Prat Annik相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Blockade of colon cancer metastasis via single and double silencing of PCSK7/PCSK9: enhanced T cells cytotoxicity in mouse and human

通过单基因或双基因沉默PCSK7/PCSK9阻断结肠癌转移：增强小鼠和人类T细胞的细胞毒性

期刊:Journal for ImmunoTherapy of Cancer

影响因子:10.6

doi:10.1136/jitc-2024-011364

Porcheron, Chloé; Le Devehat, Mailys; Roubtsova, Anna; Bayat, Hadi; Evagelidis, Alexandra; Jafarzadeh, Leila; Sachan, Vatsal; Labrecque, Nathalie; Fonta Holder, Alexie; Susan-Resiga, Delia; Essalmani, Rachid; Boudreau, Gabrielle; Prat, Annik; Cusseddu, Rebecca; Côté, Jean-François; Khatib, Abdel-Majid; Delisle, Jean-Sébastien; Seidah, Nabil G

细胞生物学

免疫/内分泌

发表日期：2025

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Molecular interactions of PCSK9 with an inhibitory nanobody, CAP1 and HLA-C: Functional regulation of LDLR levels.

PCSK9 与抑制性纳米抗体、CAP1 和 HLA-C 的分子相互作用：LDLR 水平的功能调节

期刊:Molecular Metabolism

影响因子:6.6

doi:10.1016/j.molmet.2022.101662

Fruchart Gaillard Carole, Ouadda Ali Ben Djoudi, Ciccone Lidia, Girard Emmanuelle, Mikaeeli Sepideh, Evagelidis Alexandra, Le DÃ©vÃ©hat MaÃ¯lys, Susan-Resiga Delia, Lajeunesse Evelyne Cassar, Nozach HervÃ©, Ramos Oscar Henrique Pereira, Thureau AurÃ©lien, Legrand Pierre, Prat Annik, Dive Vincent, Seidah Nabil G

发表日期：2023

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The Multifaceted Biology of PCSK9

PCSK9的多面生物学特性

期刊:Endocrine Reviews

影响因子:22

doi:10.1210/endrev/bnab035

Seidah, Nabil G; Prat, Annik

发表日期：2022

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Sortilin enhances secretion of apolipoprotein(a) through effects on apolipoprotein B secretion and promotes uptake of lipoprotein(a).

Sortilin 通过影响载脂蛋白 B 的分泌来增强载脂蛋白 (a) 的分泌，并促进脂蛋白 (a) 的吸收

期刊:Journal of Lipid Research

影响因子:4.1

doi:10.1016/j.jlr.2022.100216

Clark Justin R, Gemin Matthew, Youssef Amer, Marcovina Santica M, Prat Annik, Seidah Nabil G, Hegele Robert A, Boffa Michael B, Koschinsky Marlys L

发表日期：2022

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Circulating PCSK9 is associated with liver biomarkers and hepatic steatosis

循环PCSK9与肝脏生物标志物和肝脂肪变性相关。

期刊:Clinical Biochemistry

影响因子:2.1

doi:10.1016/j.clinbiochem.2020.01.003

Paquette, Martine; Gauthier, Dany; Chamberland, Ann; Prat, Annik; De Lucia Rolfe, Emanuella; Rasmussen, Jon J; Kaduka, Lydia; Seidah, Nabil G; Bernard, Sophie; Christensen, Dirk L; Baass, Alexis

发表日期：2020

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Pcsk9 knockout exacerbates diet-induced non-alcoholic steatohepatitis, fibrosis and liver injury in mice

PCSK9基因敲除会加剧小鼠饮食诱导的非酒精性脂肪性肝炎、肝纤维化和肝损伤。

期刊:Jhep Reports

影响因子:7.5

doi:10.1016/j.jhepr.2019.10.009

Lebeau, Paul F; Byun, Jae Hyun; Platko, Khrystyna; Al-Hashimi, Ali A; Lhoták, Šárka; MacDonald, Melissa E; Mejia-Benitez, Aurora; Prat, Annik; Igdoura, Suleiman A; Trigatti, Bernardo; Maclean, Kenneth N; Seidah, Nabil G; Austin, Richard C

发表日期：2019

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Transcriptome Analysis Reveals Nonfoamy Rather Than Foamy Plaque Macrophages Are Proinflammatory in Atherosclerotic Murine Models

转录组分析揭示，在动脉粥样硬化小鼠模型中，非泡沫型而非泡沫型斑块巨噬细胞具有促炎作用

期刊:Circulation Research

影响因子:16.2

doi:10.1161/CIRCRESAHA.118.312804

Kim, Kyeongdae; Shim, Dahee; Lee, Jun Seong; Zaitsev, Konstantin; Williams, Jesse W; Kim, Ki-Wook; Jang, Man-Young; Seok Jang, Hyung; Yun, Tae Jin; Lee, Seung Hyun; Yoon, Won Kee; Prat, Annik; Seidah, Nabil G; Choi, Jungsoon; Lee, Seung-Pyo; Yoon, Sang-Ho; Nam, Jin Wu; Seong, Je Kyung; Oh, Goo Taeg; Randolph, Gwendalyn J; Artyomov, Maxim N; Cheong, Cheolho; Choi, Jae-Hoon

细胞生物学

动脉粥样硬化

免疫/内分泌

发表日期：2018

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Thrombin activation of protein C requires prior processing by a liver proprotein convertase

凝血酶激活蛋白C需要先经肝脏前蛋白转化酶加工。

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1074/jbc.M116.770040

Essalmani, Rachid; Susan-Resiga, Delia; Guillemot, Johann; Kim, Woojin; Sachan, Vatsal; Awan, Zuhier; Chamberland, Ann; Asselin, Marie-Claude; Ly, Kévin; Desjardins, Roxane; Day, Robert; Prat, Annik; Seidah, Nabil G

发表日期：2017

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Pcsk5 is required in the early cranio-cardiac mesoderm for heart development

PCSK5在早期颅心中胚层中对心脏发育是必需的

期刊:BMC Developmental Biology

doi:10.1186/s12861-017-0148-y

Szumska, Dorota; Cioroch, Milena; Keeling, Angela; Prat, Annik; Seidah, Nabil G; Bhattacharya, Shoumo

发育与干细胞

发表日期：2017

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Proprotein convertase subtilisin/Kexin type 9 (PCSK9) single domain antibodies are potent inhibitors of low density lipoprotein receptor degradation

前蛋白转化酶枯草杆菌蛋白酶/Kexin 9型（PCSK9）单域抗体是低密度脂蛋白受体降解的强效抑制剂。

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1074/jbc.A116.717736

Weider, Elodie; Susan-Resiga, Delia; Essalmani, Rachid; Hamelin, Josée; Asselin, Marie-Claude; Nimesh, Surendra; Ashraf, Yahya; Wycoff, Keith L; Zhang, Jianbing; Prat, Annik; Seidah, Nabil G

发表日期：2016

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