日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A model for Crohn's disease post-ileal resection fibrosis development using human ileal enteroids and myofibroblasts

利用人回肠类器官和肌成纤维细胞构建克罗恩病回肠切除术后纤维化发展模型

Yoo, Jun Hwan; Choi, Yoon Jeong; Pinchuk, Iryna V; Powell, Don W; Zachos, Nicholas C; Donowitz, Mark

IMMU-68. Glioblastoma co-opts dural nociceptors to drive immune evasion and immunotherapy resistance

IMMU-68。胶质母细胞瘤利用硬脑膜伤害感受器来驱动免疫逃逸和免疫治疗耐药。

Zhong, Xiaoying S; Lopez, Kevin M; Krishnachaitanya, Srikruthi S; Liu, Max; Xiao, Ying; Ou, Rongliwen; Nagy, Hania I; Kochkarian, Thierry; Powell, Don W; Fujise, Ken; Li, Qingjie; Asalla, Suman; Ahumada, Omar Santiagonuez; Krull, Jordan; Wang, Yan; Patel, Disha; Liu, Tom; Prasanna, Samiksha; Jerome, Andrew; Chen, Shuo; Wieland, Andreas; Giglio, Pierre; Segal, Benjamin; Ma, Qin; Acharya, Nandini

Erlotinib suppresses tumorigenesis in a mouse model of colitis-associated cancer.

厄洛替尼可抑制结肠炎相关癌症小鼠模型中的肿瘤发生

Liu Max, Zhong Xiaoying S, Krishnachaitanya Srikruthi S, Ou Rongliwen, Dashwood Roderick H, Powell Don W, Li Qingjie

Mechanical stress-induced connective tissue growth factor plays a critical role in intestinal fibrosis in Crohn's-like colitis

机械应力诱导的结缔组织生长因子在克罗恩样结肠炎的肠道纤维化中起着关键作用

Lin, You-Min; Zhang, Ke; Geesala, Ramasatyaveni; Lipson, Kenneth E; Qiu, Suimin; Powell, Don W; Cohn, Steven; Shi, Xuan-Zheng

Cardiovascular manifestations of inflammatory bowel diseases and the underlying pathogenic mechanisms

炎症性肠病的心血管表现及其潜在发病机制

Xiao, Ying; Powell, Don W; Liu, Xiaowei; Li, Qingjie

Disruption of retinol-mediated IL-6 expression in colon cancer-associated fibroblasts: new perspectives on the role of vitamin A metabolism

视黄醇介导的IL-6表达在结肠癌相关成纤维细胞中的紊乱:维生素A代谢作用的新视角

Villéger, Romain; Chulkina, Marina; Mifflin, Randy C; Powell, Don W; Pinchuk, Irina V

Neonatal Colonic Inflammation Epigenetically Aggravates Epithelial Inflammatory Responses to Injury in Adult Life.

新生儿结肠炎症通过表观遗传机制加剧成年后上皮细胞对损伤的炎症反应

Zhong Xiaoying S, Winston John H, Luo Xiuju, Kline Kevin T, Nayeem Syed Z, Cong Yingzi, Savidge Tor C, Dashwood Roderick H, Powell Don W, Li Qingjie

Expression of Programmed Death-Ligand 1 by Human Colonic CD90(+) Stromal Cells Differs Between Ulcerative Colitis and Crohn's Disease and Determines Their Capacity to Suppress Th1 Cells

人结肠CD90(+)基质细胞表达程序性死亡配体1在溃疡性结肠炎和克罗恩病中存在差异,并决定了其抑制Th1细胞的能力。

Beswick, Ellen J; Grim, Carl; Singh, Abinav; Aguirre, Jose E; Tafoya, Marissa; Qiu, Suimin; Rogler, Gerhard; McKee, Rohini; Samedi, Von; Ma, Thomas Y; Reyes, Victor E; Powell, Don W; Pinchuk, Irina V

CD90(+) stromal cells are the major source of IL-6, which supports cancer stem-like cells and inflammation in colorectal cancer

CD90(+)基质细胞是IL-6的主要来源,IL-6支持结直肠癌中的癌干细胞样细胞和炎症反应。

Huynh, Phuong T; Beswick, Ellen J; Coronado, Yun A; Johnson, Paul; O'Connell, Malaney R; Watts, Tammara; Singh, Pomila; Qiu, Suimin; Morris, Katherine; Powell, Don W; Pinchuk, Irina V

Isolation of CD 90+ Fibroblast/Myofibroblasts from Human Frozen Gastrointestinal Specimens

从人冷冻胃肠道标本中分离CD90+成纤维细胞/肌成纤维细胞

Johnson, Paul; Beswick, Ellen J; Chao, Celia; Powell, Don W; Hellmich, Mark R; Pinchuk, Iryna V