文献库，生知库 | 链接生命科学的每一步

Surarapu, Lava Kumar; Tilton, Kevin; Stritto, Maria Rosaria Dello; Acharya, Ananya; Menendez, Andrea Marton; Lu, Min; Shaheen, Najma; Liang, Shun; Iyer, Mythri; Cejka, Petr; Pratto, Florencia; Jain, Devanshi

发表日期：2026

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CNS-targeted base editing of the major late-onset Tay-Sachs mutation alleviates disease in mice.

针对中枢神经系统的主要迟发性泰-萨克斯病突变进行碱基编辑可缓解小鼠的疾病

期刊:Journal of Clinical Investigation

影响因子:13.6

doi:10.1172/JCI183434

Allende Maria L, Kono Mari, Lee Y Terry, Olmsted Samantha M, Huso Vienna, Bakir Jenna Y, Pratto Florencia, Li Cuiling, Byrnes Colleen, Tuymetova Galina, Zhu Hongling, Tifft Cynthia J, Proia Richard L

神经科学

发表日期：2025

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Cataloging Human PRDM9 Allelic Variation Using Long-Read Sequencing Reveals PRDM9 Population Specificity and Two Distinct Groupings of Related Alleles

利用长读长测序技术对人类PRDM9等位基因变异进行编目，揭示了PRDM9的群体特异性以及相关等位基因的两种不同分组。

期刊:Frontiers in Cell and Developmental Biology

影响因子:4.3

doi:10.3389/fcell.2021.675286

Alleva, Benjamin; Brick, Kevin; Pratto, Florencia; Huang, Mini; Camerini-Otero, Rafael Daniel

After the break: DSB end processing in mouse meiosis

休息之后：小鼠减数分裂中的DSB末端处理

期刊:Genes & Development

影响因子:7.7

doi:10.1101/gad.339309.120

Brick, Kevin; Pratto, Florencia; Camerini-Otero, R Daniel

发表日期：2020

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Homologous pairing preceding SPO11-mediated double-strand breaks in mice

小鼠中SPO11介导的双链断裂之前的同源配对

期刊:Developmental Cell

影响因子:8.7

doi:10.1016/j.devcel.2012.12.002

Boateng, Kingsley A; Bellani, Marina A; Gregoretti, Ivan V; Pratto, Florencia; Camerini-Otero, R Daniel

发表日期：2013

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Single-molecule analysis of proteinxDNA complexes formed during partition of newly replicated plasmid molecules in Streptococcus pyogenes

对化脓性链球菌中新复制质粒分子分离过程中形成的蛋白质-DNA复合物进行单分子分析

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1074/jbc.M109.035410

Pratto, Florencia; Suzuki, Yuki; Takeyasu, Kunio; Alonso, Juan C

发表日期：2009

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Streptococcus pyogenes pSM19035 requires dynamic assembly of ATP-bound ParA and ParB on parS DNA during plasmid segregation

化脓性链球菌pSM19035在质粒分离过程中需要将ATP结合的ParA和ParB动态组装到parS DNA上。

期刊:Nucleic Acids Research

影响因子:13.1

doi:10.1093/nar/gkn170

Pratto, Florencia; Cicek, Aslan; Weihofen, Wilhelm A; Lurz, Rudi; Saenger, Wolfram; Alonso, Juan C

发表日期：2008

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Critical roles of MCM8 in meiotic recombination during mouse spermatogenesis

MCM8在小鼠精子发生过程中减数分裂重组中的关键作用

CNS-targeted base editing of the major late-onset Tay-Sachs mutation alleviates disease in mice.

针对中枢神经系统的主要迟发性泰-萨克斯病突变进行碱基编辑可缓解小鼠的疾病

Cataloging Human PRDM9 Allelic Variation Using Long-Read Sequencing Reveals PRDM9 Population Specificity and Two Distinct Groupings of Related Alleles

利用长读长测序技术对人类PRDM9等位基因变异进行编目，揭示了PRDM9的群体特异性以及相关等位基因的两种不同分组。

After the break: DSB end processing in mouse meiosis

休息之后：小鼠减数分裂中的DSB末端处理

Homologous pairing preceding SPO11-mediated double-strand breaks in mice

小鼠中SPO11介导的双链断裂之前的同源配对

Single-molecule analysis of proteinxDNA complexes formed during partition of newly replicated plasmid molecules in Streptococcus pyogenes

对化脓性链球菌中新复制质粒分子分离过程中形成的蛋白质-DNA复合物进行单分子分析

Streptococcus pyogenes pSM19035 requires dynamic assembly of ATP-bound ParA and ParB on parS DNA during plasmid segregation

化脓性链球菌pSM19035在质粒分离过程中需要将ATP结合的ParA和ParB动态组装到parS DNA上。