文献库，生知库 | 链接生命科学的每一步

Shaw, Lauren C; Poussin, Mathilde; Rodriguez-Garcia, Alba; Eggold, Joshua; Minutolo, Nicholas G; Wang, Jie; Rook, Alain H; Schuster, Stephen J; Powell, Daniel J

T细胞

细胞生物学

免疫/内分泌

发表日期：2023

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Effective adoptive immunotherapy of triple-negative breast cancer by folate receptor-alpha redirected CAR T cells is influenced by surface antigen expression level.

叶酸受体α重定向CAR T细胞对三阴性乳腺癌的有效过继免疫疗法受表面抗原表达水平的影响

期刊:Journal of Hematology & Oncology

影响因子:40.4

doi:10.1186/s13045-016-0285-y

Song De-Gang, Ye Qunrui, Poussin Mathilde, Chacon Jessica A, Figini Mariangela, Powell Daniel J Jr

Multiparameter comparative analysis reveals differential impacts of various cytokines on CART cell phenotype and function ex vivo and in vivo

多参数比较分析揭示了不同细胞因子对体外和体内CAR-T细胞表型和功能的不同影响

期刊:Oncotarget

影响因子:

doi:10.18632/oncotarget.10510

Xu, Xiao-Jun; Song, De-Gang; Poussin, Mathilde; Ye, Qunrui; Sharma, Prannda; Rodríguez-García, Alba; Tang, Yong-Min; Powell, Daniel J

A fully human chimeric antigen receptor with potent activity against cancer cells but reduced risk for off-tumor toxicity

一种完全人源化的嵌合抗原受体，对癌细胞具有强大的活性，但对肿瘤外毒性的风险较低。

期刊:Oncotarget

影响因子:

doi:10.18632/oncotarget.4071

Song, De-Gang; Ye, Qunrui; Poussin, Mathilde; Liu, Lin; Figini, Mariangela; Powell, Daniel J Jr

Rigorous optimization and validation of potent RNA CAR T cell therapy for the treatment of common epithelial cancers expressing folate receptor

对用于治疗表达叶酸受体的常见上皮癌的高效RNA CAR T细胞疗法进行严格优化和验证

期刊:Oncotarget

影响因子:

doi:10.18632/oncotarget.5029

Schutsky, Keith; Song, D Gang; Lynn, Rachel; Smith, Jenessa B; Poussin, Mathilde; Figini, Mariangela; Zhao, Yangbing; Powell, Daniel J Jr

CD137 accurately identifies and enriches for naturally occurring tumor-reactive T cells in tumor

CD137能够准确识别并富集肿瘤中天然存在的肿瘤反应性T细胞。

期刊:Clinical Cancer Research

影响因子:10.2

doi:10.1158/1078-0432.CCR-13-0945

Ye, Qunrui; Song, De-Gang; Poussin, Mathilde; Yamamoto, Tori; Best, Andrew; Li, Chunsheng; Coukos, George; Powell, Daniel J Jr

A human ErbB2-specific T-cell receptor confers potent antitumor effector functions in genetically engineered primary cytotoxic lymphocytes

人类ErbB2特异性T细胞受体赋予基因工程改造的原代细胞毒性淋巴细胞强大的抗肿瘤效应功能

期刊:Human Gene Therapy

影响因子:4

doi:10.1089/hum.2014.006

Lanitis, Evripidis; Smith, Jenessa B; Dangaj, Denarda; Flingai, Seleeke; Poussin, Mathilde; Xu, Shuwen; Czerniecki, Brian J; Li, Yong F; Robbins, Paul F; Powell, Daniel J Jr

Chimeric antigen receptor T Cells with dissociated signaling domains exhibit focused antitumor activity with reduced potential for toxicity in vivo

具有分离信号域的嵌合抗原受体T细胞表现出靶向抗肿瘤活性，且体内毒性降低。

期刊:Cancer Immunology Research

影响因子:8.2

doi:10.1158/2326-6066.CIR-13-0008

Lanitis, Evripidis; Poussin, Mathilde; Klattenhoff, Alex W; Song, Degang; Sandaltzopoulos, Raphael; June, Carl H; Powell, Daniel J Jr

A universal strategy for adoptive immunotherapy of cancer through use of a novel T-cell antigen receptor

利用新型T细胞抗原受体进行癌症过继免疫治疗的通用策略

期刊:Cancer Research

影响因子:16.6

doi:10.1158/0008-5472.CAN-11-3890

Urbanska, Katarzyna; Lanitis, Evripidis; Poussin, Mathilde; Lynn, Rachel C; Gavin, Brian P; Kelderman, Sander; Yu, Jason; Scholler, Nathalie; Powell, Daniel J Jr

Evidence for the involvement of ActA in maturation of the Listeria monocytogenes phagosome

证据表明 ActA 参与单核细胞增生李斯特菌吞噬体的成熟过程

期刊:Cell Research

影响因子:25.9

doi:10.1038/cr.2009.142

Poussin, Mathilde A; Goldfine, Howard

TCRvβ-CART therapy mediates high-precision targeting of malignant T-cell clones

TCRvβ-CART疗法可高精度靶向恶性T细胞克隆

Effective adoptive immunotherapy of triple-negative breast cancer by folate receptor-alpha redirected CAR T cells is influenced by surface antigen expression level.

叶酸受体α重定向CAR T细胞对三阴性乳腺癌的有效过继免疫疗法受表面抗原表达水平的影响

Multiparameter comparative analysis reveals differential impacts of various cytokines on CART cell phenotype and function ex vivo and in vivo

多参数比较分析揭示了不同细胞因子对体外和体内CAR-T细胞表型和功能的不同影响

A fully human chimeric antigen receptor with potent activity against cancer cells but reduced risk for off-tumor toxicity

一种完全人源化的嵌合抗原受体，对癌细胞具有强大的活性，但对肿瘤外毒性的风险较低。

Rigorous optimization and validation of potent RNA CAR T cell therapy for the treatment of common epithelial cancers expressing folate receptor

对用于治疗表达叶酸受体的常见上皮癌的高效RNA CAR T细胞疗法进行严格优化和验证

CD137 accurately identifies and enriches for naturally occurring tumor-reactive T cells in tumor

CD137能够准确识别并富集肿瘤中天然存在的肿瘤反应性T细胞。

A human ErbB2-specific T-cell receptor confers potent antitumor effector functions in genetically engineered primary cytotoxic lymphocytes

人类ErbB2特异性T细胞受体赋予基因工程改造的原代细胞毒性淋巴细胞强大的抗肿瘤效应功能

Chimeric antigen receptor T Cells with dissociated signaling domains exhibit focused antitumor activity with reduced potential for toxicity in vivo

具有分离信号域的嵌合抗原受体T细胞表现出靶向抗肿瘤活性，且体内毒性降低。

A universal strategy for adoptive immunotherapy of cancer through use of a novel T-cell antigen receptor

利用新型T细胞抗原受体进行癌症过继免疫治疗的通用策略

Evidence for the involvement of ActA in maturation of the Listeria monocytogenes phagosome

证据表明 ActA 参与单核细胞增生李斯特菌吞噬体的成熟过程