日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural characterization of antibody-responses following Zolgensma treatment for AAV capsid engineering to expand patient cohorts.

对Zolgensma治疗后抗体反应的结构进行表征,以进行AAV衣壳工程改造,从而扩大患者群体

Mietzsch Mario, Hsi Jane, Nelson Austin R, Khandekar Neeta, Huang Ann-Maree, Smith Nicholas Jc, Zachary Jon, Potts Lindsay, Farrar Michelle A, Chipman Paul, Ghanem Mohammad, Alexander Ian E, Logan Grant J, Huiskonen Juha T, McKenna Robert

Structural characterization of antibody-responses from Zolgensma treatment provides the blueprint for the engineering of an AAV capsid suitable for redosing

对Zolgensma治疗后抗体反应的结构表征为设计适用于重复给药的AAV衣壳提供了蓝图。

Mietzsch, Mario; Nelson, Austin R; Hsi, Jane; Zachary, Jon; Potts, Lindsay; Chipman, Paul; Ghanem, Mohammad; Khandekar, Neeta; Alexander, Ian E; Logan, Grant J; Huiskonen, Juha T; McKenna, Robert

Mercaptopurine versus placebo to prevent recurrence of Crohn's disease after surgical resection (TOPPIC): a multicentre, double-blind, randomised controlled trial

巯嘌呤与安慰剂预防克罗恩病手术切除后复发(TOPPIC):一项多中心、双盲、随机对照试验

Mowat, Craig; Arnott, Ian; Cahill, Aiden; Smith, Malcolm; Ahmad, Tariq; Subramanian, Sreedhar; Travis, Simon; Morris, John; Hamlin, John; Dhar, Anjan; Nwokolo, Chuka; Edwards, Cathryn; Creed, Tom; Bloom, Stuart; Yousif, Mohamed; Thomas, Linzi; Campbell, Simon; Lewis, Stephen J; Sebastian, Shaji; Sen, Sandip; Lal, Simon; Hawkey, Chris; Murray, Charles; Cummings, Fraser; Goh, Jason; Lindsay, James O; Arebi, Naila; Potts, Lindsay; McKinley, Aileen J; Thomson, John M; Todd, John A; Collie, Mhairi; Dunlop, Malcolm G; Mowat, Ashley; Gaya, Daniel R; Winter, Jack; Naismith, Graham D; Ennis, Holly; Keerie, Catriona; Lewis, Steff; Prescott, Robin J; Kennedy, Nicholas A; Satsangi, Jack