstalk with the immune response

基因组不稳定性及其与免疫反应的相互作用

Chabanon, Roman M; Danlos, François-Xavier; Ouali, Kaissa; Postel-Vinay, Sophie

AZD8701, an Antisense Oligonucleotide Targeting FOXP3 mRNA, as Monotherapy and in Combination with Durvalumab: A Phase I Trial in Patients with Advanced Solid Tumors

AZD8701,一种靶向FOXP3 mRNA的反义寡核苷酸,作为单药疗法以及与度伐利尤单抗联合疗法:一项针对晚期实体瘤患者的I期试验

Siu, Lillian L; Postel-Vinay, Sophie; Villanueva-Vázquez, Rafael; de Velasco, Guillermo; Castanon Alvarez, Eduardo; Kyriakopoulos, Christos E; Johnson, Melissa; Ouali, Kaïssa; McMorn, Stephen; Angell, Helen K; Ng, Felicia; Saran, Shashank; Bayat, Mahdiye; Collins, Teresa; Roy, Archana; Lambert, Arthur W; Cho, Song; Miller, Neil; Petruzzelli, Michele; Stone, John; Massard, Christophe

Final results from the phase Ia/Ib study of the novel bromodomain and extra-terminal domain inhibitor, BI 894999, in patients with advanced solid tumors or diffuse large B-cell lymphoma

新型溴结构域和末端结构域抑制剂 BI 894999 治疗晚期实体瘤或弥漫性大B细胞淋巴瘤患者的 Ia/Ib 期研究的最终结果

Lauer, U M; Awada, A; Postel-Vinay, S; Shapiro, G I; Thieblemont, C; Piha-Paul, S A; Paik, P K; Shepard, D R; Docampo, L I; Galot, R; Rottey, S; Sadrolhefazi, B; Marzin, K; Musa, H; Schöffski, P

Genomic studies in Linum shed light on the evolution of the distyly supergene and the molecular basis of convergent floral evolution

亚麻属植物的基因组研究揭示了二型花柱超基因的演化以及趋同花部演化的分子基础。

Zervakis, Panagiotis-Ioannis; Postel, Zoé; Losvik, Aleksandra; Fracassetti, Marco; Solér, Lucile; Proux-Wéra, Estelle; Bunikis, Ignas; Churcher, Allison; Slotte, Tanja

Exploring KAT6 as a therapeutic target in breast cancer: epigenetic approaches for precision medicine

探索KAT6作为乳腺癌治疗靶点的可能性:精准医学的表观遗传学方法

Roussel-Simonin, Cyril; Fernandez-Martinez, Aranzazu; Postel-Vinay, Sophie; Mosele, Fernanda; Viansone, Alessandro; Massard, Christophe; Mouren, Adrien; Vibert, Julien; Pistilli, Barbara