日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

LyP-1-Modified Oncolytic Adenoviruses Targeting Transforming Growth Factor β Inhibit Tumor Growth and Metastases and Augment Immune Checkpoint Inhibitor Therapy in Breast Cancer Mouse Models

靶向转化生长因子 β 的 LyP-1 修饰溶瘤腺病毒可抑制乳腺癌小鼠模型中的肿瘤生长和转移并增强免疫检查点抑制剂治疗

Weidong Xu, Yuefeng Yang, Zebin Hu, Maria Head, Kathy A Mangold, Megan Sullivan, Edward Wang, Poornima Saha, Kamalakar Gulukota, Donald L Helseth, Theresa Guise, Bellur S Prabhkar, Karen Kaul, Hans Schreiber, Prem Seth

Oncolytic adenovirus targeting TGF-β enhances anti-tumor responses of mesothelin-targeted chimeric antigen receptor T cell therapy against breast cancer

靶向 TGF-β 的溶瘤腺病毒增强间皮素靶向嵌合抗原受体 T 细胞治疗乳腺癌的抗肿瘤反应

Yuxiang Li, Fengjun Xiao, Aimei Zhang, Dan Zhang, Wenbo Nie, Tianxin Xu, Bing Han, Prem Seth, Hua Wang, Yuefeng Yang, Lisheng Wang

Ad5/48 hexon oncolytic virus expressing sTGFβRIIFc produces reduced hepatic and systemic toxicities and inhibits prostate cancer bone metastases

表达 sTGFβRIIFc 的 Ad5/48 六邻体溶瘤病毒可降低肝脏和全身毒性并抑制前列腺癌骨转移

Weidong Xu, Zhenwei Zhang, Yuefeng Yang, Zebin Hu, Chi-Hsiung Wang, Melanie Morgan, Ying Wu, Ryan Hutten, Xianghui Xiao, Stuart Stock, Theresa Guise, Bellur S Prabhakar, Charles Brendler, Prem Seth

Systemic delivery of oncolytic adenoviruses targeting transforming growth factor-β inhibits established bone metastasis in a prostate cancer mouse model

全身性递送靶向转化生长因子-β 的溶瘤腺病毒可抑制前列腺癌小鼠模型中已建立的骨转移

Zebin Hu, Janhavi Gupta, Zhenwei Zhang, Helen Gerseny, Arthur Berg, Yun Ju Chen, Zhiling Zhang, Hongyan Du, Charles B Brendler, Xianghui Xiao, Kenneth J Pienta, Theresa Guise, Chung Lee, Paula H Stern, Stuart Stock, Prem Seth

Oncolytic adenovirus expressing soluble TGFβ receptor II-Fc-mediated inhibition of established bone metastases: a safe and effective systemic therapeutic approach for breast cancer

表达可溶性 TGFβ 受体 II-Fc 的溶瘤腺病毒介导对已建立的骨转移的抑制:一种安全有效的乳腺癌全身治疗方法

Zebin Hu, Helen Gerseny, Zhenwei Zhang, Yun-Ju Chen, Arthur Berg, Zhiling Zhang, Stuart Stock, Prem Seth