日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genomic enrichment and functional impact of TP53 and CYLD alterations in recurrent and metastatic HPV-associated head and neck cancer

TP53和CYLD基因改变在复发性和转移性HPV相关头颈癌中的基因组富集和功能影响

Prasad, Manu; Cheng, Alex T; Mayer, Marcel; Jansen, Louis; Koh, Elizabeth; Nadeem, Zaineb; Sivan Pillai, Gopika; Vos, Joris; Kuo, Fengshen; Zhao, Karena; Sfreddo, Hannah J; Lee, Andrew; Chen, Siqi; Schloss, Jennifer; Deng, Xinzhu; Jain, Swati; Muldoon, Daniel; Bandlamudi, Chaitanya; Klussmann, Jens Peter; Ow, Thomas J; Ho, Alan L; Lee, Nancy Y; Riaz, Nadeem; Wong, Richard J; Ganly, Ian; Katabi, Nora; Morris, Luc G T

Longitudinal and multisite sampling reveals mutational and copy number evolution in tumors during metastatic dissemination

纵向和多点取样揭示了转移扩散过程中肿瘤的突变和拷贝数演变

Zhao, Karena; Vos, Joris; Lam, Stanley; Boe, Lillian A; Muldoon, Daniel; Han, Catherine Y; Valero, Cristina; Lee, Mark; Fitzgerald, Conall; Lee, Andrew S; Prasad, Manu; Jain, Swati; Deng, Xinzhu; Chan, Timothy A; Berger, Michael F; Bandlamudi, Chaitanya; Zhou, Xi Kathy; Morris, Luc G T

Anti-PD1 prolongs the response of PI3K and farnesyl transferase inhibition in HRAS- and PIK3CA-mutant head and neck cancers.

抗 PD-1 可延长 HRAS 和 PIK3CA 突变型头颈癌中 PI3K 和法尼基转移酶抑制剂的反应时间

Manikandan Dinesh Babu, Jagadeeshan Sankar, Mathukkada Sooraj, Shareb Raghda Abu, Prasad Manu, Belsamma Liju Vijaya Steltar, Marripati Divyasree, Erez Noga, Wainer Monica, Geva Amit, Raviv Danielle, Allon Irit, Morris Luc Gt, Su Gloria H, Wang Hai, Rosenberg Ari J, Kessler Linda, Burrows Francis, Elkabets Moshe

MEK1/2 inhibition transiently alters the tumor immune microenvironment to enhance immunotherapy efficacy against head and neck cancer

MEK1/2抑制剂可暂时改变肿瘤免疫微环境,从而增强免疫疗法对头颈癌的疗效。

Prasad, Manu; Zorea, Jonathan; Jagadeeshan, Sankar; Shnerb, Avital B; Mathukkada, Sooraj; Bouaoud, Jebrane; Michon, Lucas; Novoplansky, Ofra; Badarni, Mai; Cohen, Limor; Yegodayev, Ksenia M; Tzadok, Sapir; Rotblat, Barak; Brezina, Libor; Mock, Andreas; Karabajakian, Andy; Fayette, Jérôme; Cohen, Idan; Cooks, Tomer; Allon, Irit; Dimitstein, Orr; Joshua, Benzion; Kong, Dexin; Voronov, Elena; Scaltriti, Maurizio; Carmi, Yaron; Conde-Lopez, Cristina; Hess, Jochen; Kurth, Ina; Morris, Luc G T; Saintigny, Pierre; Elkabets, Moshe

Genome-wide copy number scan identifies IRF6 involvement in Van der Woude syndrome in an Indian family

全基因组拷贝数扫描发现IRF6参与了印度一个家族的范德伍德综合征。

Manjegowda, Dinesh S; Prasad, Manu; Veerappa, Avinash M; Ramachandra, Nallur B