日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Supplementing Glycine and N-Acetylcysteine (GlyNAC) in Older Adults Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Physical Function, and Aging Hallmarks: A Randomized Clinical Trial.

一项随机临床试验表明，老年人补充甘氨酸和 N-乙酰半胱氨酸 (GlyNAC) 可改善谷胱甘肽缺乏、氧化应激、线粒体功能障碍、炎症、身体机能和衰老特征

期刊:Journals of Gerontology Series A-Biological Sciences and Medical Sciences
影响因子:3.8
doi:10.1093/gerona/glac135
Kumar Premranjan, Liu Chun, Suliburk James, Hsu Jean W, Muthupillai Raja, Jahoor Farook, Minard Charles G, Taffet George E, Sekhar Rajagopal V
炎症/感染
氧化应激
炎症
线粒体
发表日期：2023
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GlyNAC (Glycine and N-Acetylcysteine) Supplementation in Old Mice Improves Brain Glutathione Deficiency, Oxidative Stress, Glucose Uptake, Mitochondrial Dysfunction, Genomic Damage, Inflammation and Neurotrophic Factors to Reverse Age-Associated Cognitive Decline: Implications for Improving Brain Health in Aging

老年小鼠补充 GlyNAC（甘氨酸和 N-乙酰半胱氨酸）可改善大脑谷胱甘肽缺乏症、氧化应激、葡萄糖摄取、线粒体功能障碍、基因组损伤、炎症和神经营养因子，从而逆转与年龄相关的认知能力下降：对改善衰老大脑健康的意义

期刊:Antioxidants
影响因子:
doi:10.3390/antiox12051042
Premranjan Kumar, Ob W Osahon, Rajagopal V Sekhar
神经
Senescence
发表日期：2023
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GLYNAC SUPPLEMENTATION IN OLDER ADULTS PROTECTS FROM MEAL DRIVEN OXIDATIVE STRESS AND INFLAMMATION: RESULTS OF A RCT

一项随机对照试验结果表明，老年人补充格列那酸可预防餐后氧化应激和炎症：

期刊:International Journal of Biological Sciences
影响因子:10
doi:10.7150/ijbs.56952
Hu, Qin; Xu, Yu; Xiang, Ying; Wang, Bin; Yuan, Zhiquan; Shan, Yifan; Zhang, Wenjing; Wu, Na; Xia, Tingting; Li, Chengying; Xie, Weijia; Jia, Xiaoyue; Yu, Zubin; Bai, Li; Li, Yafei; Qian, Xiao; Xiao, Qian; Evans, Daniel S; Redline, Susan; Lane, Nancy; Ancoli-Israel, Sonia; Stone, Katie S; Sekhar, Rajagopal; Taffet, George; Kumar, Premranjan
炎症/感染
毒理研究
炎症
氧化应激
发表日期：2022
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GlyNAC (Glycine and N-Acetylcysteine) Supplementation in Mice Increases Length of Life by Correcting Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Abnormalities in Mitophagy and Nutrient Sensing, and Genomic Damage

小鼠补充 GlyNAC（甘氨酸和 N-乙酰半胱氨酸）可通过纠正谷胱甘肽缺乏、氧化应激、线粒体功能障碍、线粒体自噬和营养感应异常以及基因组损伤来延长寿命

期刊:Nutrients
影响因子:4.8
doi:10.3390/nu14051114
Premranjan Kumar, Ob W Osahon, Rajagopal V Sekhar
表观遗传
发表日期：2022
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Mechanistic Role of Jak3 in Obesity-Associated Cognitive Impairments

Jak3在肥胖相关认知障碍中的机制作用

期刊:Nutrients
影响因子:4.8
doi:10.3390/nu14183715
Premranjan Kumar ，Jayshree Mishra ，Narendra Kumar
肥胖
代谢
神经科学
发表日期：2022
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Glycine and N-acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity, muscle strength, and cognition: Results of a pilot clinical trial.

甘氨酸和 N-乙酰半胱氨酸 (GlyNAC) 补充剂可改善老年人的谷胱甘肽缺乏、氧化应激、线粒体功能障碍、炎症、胰岛素抵抗、内皮功能障碍、基因毒性、肌肉力量和认知能力：一项初步临床试验的结果

期刊:Clinical and Translational Medicine
影响因子:6.8
doi:10.1002/ctm2.372
Kumar Premranjan, Liu Chun, Hsu Jean W, Chacko Shaji, Minard Charles, Jahoor Farook, Sekhar Rajagopal V
炎症/感染
氧化应激
炎症
线粒体
发表日期：2021
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Severe Glutathione Deficiency, Oxidative Stress and Oxidant Damage in Adults Hospitalized with COVID-19: Implications for GlyNAC (Glycine and N-Acetylcysteine) Supplementation

因 COVID-19 住院的成人患者严重谷胱甘肽缺乏、氧化应激和氧化损伤：补充 GlyNAC（甘氨酸和 N-乙酰半胱氨酸）的影响

期刊:Antioxidants
影响因子:
doi:10.3390/antiox11010050
Premranjan Kumar, Ob Osahon, David B Vides, Nicola Hanania, Charles G Minard, Rajagopal V Sekhar
表观遗传
新冠
发表日期：2021
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Supplementing Glycine and N-acetylcysteine (GlyNAC) in Aging HIV Patients Improves Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Endothelial Dysfunction, Insulin Resistance, Genotoxicity, Strength, and Cognition: Results of an Open-Label Clinical Trial

老年 HIV 患者补充甘氨酸和 N-乙酰半胱氨酸 (GlyNAC) 可改善氧化应激、线粒体功能障碍、炎症、内皮功能障碍、胰岛素抵抗、基因毒性、强度和认知能力：一项开放标签临床试验的结果

期刊:Biomedicines
影响因子:3.9
doi:10.3390/biomedicines8100390
Premranjan Kumar, Chun Liu, James W Suliburk, Charles G Minard, Raja Muthupillai, Shaji Chacko, Jean W Hsu, Farook Jahoor, Rajagopal V Sekhar
免疫
艾滋病
发表日期：2020
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Emerging Prevention and Treatment Strategies to Control COVID-19

控制新冠肺炎的新兴预防和治疗策略

期刊:Pathogens
影响因子:3.3
doi:10.3390/pathogens9060501
Singh, Vipul K; Mishra, Abhishek; Singh, Shubhra; Kumar, Premranjan; Singh, Manisha; Jagannath, Chinnaswamy; Khan, Arshad
肺炎
新冠
微生物学
发表日期：2020
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CHILDHOOD RISK AND PROTECTION FOR ADULT COGNITION

儿童时期风险与保护对成人认知的影响

期刊:BMC Psychiatry
影响因子:3.6
doi:10.1186/s12888-015-0666-8
Forstmeier, Simon; Maercker, Andreas; Lee, Gina; Kong, Jooyoung; Carr, Deborah; Engelman, Michal; Kumar, Premranjan; Sekhar, Rajagopal; Engelman, Michal; Lee, Gina; Whetung, Cliff; Gonzales, Ernest; Lin, Zhuoer; Chen, Xi; Greenfield, E; Moorman, S; Reynolds, C A
神经科学
发表日期：2018
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