日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

DNA-encoded chemical libraries yield non-covalent and non-peptidic SARS-CoV-2 main protease inhibitors

DNA 编码化学库产生非共价和非肽类 SARS-CoV-2 主要蛋白酶抑制剂

期刊:Communications Chemistry
影响因子:5.9
doi:10.1038/s42004-023-00961-y
Ravikumar Jimmidi #, Srinivas Chamakuri #, Shuo Lu #, Melek Nihan Ucisik, Peng-Jen Chen, Kurt M Bohren, Seyed Arad Moghadasi, Leroy Versteeg, Christina Nnabuife, Jian-Yuan Li, Xuan Qin, Ying-Chu Chen, John C Faver, Pranavanand Nyshadham, Kiran L Sharma, Banumathi Sankaran, Allison Judge, Zhifeng Yu,
代谢
免疫
心血管
新冠
发表日期：2023
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Discovery of potent BET bromodomain 1 stereoselective inhibitors using DNA-encoded chemical library selections

利用DNA编码化学库筛选发现强效BET溴结构域1立体选择性抑制剂

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2122506119
Modukuri, Ram K; Yu, Zhifeng; Tan, Zhi; Ta, Hai Minh; Ucisik, Melek Nihan; Jin, Zhuang; Anglin, Justin L; Sharma, Kiran L; Nyshadham, Pranavanand; Li, Feng; Riehle, Kevin; Faver, John C; Duong, Kevin; Nagarajan, Sureshbabu; Simmons, Nicholas; Palmer, Stephen S; Teng, Mingxing; Young, Damian W; Yi, Joanna S; Kim, Choel; Matzuk, Martin M
发表日期：2022
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Discovery and characterization of bromodomain 2-specific inhibitors of BRDT

BRDT溴结构域2特异性抑制剂的发现与表征

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2021102118
Yu, Zhifeng; Ku, Angela F; Anglin, Justin L; Sharma, Rajesh; Ucisik, Melek Nihan; Faver, John C; Li, Feng; Nyshadham, Pranavanand; Simmons, Nicholas; Sharma, Kiran L; Nagarajan, Sureshbabu; Riehle, Kevin; Kaur, Gundeep; Sankaran, Banumathi; Storl-Desmond, Marta; Palmer, Stephen S; Young, Damian W; Kim, Choel; Matzuk, Martin M
发表日期：2021
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DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 M(pro) inhibitors.

DNA编码化学技术可快速获得SARS-CoV-2 M(pro)抑制剂

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2111172118
Chamakuri Srinivas, Lu Shuo, Ucisik Melek Nihan, Bohren Kurt M, Chen Ying-Chu, Du Huang-Chi, Faver John C, Jimmidi Ravikumar, Li Feng, Li Jian-Yuan, Nyshadham Pranavanand, Palmer Stephen S, Pollet Jeroen, Qin Xuan, Ronca Shannon E, Sankaran Banumathi, Sharma Kiran L, Tan Zhi, Versteeg Leroy, Yu Zhifeng, Matzuk Martin M, Palzkill Timothy, Young Damian W
信号转导
新冠
发表日期：2021
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Discovery of potent thrombin inhibitors from a protease-focused DNA-encoded chemical library

从以蛋白酶为靶点的DNA编码化合物库中发现强效凝血酶抑制剂

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2005447117
Dawadi, Surendra; Simmons, Nicholas; Miklossy, Gabriella; Bohren, Kurt M; Faver, John C; Ucisik, Melek Nihan; Nyshadham, Pranavanand; Yu, Zhifeng; Matzuk, Martin M
发表日期：2020
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Mammalian Target of Rapamycin Complex 2 Signaling Is Required for Liver Regeneration in a Cholestatic Liver Injury Murine Model

在胆汁淤积性肝损伤小鼠模型中，雷帕霉素靶蛋白复合物2信号传导是肝脏再生所必需的

期刊:American Journal of Pathology
影响因子:4.7
doi:10.1016/j.ajpath.2020.03.010
Yi Zhou ，Meng Xu ，Pin Liu ，Binyong Liang ，Manning Qian ，Haichuan Wang ，Xinhua Song ，Pranavanand Nyshadham ，Li Che ，Diego F Calvisi ，Feng Li ，Shumei Lin ，Xin Chen
肝损伤
毒理研究
信号转导
发表日期：2020
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Identifying Oxacillinase-48 Carbapenemase Inhibitors Using DNA-Encoded Chemical Libraries

利用DNA编码化合物库鉴定奥沙西林酶-48碳青霉烯酶抑制剂

期刊:ACS Infectious Diseases
影响因子:3.8
doi:10.1021/acsinfecdis.0c00015
Taylor, Doris Mia; Anglin, Justin; Park, Suhyeorn; Ucisik, Melek N; Faver, John C; Simmons, Nicholas; Jin, Zhuang; Palaniappan, Murugesan; Nyshadham, Pranavanand; Li, Feng; Campbell, James; Hu, Liya; Sankaran, Banumathi; Prasad, B V Venkataram; Huang, Hongbing; Matzuk, Martin M; Palzkill, Timothy
发表日期：2020
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Homogeneous and Functional Group Tolerant Ring-Closing Metathesis for DNA-Encoded Chemical Libraries

用于DNA编码化学库的均相和官能团耐受的闭环复分解反应

期刊:ACS Combinatorial Science
影响因子:
doi:10.1021/acscombsci.9b00199
Monty, Olivier B C; Nyshadham, Pranavanand; Bohren, Kurt M; Palaniappan, Murugesan; Matzuk, Martin M; Young, Damian W; Simmons, Nicholas
HTRF
发表日期：2020
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