日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Age-related differences in mRNA vaccine immunogenicity and adjuvancy

mRNA疫苗免疫原性和佐剂的年龄相关差异

Chinni, Shivali Savita; Trollope, Gemma S; Leung, Patrick; McQualter, Jonathan L; Tan, Chee Wah; Wang, Linfa; Lim, Leonard; Wheatley, Adam K; Juno, Jennifer A; Kent, Stephen J; Al-Wassiti, Hareth A; Pouton, Colin W; Quinn, Kylie M

A versatile antibody capture system drives specific in vivo delivery of mRNA-loaded lipid nanoparticles

一种多功能抗体捕获系统可驱动载有mRNA的脂质纳米颗粒在体内进行特异性递送。

Chen, Moore Z; Yuen, Daniel; McLeod, Victoria M; Yong, Ken W; Smyth, Cameron H; Herling, Bruna Rossi; Payne, Thomas J; Fabb, Stewart A; Belousoff, Matthew J; Algarni, Azizah; Sexton, Patrick M; Porter, Christopher J H; Pouton, Colin W; Johnston, Angus P R

Efficient mRNA delivery to resting T cells to reverse HIV latency.

将mRNA高效递送至静息T细胞以逆转HIV潜伏期

Cevaal Paula M, Kan Stanislav, Fisher Bridget M, Moso Michael A, Tan Abigail, Liu Haiyin, Ali Abdalla, Tanaka Kiho, Shepherd Rory A, Kim Youry, Ong Jesslyn, Furtado Denzil L, Holz Marvin, Purcell Damian F J, Casan Joshua M L, Payne Thomas, Zhao Wei, Fareh Mohamed, McMahon James H, Deeks Steven G, Hoh Rebecca, Telwatte Sushama, Pouton Colin W, Johnston Angus P R, Caruso Frank, Symons Jori, Lewin Sharon R, Roche Michael

Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection

短暂抑制I型干扰素可增强CD8+ T细胞干性及疫苗保护作用

Broomfield, Benjamin J; Tan, Chin Wee; Qin, Raymond Z; Abberger, Hanna; Duckworth, Brigette C; Alvarado, Carolina; Dalit, Lennard; Lee, Chee Leng; Shandre Mugan, Rekha; Mazrad, Zihnil A I; Muramatsu, Hiromi; Mackiewicz, Liana; Williams, Bailey E; Chen, Jinjin; Takanashi, Asuka; Fabb, Stewart; Pellegrini, Marc; Rogers, Kelly L; Moon, Woohyun J; Pouton, Colin W; Davis, Melissa J; Nutt, Stephen L; Pardi, Norbert; Wimmer, Verena C; Groom, Joanna R

Morphological changes induced by buffer exchange during preparation of mRNA-lipid nanoparticles occur in a stepwise manner as pH is elevated

在制备mRNA-脂质纳米颗粒的过程中,缓冲液交换引起的形态变化随着pH值的升高而逐步发生。

He, Yujia; Pilkington, Emily H; Kang, Hee Jung; Fong, Wye-Khay; Clulow, Andrew J; Johnston, Angus P R; Pouton, Colin W

Structuring of lipid nanoparticle mRNA formulations at acidic and neutral pH: X-ray scattering and molecular dynamics studies

酸性和中性pH条件下脂质纳米颗粒mRNA制剂的结构:X射线散射和分子动力学研究

Guruge, Amali G; He, Yujia; Clulow, Andrew J; Pouton, Colin W; Chalmers, David K

mRNA vaccines encoding membrane-anchored RBDs of SARS-CoV-2 mutants induce strong humoral responses and can overcome immune imprinting

编码SARS-CoV-2突变体膜锚定RBD的mRNA疫苗可诱导强烈的体液免疫反应,并能克服免疫印迹。

Al-Wassiti, Hareth A; Fabb, Stewart A; Grimley, Samantha L; Kochappan, Ruby; Ho, Joan K; Wong, Chinn Yi; Tan, Chee Wah; Payne, Thomas J; Takanashi, Asuka; Lee, Chee Leng; Mugan, Rekha Shandre; Sicilia, Horatio; Teo, Serena L Y; McAuley, Julie; Ellenberg, Paula; Cooney, James P; Davidson, Kathryn C; Bowen, Richard; Pellegrini, Marc; Rockman, Steven; Godfrey, Dale I; Nolan, Terry M; Wang, Lin-Fa; Deliyannis, Georgia; Purcell, Damian F J; Pouton, Colin W

The mRNA Vaccine Technology Era and the Future Control of Parasitic Infections

mRNA疫苗技术时代与寄生虫感染的未来控制

You, Hong; Jones, Malcolm K; Gordon, Catherine A; Arganda, Alexa E; Cai, Pengfei; Al-Wassiti, Harry; Pouton, Colin W; McManus, Donald P

Delivery and Expression of mRNA in the Secondary Lymphoid Organs Drive Immune Responses to Lipid Nanoparticle-mRNA Vaccines after Intramuscular Injection

肌内注射脂质纳米颗粒-mRNA疫苗后,mRNA在次级淋巴器官中的递送和表达驱动免疫反应

Takanashi, Asuka; Pouton, Colin W; Al-Wassiti, Hareth

Polymeric Nanotubes as Drug Delivery Vectors─Comparison of Covalently and Supramolecularly Assembled Constructs

聚合物纳米管作为药物递送载体——共价组装和超分子组装结构的比较

Kerr, Andrew; Sagita, Erny; Mansfield, Edward D H; Nguyen, Tri-Hung; Feeney, Orlagh M; Pouton, Colin W; Porter, Christopher J H; Sanchis, Joaquin; Perrier, Sébastien