日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Characterization of intact mRNA-based therapeutics by charge detection mass spectrometry and mass photometry

利用电荷检测质谱和质谱光度法对完整的mRNA基治疗药物进行表征

Deslignière, Evolène; Barnes, Lauren F; Powers, Thomas W; Friese, Olga V; Heck, Albert J R

Development and implementation of an LC-MS-based multi-attribute method for adeno-associated virus.

开发和实施基于液相色谱-质谱联用技术的腺相关病毒多属性检测方法

Powers Thomas W, Mariani Shawn, Narepekha Halyna, Ryan Daniel, Sankar Savita, Lerch Thomas F

Enabling icIEF Peak Identification of AAV Capsid Proteins by Fractionation on MauriceFlex and Subsequent Analysis by LC-MS.

利用 MauriceFlex 进行分级分离,实现 AAV 衣壳蛋白的 icIEF 峰识别,并随后通过 LC-MS 进行分析

McElroy Will, Huang Sisi, He Xiaoping, Zhou Cheng, Heger Christopher D, Powers Thomas W, Anderson Melissa M, Sloan Courtney, Lerch Thomas F

Implementing a robust platform analytical procedure for measuring adeno-associated virus vector genome titer

实施一种稳健的平台分析程序,用于测量腺相关病毒载体基因组滴度

Powers, Thomas W; Sloan, Courtney D K; Stano, Don; Evans, Brad; Liu, Kang; Mariani, Shawn; Campbell, Jessica A; Lerch, Thomas F; Mo, Jim J

Development of an icIEF assay for monitoring AAV capsid proteins and application to gene therapy products

开发用于监测AAV衣壳蛋白的icIEF检测方法及其在基因治疗产品中的应用

He, Xiaoping Z; Powers, Thomas W; Huang, Sisi; Liu, Zhenjiu; Shi, Heliang; Orlet, John D; Mo, Jim J; Srinivasan, Saipraveen; Jacobs, Steven; Zhang, Kun; Runnels, Herbert A; Anderson, Melissa M; Lerch, Thomas F

Identification of Recombinant Chimpanzee Adenovirus C68 Degradation Products Detected by AEX-HPLC

利用AEX-HPLC检测重组黑猩猩腺病毒C68降解产物的鉴定

Powers, Thomas W; Mullins, Elise K; Zhang, Kun; Binder, Joseph J; Friese, Olga; Runnels, Herbert A; Thompson, Lawrence C

Enhancing the multi-attribute method through an automated and high-throughput sample preparation

通过自动化高通量样品制备增强多属性分析方法

Sitasuwan, Pongkwan; Powers, Thomas W; Medwid, Tiffany; Huang, Yuting; Bare, Bradley; Lee, L Andrew

Imaging Mass Spectrometry and Lectin Analysis of N-Linked Glycans in Carbohydrate Antigen-Defined Pancreatic Cancer Tissues

利用成像质谱和凝集素分析法检测碳水化合物抗原定义的胰腺癌组织中的N-连接糖链

McDowell, Colin T; Klamer, Zachary; Hall, Johnathan; West, Connor A; Wisniewski, Luke; Powers, Thomas W; Angel, Peggi M; Mehta, Anand S; Lewin, David N; Haab, Brian B; Drake, Richard R

Comparison of analytical techniques to quantitate the capsid content of adeno-associated viral vectors

腺相关病毒载体衣壳含量定量分析技术的比较

Werle, Amanda K; Powers, Thomas W; Zobel, James F; Wappelhorst, Caitlin N; Jarrold, Martin F; Lyktey, Nicholas A; Sloan, Courtney D K; Wolf, Andrew J; Adams-Hall, Sharee; Baldus, Phoebe; Runnels, Herbert A

Quantitative analysis of genome packaging in recombinant AAV vectors by charge detection mass spectrometry.

利用电荷检测质谱法对重组AAV载体中的基因组包装进行定量分析。

Barnes Lauren F, Draper Benjamin E, Chen Yu-Ting, Powers Thomas W, Jarrold Martin F