日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cryo-EM Structures Reveal the Molecular Basis of Asymmetric Allosteric Activation by MMOB in the Hydroxylase of Soluble Methane Monooxygenase

冷冻电镜结构揭示了MMOB对可溶性甲烷单加氧酶羟化酶不对称变构激活的分子基础

Hwang, Yunha; Ryu, Bumhan; Park, Soyeon; Lee, Dong-Heon; Hong, Hyo Jin; Na, Jeong-Geol; Song, Chul Gyu; Kang, Hyun Goo; Pozharski, Edwin; Lee, Seung Jae

Rational design of flavivirus E protein vaccine optimizes immunogenicity and mitigates antibody dependent enhancement risk.

黄病毒E蛋白疫苗的合理设计可优化免疫原性并降低抗体依赖性增强风险。

Wang Yimeng, Galkin Andrey, Shang Xiaoran, Marin Alexander, Jin Shaohua, Ye Ting-Juan, Bale Shridhar, Chiang Chi-I, Chowdhury Ananda, Chenine Agnes L, Turonis Ashley, Greenhouse Jack, Stone Rebecca, Wear Jaclyn, Kar Swagata, Andersen Hanne, Huang Yan-Jang S, Vanlandingham Dana L, Higgs Stephen, Lapidus Rena G, Fuerst Thomas, Weber David J, Wyatt Richard T, Iffland Christel, Pierson Theodore C, Andrianov Alexander K, Pozharski Edwin, Li Yuxing

Pore formation by the CDTb component of the Clostridioides difficile binary toxin is Ca(2+)-dependent

艰难梭菌二元毒素 CDTb 组分的成孔作用依赖于 Ca²⁺。

Abeyawardhane, Dinendra L; Sevdalis, Spiridon E; Adipietro, Kaylin A; Godoy-Ruiz, Raquel; Varney, Kristen M; Nawaz, Izza F; Spittel, Alejandro X; Hunter, Daniel; Rustandi, Richard R; Silin, Vitalii I; des Georges, Amedee; Cook, Mary E; Pozharski, Edwin; Weber, David J

Structural and Functional Insights into the Delivery Systems of Bacillus and Clostridial Binary Toxins

芽孢杆菌和梭菌二元毒素递送系统的结构和功能研究

Sevdalis, Spiridon E; Varney, Kristen M; Cook, Mary E; Gillespie, Joseph J; Pozharski, Edwin; Weber, David J

The Importance of Therapeutically Targeting the Binary Toxin from Clostridioides difficile

治疗性靶向艰难梭菌二元毒素的重要性

Abeyawardhane, Dinendra L; Godoy-Ruiz, Raquel; Adipietro, Kaylin A; Varney, Kristen M; Rustandi, Richard R; Pozharski, Edwin; Weber, David J

A plasmid borne, functionally novel glycoside hydrolase family 30 subfamily 8 endoxylanase from solventogenic Clostridium

来自产溶剂梭菌的质粒携带的新型糖苷水解酶30亚家族8内切木聚糖酶

St John, Franz J; Dietrich, Diane; Crooks, Casey; Balogun, Peter; de Serrano, Vesna; Pozharski, Edwin; Smith, James Kennon; Bales, Elizabeth; Hurlbert, Jason

Detect, correct, retract: How to manage incorrect structural models

检测、纠正、撤回:如何管理不正确的结构模型

Wlodawer, Alexander; Dauter, Zbigniew; Porebski, Przemyslaw J; Minor, Wladek; Stanfield, Robyn; Jaskolski, Mariusz; Pozharski, Edwin; Weichenberger, Christian X; Rupp, Bernhard

Twilight reloaded: the peptide experience

暮光重装上阵:肽体验

Weichenberger, Christian X; Pozharski, Edwin; Rupp, Bernhard

Crystal structures of human 3-hydroxyanthranilate 3,4-dioxygenase with native and non-native metals bound in the active site

人3-羟基邻氨基苯甲酸3,4-双加氧酶的晶体结构,活性位点结合天然和非天然金属

Pidugu, Lakshmi Swarna Mukhi; Neu, Heather; Wong, Tin Lok; Pozharski, Edwin; Molloy, John L; Michel, Sarah L J; Toth, Eric A

Crystal structure of the human heterogeneous ribonucleoprotein A18 RNA-recognition motif

人类异质核糖核蛋白A18 RNA识别基序的晶体结构

Coburn, Katherine; Melville, Zephan; Aligholizadeh, Ehson; Roth, Braden M; Varney, Kristen M; Carrier, France; Pozharski, Edwin; Weber, David J