日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural basis for the association of PLEKHA7 with membrane-embedded phosphatidylinositol lipids

PLEKHA7与膜内磷脂酰肌醇脂质结合的结构基础

Aleshin, Alexander E; Yao, Yong; Iftikhar, Amer; Bobkov, Andrey A; Yu, Jinghua; Cadwell, Gregory; Klein, Michael G; Dong, Chuqiao; Bankston, Laurie A; Liddington, Robert C; Im, Wonpil; Powis, Garth; Marassi, Francesca M

PLEKHA7 signaling is necessary for the growth of mutant KRAS driven colorectal cancer

PLEKHA7信号通路对于突变型KRAS驱动的结直肠癌的生长是必需的。

Jeung, Hei-Cheul; Puentes, Roisin; Aleshin, Alexander; Indarte, Martin; Correa, Ricardo G; Bankston, Laurie A; Layng, Fabiana I A L; Ahmed, Zamal; Wistuba, Ignacio; Yao, Yong; Duenas, Daniela G; Zhang, Shuxing; Meuillet, Emmanuelle J; Marassi, Francesca; Liddington, Robert C; Kirkpatrick, Lynn; Powis, Garth

Modeling of Patient-Derived Xenografts in Colorectal Cancer

结直肠癌患者来源异种移植模型

Katsiampoura, Anastasia; Raghav, Kanwal; Jiang, Zhi-Qin; Menter, David G; Varkaris, Andreas; Morelli, Maria P; Manuel, Shanequa; Wu, Ji; Sorokin, Alexey V; Rizi, Bahar Salimian; Bristow, Christopher; Tian, Feng; Airhart, Susan; Cheng, Mingshan; Broom, Bradley M; Morris, Jeffrey; Overman, Michael J; Powis, Garth; Kopetz, Scott

Definition of a Novel Feed-Forward Mechanism for Glycolysis-HIF1α Signaling in Hypoxic Tumors Highlights Aldolase A as a Therapeutic Target

缺氧肿瘤中糖酵解-HIF1α信号传导新型前馈机制的定义凸显了醛缩酶A作为治疗靶点的重要性

Grandjean, Geoffrey; de Jong, Petrus R; James, Brian; Koh, Mei Yee; Lemos, Robert; Kingston, John; Aleshin, Alexander; Bankston, Laurie A; Miller, Claudia P; Cho, Eun Jeong; Edupuganti, Ramakrishna; Devkota, Ashwini; Stancu, Gabriel; Liddington, Robert C; Dalby, Kevin; Powis, Garth

Improving gastric cancer preclinical studies using diverse in vitro and in vivo model systems

利用多种体外和体内模型系统改进胃癌临床前研究

Chang, Hae Ryung; Park, Hee Seo; Ahn, Young Zoo; Nam, Seungyoon; Jung, Hae Rim; Park, Sungjin; Lee, Sang Jin; Balch, Curt; Powis, Garth; Ku, Ja-Lok; Kim, Yon Hui

Phase II Pilot Study of Vemurafenib in Patients With Metastatic BRAF-Mutated Colorectal Cancer

维莫非尼治疗BRAF突变转移性结直肠癌患者的II期试点研究

Kopetz, Scott; Desai, Jayesh; Chan, Emily; Hecht, Joel Randolph; O'Dwyer, Peter J; Maru, Dipen; Morris, Van; Janku, Filip; Dasari, Arvind; Chung, Woonbook; Issa, Jean-Pierre J; Gibbs, Peter; James, Brian; Powis, Garth; Nolop, Keith B; Bhattacharya, Suman; Saltz, Leonard

The effect of disintegrin-metalloproteinase ADAM9 in gastric cancer progression

解整合素金属蛋白酶ADAM9在胃癌进展中的作用

Kim, Jeong Min; Jeung, Hei-Cheul; Rha, Sun Young; Yu, Eun Jeong; Kim, Tae Soo; Shin, You Keun; Zhang, Xianglan; Park, Kyu Hyun; Park, Seung Woo; Chung, Hyun Cheol; Powis, Garth

AMPKα modulation in cancer progression: multilayer integrative analysis of the whole transcriptome in Asian gastric cancer

AMPKα调控在癌症进展中的作用:亚洲胃癌全转录组的多层整合分析

Kim, Yon Hui; Liang, Han; Liu, Xiuping; Lee, Ju-Seog; Cho, Jae Yong; Cheong, Jae-Ho; Kim, Hoguen; Li, Min; Downey, Thomas J; Dyer, Matthew D; Sun, Yongming; Sun, Jingtao; Beasley, Ellen M; Chung, Hyun Cheol; Noh, Sung Hoon; Weinstein, John N; Liu, Chang-Gong; Powis, Garth

Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcome.

KRAS癌基因替换对蛋白质行为的影响:对信号传导和临床结果的意义

Ihle Nathan T, Byers Lauren A, Kim Edward S, Saintigny Pierre, Lee J Jack, Blumenschein George R, Tsao Anne, Liu Suyu, Larsen Jill E, Wang Jing, Diao Lixia, Coombes Kevin R, Chen Lu, Zhang Shuxing, Abdelmelek Mena F, Tang Ximing, Papadimitrakopoulou Vassiliki, Minna John D, Lippman Scott M, Hong Waun K, Herbst Roy S, Wistuba Ignacio I, Heymach John V, Powis Garth

Tumor Xenograft Response to Redox-Active Therapies Assessed by Magnetic Resonance Imaging Using a Thiol-Bearing DOTA Complex of Gadolinium

利用含硫醇的钆DOTA复合物进行磁共振成像,评估肿瘤异种移植对氧化还原活性疗法的反应

Guntle, Gerald P; Jagadish, Bhumasamudram; Mash, Eugene A; Powis, Garth; Dorr, Robert T; Raghunand, Natarajan